CLINICAL RESEARCH
 
KEYWORDS
TOPICS
ABSTRACT
Introduction:
We analyzed trends in the tracheal, bronchial, and lung (TBL) cancer disease burdens attributable to respiratory system-related risk factors in 204 countries and territories from 1990 to 2019.

Material and methods:
Based on the results of the 2019 Global Burden of Disease study, we calculated and analyzed the estimated annual percentage changes (EAPCs) in the age-standardized disability-adjusted life year (DALY) rates and death rates of TBL cancer attributable to total and four individual risk factors globally, regionally, and nationally.

Results:
From 1990 to 2019, the age-standardized DALY rate and death rate of TBL cancer only attributable to ambient particulate matter pollution increased globally, and in all Socio-Demographic Index (SDI) quintiles, except for high SDI quintiles. Among regions, the most significant increases in those attributable to smoking were seen in East Asia, while those attributable to ambient particulate matter pollution and secondhand smoke were observed in Western Sub-Saharan Africa. Among countries, the most significant increases in those attributable to smoking were observed in São Tomé and Príncipe (EAPC = 1.76) and Bulgaria (EAPC = 1.90), those attributable to ambient particulate matter pollution were observed in Equatorial Guinea, those attributable to secondhand smoke were found in Lesotho (EAPC = 2.01) and Lebanon (EAPC = 2.13), and those attributable to household air pollution from solid fuels were seen in Mozambique.

Conclusions:
The burden attributable to ambient particulate matter pollution is increasing, especially in regions such as Western Sub-Saharan Africa and East Asia, and countries such as Equatorial Guinea and Bhutan.

 
REFERENCES (18)
1.
Sung H, Ferlay J, Siegel RL, et al. Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin 2021; 71: 209-49.
 
2.
Bray F, Ferlay J, Soerjomataram I, et al. Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin 2018; 68: 394-424.
 
3.
Safiri S, Sohrabi MR, Carson-Chahhoud K, et al. Burden of tracheal, bronchus, and lung cancer and its attributable risk factors in 204 countries and territories, 1990 to 2019. J Thorac Oncol 2021; 16: 945-59.
 
4.
Vos T, Lim SS, Abbafati C, et al. Global burden of 369 diseases and injuries in 204 countries and territories, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019. Lancet 2020; 396: 1204-22.
 
5.
Murray CJ, Aravkin AY, Zheng P, et al. Global burden of 87 risk factors in 204 countries and territories, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019. Lancet 2020; 396: 1223-49.
 
6.
Deng Y, Zhao P, Zhou L, et al. Epidemiological trends of tracheal, bronchus, and lung cancer at the global, regional, and national levels: a population-based study. J Hematol Oncol 2020; 13: 98.
 
7.
World Health Organization. (2015). Fact sheet about health benefits of smoking cessation. WHO Tobacco Free Initiative. https://www. who. int/tobacco/quitting/benefits/en.
 
8.
Carson KV, Usmani ZA, Robertson TA, et al. Smoking cessation interventions for lung cancer patients. Lung Cancer Manag 2013; 2: 61-74.
 
9.
Chen R, Yin P, Meng X, et al. Fine particulate air pollution and daily mortality. A nationwide analysis in 272 Chinese cities. Am J Respir Crit Care Med 2017; 196: 73-81.
 
10.
Yu Q, Gao B, Li G. et al. Attributing risk burden of PM2. 5-bound polycyclic aromatic hydrocarbons to major emission sources: case study in Guangzhou, south China. Atm Environm 2016; 142: 313-23.
 
11.
Yang F, Tan J, Zhao Q, et al. Characteristics of PM 2.5 speciation in representative megacities and across China. Atm Chem Phys 2011; 11: 5207-19.
 
12.
Landrigan PJ, Fuller R, Acosta NJR, et al. La Commission Lancet sur la pollution et santé. Lancet 2017; 391: 462-512.
 
13.
US Environmental Protection Agency: Office of Air and Radiation. The benefits and costs of the Clean Air Act from 1990 to 2020. April 2011. https://www.epa.gov/sites/prod... (accessed March 30, 2017).
 
14.
Greenberg H, Leeder SR, Raymond SU. And why so great a “no?”: The donor and academic communities’ failure to confront global chronic disease. Global Heart 2016; 11: 381-5.
 
15.
Nugent R. A chronology of global assistance funding for NCD. Global Heart 2016; 11: 371-4.
 
16.
Kim AS, Ko HJ, Kwon JH, et al. Exposure to secondhand smoke and risk of cancer in never smokers: a meta-analysis of epidemiologic studies. Int J Environ Res Public Health 2018; 15: 1981.
 
17.
Mills AL, White MM, Pierce JP, et al. Home smoking bans among US households with children and smokers: opportunities for intervention. Am J Prev Med 2011; 41: 559-65.
 
18.
Zahno M, Michaelowa K, Dasgupta P, et al. Health awareness and the transition towards clean cooking fuels: evidence from Rajasthan. PLoS One 2020; 15: e0231931.
 
eISSN:1896-9151
ISSN:1734-1922
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