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CLINICAL RESEARCH
A silent crisis: two decades of anaemia trends among women in the Eastern Mediterranean Region (2000–2019)
RESEARCH PAPER
APOE suppresses osteosarcoma by modulating ferroptosis through the mTOR/Stat3 signaling pathway
CLINICAL RESEARCH
Association of the triglyceride glucose index with computed tomography-based low muscle mass
CLINICAL RESEARCH
CircRNA_103809/miR-516a/FBXL18 contributes to stemness and gemcitabine resistance of bladder cancer cells
RESEARCH PAPER
Does Regular Physical Activity During Hemodialysis Affect the Levels of FoxO Proteins and Myostatin Concentration?
Agnieszka Turoń-Skrzypińska, Alicja Mińko, Aleksandra Rył, Katarzyna Mańkowska, Aneta Cymbaluk-Płoska, Kazimierz Ciechanowski, Iwona Rotter
RESEARCH PAPER
Exploring the association between gut microbiota and venous thromboembolism using a Mendelian randomization analysis
RESEARCH PAPER
STXBP1 inhibits glioma progression by modulating ferroptosis and epithelial-mesenchymal transition
RESEARCH PAPER
Exploring the Association Between Asthma and Frailty: A Cross-Sectional and A Bidirectional Mendelian Randomization study
Shufei Peng, Huanxian Liu, Xianfeng Ren, Lijuan Guo, Shuai Li, Xiaohai Xu, Meikui Wu, Yi Tian, Bing Mu, Ruihang Chai, Zhixing Guo, Xiaoyan Liu, Hui Zheng, Cheng Ni
RESEARCH PAPER
Genetically predicted 1,400 blood metabolites related to the risk of ovarian cancer: A Mendelian randomization study
CLINICAL RESEARCH
Development and verification of a novel disulfidptosis-related lncRNA prognostic model for predicting the immune environment and treatment of breast cancer
STATE OF THE ART PAPER
Clinical applications of deep learning in distinguishing Benign from Malignant Pulmonary Nodules in CT Scans
RESEARCH PAPER
HER2-Low Status in Breast Cancer: Clinicopathological Factors and Prognostic Value.
Joanna Huszno, Zofia Kołosza, Ewa Stobiecka, Dorota Ponikiewska, Bogna Szcześniak, Jakub Simek, Ewa Chmielik
RESEARCH PAPER
The Effect of Spiritual Coping Skills on Psychological Resilience and Health Beliefs of Mothers with Children with Special Needs
RESEARCH PAPER
Risk factors of postoperative intracranial infection in individuals suffering from hypertensive intracerebral hemorrhage
CLINICAL RESEARCH
Global health implications of urticaria burden (1990–2021): a comprehensive analysis of trends across nations and regions
RESEARCH PAPER
The Plasma Metabolite-Mediated Relationship between Inflammatory Cytokines and Acute Respiratory Distress Syndrome
RESEARCH PAPER
Unraveling the Impact of Neonatal Jaundice on Allergic Diseases: A Mendelian Randomization Study
RESEARCH PAPER
Lipoprotein Lipase Deficiency: heterozygotes match homozygotes in severity
Dominika Szczęśniak, Małgorzata Bednarska - Makaruk, Olga Drgas, Karolina Kowalczyk, Magdalena M Kacprzak, Paweł Aleksandrowicz, Lidia Kotuła, Magdalena Mroczek
RESEARCH PAPER
Exploring the mediating role of plasma lipidome in the pathway from gut microbiota to dementia: A Mendelian randomization study
Binghan Li, xu Sun, Xiao Luo, Yuting Kan, Weisen Wang, Tianren Wang, Cheng Wu, Yongbo Hu, Xiaoying Bi
STATE OF THE ART PAPER
The Importance of TNF-α Signaling – Potential Risk Factor in Neurodegenerative and Cardiovascular Diseases
CLINICAL RESEARCH
Enhanced neuroprotection against Alzheimer’s disease by combining Inula viscosa with curcumin: an in vitro study
Ares Alizade, Gülüzar Özbolat, Seydi Ahmet Şengül, Mustafa Cellat, İbrahim Ozan Tekeli, Halil Mahir Kaplan, Menderes Yusuf Terzi
CLINICAL RESEARCH
Investigating causal relationships between coffee consumption and gynecological diseases: a Mendelian randomization study
RESEARCH PAPER
Visual impairment and frailty: insight from genetic correlation and Mendelian randomization
RESEARCH PAPER
Research based on nucleotide polymorphism reveals the role of inflammatory cytokines in regulating the influence of blood metabolites on drug-related osteonecrosis.
Yazhou Li, Jiang Peng, Yanbin Wu, Junming Zhang, Xianghui Mei, Jiazhou Wu, Zexian Liu, Tao Qian, Junli Wang, Zaodi Mi, Ying He, Xiaohan Sun, Aiyuan Wang
CLINICAL RESEARCH
ACOT1 eQTL: a gene involved in lipid metabolism that modulates erectile dysfunction progression via metabolites
BASIC RESEARCH
Bidirectional causal association between type 1 diabetes and autoimmune diseases: a Mendelian randomization study
Liang Han, Youpeng Su, Hua Huang, Jiahui Yan, Tingting Li, Xin Ba, Weiji Lin, Ruiyuan Zhang, Pan Shen, Yao Huang, Ying Huang, Kai Qin, Yu Wang, Zhe Chen, Liang Zou, Shenghao Tu
EXPERIMENTAL RESEARCH
Correlative study on the expression of adipokine CTRP9 in a rat model of right ventricular outflow tract obstruction
CLINICAL RESEARCH
An immune escape-related gene signature for predicting the prognostic and immune microenvironment in osteosarcoma
CLINICAL RESEARCH
Risk stratification of soft tissue sarcoma based on activity of prognostic molecules associated with unpolarized macrophages
CLINICAL RESEARCH
RXRA induces endoplasmic reticulum stress via ATP2A3 transcriptional modulation in ovarian cancer cells
Lina Zhao, Lidong Zeng, Shan Tan, Qin Lu, Xiaofeng Wang, Jun Jiang, Yiming Wang, Jianqiao Peng, Qi Zhang
CLINICAL RESEARCH
Identifying the causal relationship between gut microbiota and lymphoma disease: a Mendelian randomization study and meta-analysis
CLINICAL RESEARCH
Establishing reference intervals for serum glutathione reductase in healthy adults
CLINICAL RESEARCH
Clinical effects of stent implantation on lower extremity deep venous thrombosis with severe iliac vein stenosis
CLINICAL RESEARCH
Sleep disorders and renal failure: exploring the role of creatinine and sleep apnea syndrome through cross-sectional studies and Mendelian randomization analysis
RESEARCH PAPER
Exploring necroptosis-associated genes: implications for immune responses and therapeutic strategies in diabetic foot ulcers
RESEARCH PAPER
Cuproptosis-induced up-regulation of RBM24 suppresses tumor metastasis via MAPK signaling blockage in colorectal cancer
Tianchen Huang, Dongxiao Bai, Yong Zhang, Kan Li, Zhipeng Guo, Lei Li, Xiaodong Han, Yachao Wu, Yanshan Xin, Weijie Wang
RESEARCH PAPER
Machine learning for the prediction of in-ICU mortality in sepsis: an observational study using the MIMIC IV database
Sitong Liu, Lingmin Gong, Weiwei Hu, Jiaxin Cai, Yuhui Yang, Shiyu Chen, Baibing Mi, Yaling Zhao, Leilei Pei, Fangyao Chen
CLINICAL RESEARCH
A persistent burden: global prevalence of and changes in anaemia by country income in children aged 6–59 months (2000–2019)
CLINICAL RESEARCH
The rare glucose response curve during oral glucose tolerance tests in pregnant Chinese women and its association with preterm birth
STATE OF THE ART PAPER
Proceeding and Treatment of Breast Cancer in Pregnant Women
Katarzyna Mielniczek, Magdalena Leśniewska, Katarzyna Chawrylak, Zuzanna Pelc, Katarzyna Sędłak, Wojciech P. Polkowski, Karol Rawicz-Pruszyński
CLINICAL RESEARCH
Trajectories of cardiovascular risk factors during childhood as predictors of subclinical atherosclerosis in young adults
RESEARCH LETTER
Association between the IGF family members and UTUC: a Mendelian randomization study
RESEARCH PAPER
Facts and myths about use and effect of statins in patients with dyslipidaemia - a survey of physicians.
CLINICAL RESEARCH
The protective effect of sodium-glucose cotransporter 2 inhibitors and the incidence of ovarian cancer: a nationwide cohort preliminary study
CLINICAL RESEARCH
Withaferin-A inhibits colorectal cancer growth and metastasis by targeting the HSP90/HIF-1α/EMT axis
Editor's Choice
RESEARCH PAPER
Telomere length across the spectrum of metabolic health – an analysis from the LIPIDOGEN2015 study
Maciej Banach, Martyna Fronczek, Anna Goc, Mateusz Lejawa, Ewa Boniewska-Bernacka, Tadeusz Osadnik, Anna Pańczyszyn, Joanna Katarzyna Strzelczyk, Natalia Pawlas, Marek Gierlotka, Marcin Goławski, Karol Krystek, Agnieszka Gach, Kamila Osadnik, Jacek Jóźwiak
RESEARCH PAPER
Mechanistic Study of Long Non-Coding RNA SNHG3 in Promoting Prostate Cancer Proliferation and Invasion
RESEARCH PAPER
Unveiling the Immune Related ceRNA Network in Osteoarthritis: Key Biomarkers and Therapeutic Targets
RESEARCH PAPER
Association between immune cells and membranous nephropathy: a two-sample Mendelian randomization study
Editor's Choice
RESEARCH PAPER
Sleep Disturbances and Heart Failure: Observational Study and Mendelian Randomization Study
STATE OF THE ART PAPER
Cellular therapy for traumatic brain injury in adults: a meta-analysis of controlled clinical trials
Mujahid Alizada, Jinxiang Wu, Mirwais Alizada, James Reeves Mbori Ngwayi, Muhebullah Alizada, Shu Lin, Hongzhi Gao
RESEARCH PAPER
Inflammation response index (SIRI) is associated with all-cause and cardiovascular mortality in maintenance hemodialysis patients
Editor's Choice
RESEARCH PAPER
The causal effects of placental weight on atherosclerotic cardiovascular disease: a Mendelian randomization and mediation analysis
CLINICAL RESEARCH
Effective treatment for fatty liver of liraglutide via inhibiting endoplasmic reticulum stress, oxidative stress and apoptosis pathways
RESEARCH PAPER
Therapeutic Potential of Mesenchymal Stem Cells in Cisplatin-Induced Acute Kidney Injury via ASK-1/TXNIP Pathway Modulation
CLINICAL RESEARCH
High levels of uric acid upregulate endothelin receptors: the role of MAPK pathways in an in vitro study
Editor's Choice
CLINICAL RESEARCH
Assessing the impact of a wheat flour and baker’s yeast restricted diet vs. calorie restriction in non-alcoholic fatty liver disease patients
Enver Ciftel, Aleksandra Klisic, Serpil Ciftel, Jelena Kotur Stevuljevic, Gokhan Tonkaz, Ramazan Dayanan, Arzu Bilen, Habib Bilen, Ilyas Capoglu, Filiz Mercantepe
Editor's Choice
BASIC RESEARCH
Application of Mendelian randomization to explore the genetic association between drinking habits of different beverages and sleep disorder
CLINICAL RESEARCH
Evaluation of differences between initial and recurrent acute pancreatitis in the intensive care unit
Editor's Choice
STATE OF THE ART PAPER
Implications for the role of natural products in Parkinson disease therapy
CLINICAL RESEARCH
Causal association between vitamin D levels and neonatal jaundice: results from a Mendelian randomization study
BASIC RESEARCH
Comparative investigation of immune-related biomarkers related to alopecia areata subtypes
CLINICAL RESEARCH
The association between metabolic associated fatty liver disease and depression in adults: the role of physical activity levels and types
Editor's Choice
RESEARCH PAPER
Resumption versus discontinuation of direct oral anticoagulation after an episode of gastrointestinal bleeding: a systematic review and meta-analysis of rebleeding episodes
Bianca Codrina Morarasu, Laurentiu Sorodoc, Stefan Morarasu, Emilia Adriana Marciuc, Raluca Ecaterina Haliga, Alexandr Ceasovschih, Mihai Constantin, Alexandra Stoica, Alexandra Diana Diaconu, Bogdan Ionut Dobrovat, Anca Haisan, Victorita Sorodoc
RESEARCH PAPER
sαKlotho protein is a useuful biomarker and a promising cardioprotective agent in acute heart failure
Joanna Płonka, Agnieszka Olejnik, Anna Klus, Ewa Gawrylak-Dryja, Natalia Wężyk, Lidia Rzepiela, Klaudia Dąbrowska, Iwona Bil-Lula, Marek Gierlotka
CLINICAL RESEARCH
Risk factors for cerebral hyperperfusion syndrome after carotid revascularization: a meta-analysis involving 158,624 participants
CLINICAL RESEARCH
Causal association of plasminogen activators and their inhibitors with Alzheimer’s disease: a Mendelian randomization study
EXPERIMENTAL RESEARCH
β-estradiol alleviates hypoxic-ischemic brain damage in neonatal rats through the GPER1-mediated AKT/NF-κB signaling pathway
Guangyun Zhang, Dawei Yuan, Tiegang Lv, Huafeng Li, Yanli Zhang, Yong Ding, Juan Cui, Min Li, Jing Yu, Jing Chen, Xiangping Xu
Editor's Choice
RESEARCH PAPER
A simplified cardiac amyloidosis score is associated with all-cause and cardiovascular disease mortality and morbidity, in the general population: the Ikaria Study.
Christina Chrysohoou, Demosthenes Panagiotakos, Dimitrios Tsiachris, Kyriakos Dimitriadis, George Lazaros, Kostas Tsioufis, Christodoulos Stefanadis
RESEARCH PAPER
Efficacy and safety of proton pump inhibitors for diabetes mellitus in patients with gastroesophageal reflux disease: A meta-analysis
CLINICAL RESEARCH
Uncovering the role of RPL8 in glutathione synthesis-dependent ferroptosis control in hepatocellular carcinoma
Editor's Choice
RESEARCH PAPER
Long-Term Trends in Intensive Care Unit Hospitalizations in Poland: Study Based on the National Hospital Registry, 2012-2021
Krzysztof Kanecki, Paweł Goryński, Michał Kowalczyk, Katarzyna Lewtak, Piotr Tyszko, Michał Rząd, Aneta Nitsch-Osuch
SYSTEMATIC REVIEW/META-ANALYSIS
The incidence of catheter-related bloodstream infections in different central venous access devices: a network meta-analysis of randomized controlled trials
Editor's Choice
RESEARCH PAPER
The Role of Vaccination, Testing, and Public Restriction Policies in COVID-19 Mortality and Incidence: Insights from Global Burden of Disease Regions
CLINICAL RESEARCH
Assessment of special hospital meals for diabetic patients. Discrepancies between provided meals, model menus and dietary guidelines: a hospital diet medical investigation (HDMI) study
Alicja M. Jodczyk, Alicja Kucharska, Mariusz Panczyk, Natalia Adamczyk, Karolina Turlej, Piotr Wierzbiński, Marcin Barylski, Adam R. Poliwczak, Maciej Janiszewski, Artur Mamcarz, Daniel Śliż
RESEARCH PAPER
A Retrospective Analysis of the Association of Obesity with Anthracycline and Trastuzumab-Induced Cardiotoxicity in the Treatment of Breast Cancer and Lymphoma
Mallorie L Huff, Ranju Gupta, Rahul Gupta, Kelly C Schadler, Shae Duka, Vienna Histon-Figliolini, Joshua Kalter, Amogh M Joshi, Nadeem V Ahmad, Wilbert S Aronow, Deborah W Sundlof
RESEARCH PAPER
Mesenchymal Stem Cells Suppress Kidney Injury molecule-1 Associated with Inhibition of Renal PKC/ NF-Kβ / STAT3 Fibrotic Signaling Pathway in Rats with Diabetic Nephropathy
Hasnaa A. Ebrahim, Asmaa Mohammed AlMohanna, Ayed A. Shati, Mohammed A. Alshehri, Thoraya Mohamed Elhassan A-Elgadir, Hailah M. Almohaimeed, Mohamed A. Haidara, Sara Adel Hosny, Amal Dawood, Asmaa M. ShamsEldeeen
CLINICAL RESEARCH
Wellbeing of parents raising children with autism spectrum disorder and the role of psychologists
RESEARCH PAPER
The C2HEST score on admission to hospital may successfully predict the clinical outcomes of COVID-19 in all-comers population
Adrian Doroszko, Małgorzata Trocha, Krzysztof Kujawa, Jędrzej Machowiak, Anna Jodkowska, Piotr Rola, Jarosław Sowizdraniuk, Paweł Lubieniecki, Mariusz Koral, Agata Stanek, Janusz Sokołowski, Ewa Anita Jankowska, Katarzyna Madziarska
Editor's Choice
CLINICAL RESEARCH
2024 update on postmarketing nutrivigilance safety profile: a line of dietary food supplements containing red yeast rice for dyslipidemia
Maciej Banach, Niki Katsiki, Gustavs Latkovskis, Dan Gaita, Carlos Escobar, Daniel Pella, Peter E. Penson, Federica Fogacci, Zeljko Reiner, Arrigo FG Cicero
RESEARCH PAPER
Investigating the Multi-Targeted Pharmacological profile of an Exopolysaccharide from Bacillus rugosus SYG20 via In Vitro Evaluation of its Antioxidant, Anti-inflammatory, Anti-diabetic, Wound Healing, and Antimicrobial Properties
Maha A. Alharbi, Aisha M.A Shahlol, Mona Othman I. Albureikan, Khalid Johani, Mohamed Gamal Elsehrawy, Mohammad El-Nablaway, Fayez M. Saleh, Ahmed Farouk Basyony, Shadi A. Zakai, Ahmed Ghareeb
EXPERIMENTAL RESEARCH
Effect of paeoniflorin on neuronal autophagy and Notch expression in tethered spinal cord in rats
CLINICAL RESEARCH
Correlation between SLC39A8 gene and body constitution-related phenotypes and hearing loss: a Mendelian randomization-based study
SYSTEMATIC REVIEW/META-ANALYSIS
Prevalence and incidence of chest wall deformities in children below 18 years old: the first systematic review and meta-analysis
RESEARCH PAPER
Antiviral flavonoids- and polyphenols-driven novel anti-HBV efficacy of Ilex paraguariensis
Sakina Niyazi, Mohammad K. Parvez, Tanzeel Ahmed, Omar A. Basudan, Md Tabish Rehman, Mohammed S. Al-Dosari, Rashed N. Herqash, Saleh I. Alqasoumi
EXPERIMENTAL RESEARCH
Excessive autophagy of myocardial cells promotes ferroptosis and exacerbates heart failure in the state of myocardial infarction
BASIC RESEARCH
Long noncoding RNA RP11-704M14.1 acts as a sponge of miR-6756-5p to promote neuronal proliferation by regulating ALOX15 expression
STATE OF THE ART PAPER
Recent advances in immune checkpoint inhibitor-based therapy of advanced hepatocellular carcinoma
CLINICAL RESEARCH
LncRNA KTN1-AS1 drives tumor progression in non-small cell lung cancer through the microRNA-153-3p/KLF5 axis
CLINICAL RESEARCH
YTHDF3-mediated m6A modification facilitates osteosarcoma progression through the FSP1-CoQ10-NAD(P)H axis to suppress ferroptosis
CLINICAL RESEARCH
The association between mixed exposure to per- and polyfluoroalkyl substances and the risk of diabetes
SYSTEMATIC REVIEW/META-ANALYSIS
Impact of low-level laser therapy on upper limb lymphoedema secondary to breast cancer: a systematic review and meta-analysis
Hisham Mohamed Hussein, Ahmed Maher Mohamed Gabr, Ibtisam Abdallah Fadulelmulla, Ahmed Abdelmageed Aldemery, Mohamed Marzouk Mohamed Ragab, Amany Raafat Mohamed, Ibrahim Metwally Dewir, Ahmed Abdelmoniem Ibrahim
CLINICAL RESEARCH
Symptom characteristics in self-observation and directional preference in patients with low back pain undergoing McKenzie therapy
CLINICAL RESEARCH
The effects of exposure to the Great Chinese Famine during the fetal stage and childhood on prevalence of hypertension in adulthood
CLINICAL RESEARCH
The relationship between ghrelin and iron metabolism in beta thalassaemia major patients
CLINICAL RESEARCH
Causal associations of circulating inflammatory proteins with sepsis: a two-sample Mendelian randomization study
CLINICAL RESEARCH
Which multimorbidity clusters are associated with longer hospital stays in hypertensive patients?
CLINICAL RESEARCH
Mitigating inflammatory response in breast cancer patients: the inhibitory effect of acupuncture and emotional nursing on the ST8SIA6-AS1/LINC00504/p38 pathway
CLINICAL RESEARCH
Cutaneous ulcers in anti-MDA5-positive dermatomyositis with rapidly progressive interstitial lung disease: a multicentre retrospective cohort study
Gang Wang, Ru Yang, Dong Yan, Lei Zhang, Lingxiao Xu, Fenghong Yuan, Ju Li, Min Wu, Zhanyun Da, Hua Wei, Lei Zhou, Songlou Yin, Jian Wu, Yan Lu, Dinglei Su, Lin Liu, Longxin Ma, Xiaoyan Xu, Huijie Liu, Tianli Ren, Yinshan Zang, Zhichun Liu
CLINICAL RESEARCH
A comprehensive analysis of immune characteristics and clinical prognosis in Asian COVID-19 patients infected with SARS-CoV-2 Omicron strain XBB sub-variants: a retrospective study of 450 cases
Fenge Li, Yupeng Wang, Mengli Jin, Hongli Li, Jin Yan, Jiandong Hu, Xianfeng Zhang, Chunwa Wu, Luqing Wei
CLINICAL RESEARCH
Prenatal ultrasound reassessment of the corpus callosum based on cortical connectivity information
CLINICAL RESEARCH
Exosomal hsa_circ_0035277 enhances the malignancy of gastric cancer by interacting with the m6A reader ELAVL1
CLINICAL RESEARCH
Age-related macular degeneration in the context of an update from the Global Burden of Disease Study 2019
CLINICAL RESEARCH
Red blood cell distribution width-to-albumin ratio: a prognostic biomarker of sepsis patients
CLINICAL RESEARCH
Early prediction of placenta accreta spectrum by evaluation of risk factors and ultrasound
Caihong Hu, Weishe Zhang, Chenlin Pei, Yuelan Liu, Yiran Fu, Qiaozhen Peng, Biaobiao Wang, Qi Li, Jingrui Huang
CLINICAL RESEARCH
SNHG15 is involved in the progression of atherosclerosis through targeted regulation of miR-370-3p and bioinformatics analysis
CLINICAL RESEARCH
Electrocardiographic repolarization parameters in children with arrhythmias and excessive body weight
Joanna Jaromin, Grażyna Markiewicz-Łoskot, Lesław Szydłowski, Agnieszka Kulawik, Agnieszka Chlebowczyk, Ewa Moric-Janiszewska
CLINICAL RESEARCH
A predictive nomogram for post-acute pancreatitis diabetes mellitus: a retrospective study
BASIC RESEARCH
METTL3-mediated miR-4534 maturation promotes IVDD progression by targeting the Sirt6-mediated Nrf2/HO-1 pathway
CLINICAL RESEARCH
The effect of post-thaw culture duration on singleton birthweight resulting from frozen embryo transfer cycles
CLINICAL RESEARCH
Novel biotargets of colorectal cancer peritoneal metastasis
Ye Gu, Qiang Liu, LeLe Li, Lingyun Li, Dongchao Xu, Liyun Zheng, Lu Xie, Sile Cheng, Hongzhang Shen, Yanbing Jie, Yifeng Zhou, Jianfeng Yang, Hangbin Jin, Xiaofeng Zhang
CLINICAL RESEARCH
LncRNA NEAT1 contributes to multiple myeloma progression via upregulating ARPC5 by sponging miR-133a
Fujue Wang, Piaorong Zeng, Zhongwei Lu, Xingxing Long, Cong Luo, Juan Zuo, Yixiong Cao, Feng Wen, Junjun Li, Zeyu Luo
SYSTEMATIC REVIEW/META-ANALYSIS
Association of stress, anxiety and depression with temporomandibular disorders in young adults – a systematic review
CLINICAL RESEARCH
Success in achieving LDL-C target values in a high-risk population in Slovakia: the SlovakLipid retrospective study
RESEARCH PAPER
Melatonin Enhances the Viability of Random-Pattern Skin Flaps by Activating the NRF2 pathway
CLINICAL RESEARCH
The effect of trehalose administration on the serum expression levels of microRNAs associated with lipid metabolism and the autophagy process in patients with myocardial infarction – post-hoc analysis of the IR-TREAT trial
Shiva Ganjali, Atena Mansouri, Željko Reiner, Tannaz Jamialahmadi, Seyed Adel Moallem, Sepideh Salehabadi, Maciej Banach, Amirhossein Sahebkar
CLINICAL RESEARCH
New-onset hypertension is not associated with systemic changes in inflammatory cytokine levels
Anna Dzieża-Grudnik, Olga Siga, Jolanta Walczewska, Barbara Wizner, Tomasz P Mikołajczyk, Joanna Sulicka-Grodzicka, Tomasz Grodzicki
CLINICAL RESEARCH
An improved random forest algorithm for tracing the origin of metastatic renal cancer tissues
RESEARCH PAPER
Risk factors of severe course and fatality in children hospitalized for COVID-19 – two centers cohort study.
CLINICAL RESEARCH
Predictive value of imaging manifestations of supratentorial hemorrhage in hematoma enlargement and clinical prognosis
SYSTEMATIC REVIEW/META-ANALYSIS
Efficacy and safety of tigecycline doses for ventilator-associated pneumonia caused by multiple resistant bacteria: a systematic review and meta-analysis
RESEARCH PAPER
The interaction of maternal obesity and administered betamethasone in the development of fetal respiratory distress syndrome
Mehmet Ak, Mefkure Eraslan Sahin, Erdem Sahin, Cevat Rıfat Cündübey, İlknur Çöl Madendağ, Yusuf Madendag, Osman Baştuğ
RESEARCH PAPER
The association between inefficient repair of oxidative DNA lesions and common polymorphisms of the key base excision repair genes as well as their expression levels in patients with Rheumatoid Arthritis
Grzegorz Galita, Joanna Sarnik, Gabriela Zajac, Olga Brzezinska, Tomasz Budlewski, Marta Poplawska, Karolina Przybyłowska-Sygut, Makowska Samanta Joanna, Tomasz Poplawski
CLINICAL RESEARCH
5E-led hospital-community-family care in patients with lung cancer surgery: it does work
RESEARCH PAPER
miR-10b-5p regulates venous endothelial cells in deep venous thrombosis by targeting MFG-E8
RESEARCH PAPER
Galectin-3 regulates skeletal muscle loss via TGFβ1-Smad2/3 signaling activation in mice
RESEARCH PAPER
Demarcated by bronchial or vascular landmarks? a study on the lower borders of the lower paratracheal lymph nodes
CLINICAL RESEARCH
Fat-free muscle index predicts overall survival in mass-forming intrahepatic cholangiocarcinoma patients: a sex-stratified analysis
Hualing Li, Han Zhang, Zhouyan Liao, Qiufeng Liu, Dong Kuang, Yan Luo, Xuemei Hu, Yang Yang, Zhen Li
RESEARCH PAPER
Acute poisonings among children and adolescents- results of the analysis of 401 cases
RESEARCH PAPER
Therapeutic effect of Lactobacillus reuteri DSM 17938 on feeding intolerance in preterm infants
RESEARCH PAPER
Hyperglycemic crisis and Parkinson disease: A retrospective cohort study based on nationwide data
Kun-Ming Chung, Chung-Han Ho, Yi-Chen Chen, Chien-Chin Hsu, Hung-Jung Lin, Jhi-Joung Wang, Kang-Ting Tsai, Chien-Cheng Huang
CLINICAL RESEARCH
Identification and validation of immune pathway subtyping in glioblastoma to predict clinical prognosis and immunotherapy response in patients
CLINICAL RESEARCH
The possibilities of prospective assessment of SARS-CoV-2 infection risk based on an artificial neural network model – a cross-sectional and in silico study
CLINICAL RESEARCH
The influence of gender on hip range of motion, hip muscle strength, gluteus medius thickness and M-mode ultrasound examination in asymptomatic university athletes: a cross-sectional study
Angel Gonzalez-de-la-Flor, Carlos Romero-Morales, Maria Garcia-Arrabe, Fabien Guerineau, Fermín Valera-Garrido, Francisco Minaya-Muñoz, Fernando García-Sanz, Jaime Almazan-Polo
STATE OF THE ART PAPER
Innovative technology for rapid molecular diagnostics: COVID-19 and other respiratory tract infections
Mariusz Gujski, Emilian Snarski, Katarzyna Dzierżanowska-Fangrat, Piotr Hoffman, Wojciech Braksator, Marcin Czech, Piotr Przygodzki, Jacek Walczak, Izabela Pieniążek, Maciej Grys, Jacek Mucha
BASIC RESEARCH
A novel seven-immune-gene-based model to improve prediction of prognosis of clear cell renal cell carcinoma
RESEARCH PAPER
Metformin attenuates the progression of esophageal squamous cell carcinoma by downregulating miR-141-3p to enhance SCEL
CLINICAL RESEARCH
Unique spectrum of driver gene mutations in patients with non-small cell lung carcinoma from coal-manufacturing districts in Southwest China
Jun-Ling Wang, Chun-Ju Yang, Juan Hu, Hong-Xia Liu, Meng-Xian Li, Zhe-Wei Fang, Jin-Si Yang, Rong Ma, Rui Dai, Qiang Xie, Rui Li, Jia-Ling Lv, Qiang-Bo Kan, Yan-Hong Gao, Ying-Yu Yang, Kun-Hua He, Ce Ci, Chao Zhang, Hong-Wei Li
STATE OF THE ART PAPER
Oligometastatic Disease in Prostate Cancer. Evolving paradigm: current knowledge, diagnostic techniques and treatment strategies
RESEARCH PAPER
Bioinformatics analysis and experiments identify CD74 as a potential immune target in ovarian carcinoma
RESEARCH PAPER
Cervical Mucus SLPI is a Predictive Biomarker for Timing of Delivery in Nulliparous Term Pregnancies with Unfavorable Cervix
Mefkure Eraslan Sahin, Erdem Sahin, Yusuf Madendag, Ilknur Col Madendag, Mehmet Mete Kirlangic, Cigdem Karakukcu
Editor's Choice
RESEARCH PAPER
Trehalose-induced alterations in serum expression levels of microRNAs associated with vascular inflammation in patients with coronary artery disease - the pilot results from the randomized controlled trial.
Shiva Ganjali, Tannaz Jamialahmadi, Mitra Abbasifard, Seyed Ahmad Emami, Zahra Tayarani-Najaran, Alexandra E. Butler, Maciej Banach, Amirhossein Sahebkar
RESEARCH PAPER
The potential protective effects of nintedanib against cardiac hypertrophy in vitro and in vivo
RESEARCH PAPER
Fresh autologous blood transfusion reverses erythrocytes damage by reducing oxidative stress via promoting mitochondrial metabolism and M2 macrophages polarization
Jia-Ming Xu, Lai-Wei You, Xiao-Fang Zhou, Yu Bai, Yong Cheng, Ying-Hui Cui, Xiao-Fei Chen, Jian-rong Guo
CLINICAL RESEARCH
Qualitative analysis of pain in cancer patients – psychological and clinical aspects
Marta Kulpa, Agata Ciuba, Mariola Kosowicz, Magdalena Flaga-Łuczkiewicz, Urszula Ziętalewicz, Beata Stypuła-Ciuba
SYSTEMATIC REVIEW/META-ANALYSIS
Oral immunotherapy prevents ventilator-associated pneumonia in premature infants: a meta-analysis and systematic review
SYSTEMATIC REVIEW/META-ANALYSIS
The associations between Enlarged Perivascular Spaces and partial Clinical symptoms: a meta-analysis
RESEARCH PAPER
Acupoint selection and acupuncture in treatment of premature ovarian failure by promoting secretion of exosome protein NELL2
CLINICAL RESEARCH
Does the duration of postmenopausal osteoporosis affect life quality and satisfaction?
SYSTEMATIC REVIEW/META-ANALYSIS
Association of the IL-4R Q576R polymorphism with asthma: a meta-analysis
RESEARCH PAPER
The etiologic role of Epstein-Barr virus and Cytomegalovirus infections in breast cancer development: a meta-analysis of case-control studies
Bahaeldin K. Elamin, Khalid Mohamed Adam, Ali Mahmoud Edris, Mohammed Abbas, Muhanad Alhujaily, Mutasim E. Ibrahim
CLINICAL RESEARCH
Pro-inflammatory and anti-inflammatory cytokines as candidate markers in the diagnosis and assessment of Crohn’s disease activity
Krystyna Słowińska-Solnica, Dorota Pawlica-Gosiewska, Katarzyna Gawlik, Danuta Owczarek, Dorota Cibor, Bogdan Solnica, Małgorzata Malczewska-Malec
RESEARCH PAPER
Outcomes of SARS-CoV-2 infection in patients under treatment with pharmacological immunosuppression. A Swiss cohort study.
Antonio Galante, Benedetta Terziroli Beretta-Piccoli, Alberto Pagnamenta, Lorenzo Ruinelli, Massimo Leo, Andrea De Gottardi
CLINICAL RESEARCH
A worsened prognosis for patients after stroke with newly diagnosed atrial fibrillation compared to having a preexisting arrhythmia
CLINICAL RESEARCH
Reticulocyte hemoglobin equivalent as a diagnostic parameter of iron deficiency anemia in infants age 1–4 months
RESEARCH PAPER
Coexistence of low testosterone and metabolic syndrome associated with increased arterial stiffness in male patients with type 2 diabetes
Shih-Ming Chuang, Kat-Yien Ngu, Chun-Chuan Lee, Ming-Nan Chien, Yueh-Chiu Huang, Hong-Mou Shih, Sung-Chen Liu
SYSTEMATIC REVIEW/META-ANALYSIS
The use of extracorporeal membrane oxygenation in COVID-19: a systematic review
Marius Andrei Zavalichi, Georgiana Ionescu, Cătălina Marina Arsenescu Georgescu, Adelina Mihaescu, Carmen Diana Cimpoesu, Gabriel Cimpoesu, Simona Daniela Zavalichi, Cristian Stătescu, Atalay Demiray, Mehmet Kanbay, Adrian Covic, Ionut Nistor
RESEARCH PAPER
The protective effects of Azilsartan against hypoxia in endometrial stromal cells: an implication in endometriosis
RESEARCH PAPER
Synergistic antitumor effects of 5-FU and Apatinib on papillary thyroid cancer in vitro and in vivo
Min Meng, Xin Ye, Xia Yang, Guanghui Huang, Zhigang Wei, Yang Ni, Wenhong Li, Xiaoying Han, Jiao Wang
BASIC RESEARCH
Effect and mechanism of immune surveillance activated by autotransfusion on reducing liver cancer metastasis based on HLA-DQB1/PDCD1
Laiwei You, Yu Bai, Ying-Hui Cui, Jin-Huo Wang, Na Yao, Xiao-Fang Zhou, Xiao-Fei Chen, Jian-Rong Guo
RESEARCH PAPER
ADPKD protects against diabetogenic effects associated with genetically-predicted lactase persistence.
Maria Pietrzak-Nowacka, Krzysztof Safranow, Agnieszka Boroń, Małgorzata Ryder-Woźniak, Kazimierz Ciechanowski, Ciechanowicz Andrzej
RESEARCH PAPER
The Relationship between Preoperative FDG PET/CT Uptake and Survival in Patients with Lung Cancer
SYSTEMATIC REVIEW/META-ANALYSIS
Correlation of RASSF1A gene methylation with gastric cancer and its clinical features: a meta-analysis
RESEARCH PAPER
Clinical outcomes of early-progressed follicular lymphoma in Korea: a multicenter, retrospective analysis
Jun Ho Yi, Seok Jin Kim, Dok Hyun Yoon, Cheolwon Suh, Won-Sik Lee, Deok Hwan Yang, Jae-Cheol Jo, Youngil Koh, Jeong-Ok Lee, Byeong Su Kim, Sung Nam Lim, Mi Hwa Heo, Byeong Seok Sohn, Yoon Seok Choi, Jinny Park, Hyo Jung Kim, Soon Il Lee, Sung Yong Oh, Won Seog Kim
RESEARCH PAPER
Intensive care unit readmissions following isolated coronary artery surgery
Marek Grochla, Piotr Knapik, Piotr Suwalski, Bartłomiej Perek, Marek Cisowski, Tomasz Hirnle, Krzysztof Filipiak, Michał Oskar Zembala
CLINICAL RESEARCH
CBX3 promotes ovarian cancer progression by regulating p53/p21-mediated glucose metabolism via inhibiting NCOR2
CLINICAL RESEARCH
Teenager dietary behavior and health literacy in China: influencing factors and coping strategies
STATE OF THE ART PAPER
Outcome-dependent twin growth curves for the bigger and smaller neonate within a Polish population – The best clinical support.
Anna Dera Szymanowska, Nikodem Horst, Wieslaw Markwitz, Mariola Ropacka-Lesiak, Krzysztof Szymanowski
RESEARCH PAPER
Combination of lymphocyte count and albumin concentration as a novel prognostic index in cholangiocarcinoma
Abdullah Ulku, Ahmet Gokhan Saritas, Ugur Topal, İsmail Cem Eray, Orcun Yalav, Cihan Atar, Atilgan Tolga Akcam
CLINICAL RESEARCH
Systemic sclerosis among hospitalized patients in Poland: a study based on a national hospital registry
Magdalena Bogdan, Aneta Nitsch-Osuch, Piotr Tyszko, Paweł Goryński, Agnieszka Barańska, Piotr Samel, Krzysztof Kanecki
SYSTEMATIC REVIEW/META-ANALYSIS
Duodenal versus gastric feeding in patients with traumatic brain injury: a systematic review and meta-analysis
CLINICAL RESEARCH
How often is right-power ablation equal to highpower ablation during pulmonary vein isolation under temperature control? Does the learning curve matter?
Edward Koźluk, Karolina Rogala, Dariusz Rodkiewicz, Agnieszka Piątkowska, Michał Walczewski, Grzegorz Opolski
