Retrospective evaluation of histopathological examinations in invasive ductal breast cancer of no special type: an analysis of 691 patients
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Submission date: 2015-04-24
Final revision date: 2015-06-22
Acceptance date: 2015-07-08
Online publication date: 2016-03-04
Publication date: 2017-10-30
Arch Med Sci 2017;13(6):1408–1415
Introduction: Invasive ductal carcinoma is the most common type of breast cancer in women and accounts for about 80% of all breast cancers. The aim of this study was to evaluate the relationship between the histological grade, tumor size and lymph node status in a group of 691 patients with invasive ductal breast cancer of no special type (IDC-NST).
Material and methods: The material consisted of histological preparations derived from 691 patients treated for IDC-NST.
Results: Regarding the histological grade of malignancy, the largest group of IDC-NST constituted grade 2 (53.96%) and grade 3 (28.98%) tumors. During the analysis of the pre-operative staging of studied cancers, it was found that the largest group among the IDC-NST tumors comprised those assessed as stages T1c (34.59%) and T2 (35.31%). It was noted that in all investigated IDC-NST, women without metastasis to regional lymph nodes constituted the largest group (pN0) (45.44%). In 60.64% of patients with ICD-NST, no distant organ metastases (M0) were identified, and in 39.36% of patients those could not be assessed (Mx).
Conclusions: Among IDC-NST cases, the most common are T1c and T2. The largest group of patients with IDC-NST consisted of those in whom the disease severity was as assessed as I and IIA. A relationship was found between IDC-NST of histological grades 1 and 2 and presence of metastasis to lymph nodes.