LETTER TO THE EDITOR
 
TOPICS
REFERENCES (21)
1.
Wu J, Deng X, Luo J, et al. Update in the treatment of cirrhotic patients with portal vein thrombosis. Clin Mol Hepatol 2025; 31: 1139-66.
 
2.
Volk ML, Ogola GO, Northup PG. Portal vein thrombosis in patients with cirrhosis. Proc (Bayl Univ Med Cent) 2025; 38: 121-5.
 
3.
Salembier A, Verhamme M, Verhamme P, Van Moerkercke W. Acute non-cirrhotic portal vein thrombosis: review. Acta Gastroenterol Belg 2018; 81: 318-22.
 
4.
Li Q, Piao Y, Zhang Y, Qi X. Case Report: First attempt by off-label use of tenecteplase to treat acute extensive portal venous system thrombosis. Front Cardiovasc Med 2024; 11: 1342529.
 
5.
Kollabathula A, Sharma S, Kumar N, et al. Plasminogen activator inhibitor-1 4G/5G promoter polymorphism in adults with splanchnic vein thrombosis: a case-control study. Indian J Hematol Blood Transfus 2022; 38: 169-72.
 
6.
Zhang Q, Jin Y, Li X, et al. Plasminogen activator inhibitor-1 (PAI-1) 4G/5G promoter polymorphisms and risk of venous thromboembolism – a meta-analysis and systematic review. Vasa 2020; 49: 141-6.
 
7.
Naushad S, Jamal NJ, Angalena R, Prasad CK, Devi AR. Hyperhomocysteinemia and the compound heterozygous state for methylene tetrahydrofolate reductase are independent risk factors for deep vein thrombosis among South Indians. Blood Coagul Fibrinolysis 2007; 18: 113-7.
 
8.
Liu F, Silva D, Malone MV, Seetharaman K. MTHFR A1298C and C677T polymorphisms are associated with increased risk of venous thromboembolism: a retrospective chart review study. Acta Haematol 2017; 138: 208-15.
 
9.
Ventura P, Venturelli G, Marcacci M, et al. Hyperhomocysteinemia and MTHFR C677T polymorphism in patients with portal vein thrombosis complicating liver cirrhosis. Thromb Res 2016; 141: 189-95.
 
10.
Gemmati D, Serino ML, Trivellato C, Fiorini S, Scapoli GL. C677T substitution in the methylenetetrahydrofolate reductase gene as a risk factor for venous thrombosis and arterial disease in selected patients. Haematologica 1999; 84: 824-8.
 
11.
Qi X, Yang Z, De Stefano V, Fan D. Methylenetetrahydrofolate reductase C677T gene mutation and hyperhomocysteinemia in Budd-Chiari syndrome and portal vein thrombosis: a systematic review and meta-analysis of observational studies. Hepatol Res 2014; 44: E480-98.
 
12.
Ames PR, D’Andrea G, Arcaro A, et al. Homozygous MTHFR C677T carriers develop idiopathic portal vein thrombosis 20 years earlier than wild type. Blood Coagul Fibrinolysis 2024; 35: 180-6.
 
13.
Gao M, Feng N, Zhang M, Ti X, Zuo X. Meta-analysis of the relationship between methylenetetrahydrofolate reductase C677T and A1298C polymorphism and venous thromboembolism in the Caucasian and Asian. Biosci Rep 2020; 40: BSR20200860.
 
14.
Jang MJ, Jeon YJ, Choi WI, et al. The 677C>T mutation of the MTHFR gene increases the risk of venous thromboembolism in Koreans and a meta-analysis from Asian population. Clin Appl Thromb Hemost 2013; 19: 309-14.
 
15.
Hosseini S, Kalantar E, Hosseini MS, Tabibian S, Shamsizadeh M, Dorgalaleh A. Genetic risk factors in patients with deep venous thrombosis, a retrospective case control study on Iranian population. Thromb J 2015; 13: 35.
 
16.
Wang B, Xu P, Shu Q, Yan S, Xu H. Combined effect of MTHFR C677T and PAI-1 4G/5G polymorphisms on the risk of venous thromboembolism in Chinese lung cancer patients. Clin Appl Thromb Hemostasis 2021; 27: 10760296211031291.
 
17.
Qi X, Han G, Fan D. The preferable treatment for cirrhotic portal vein thrombosis: anticoagulation or transjugular intrahepatic portosystemic shunt? Hepatology 2010; 51: 713-4.
 
18.
Xu X, Guo X, Wang R, et al. Low-molecular-weight heparin followed by rivaroxaban for acute occlusive portomesenteric vein thrombosis in a cirrhotic patient treated with multiple endoscopic variceal procedures. Ann Hepatol 2020; 19: 573-7.
 
19.
Senzolo M, Sartori TM, Rossetto V, et al. Prospective evaluation of anticoagulation and transjugular intrahepatic portosystemic shunt for the management of portal vein thrombosis in cirrhosis. Liver Int 2012; 32: 919-27.
 
20.
de Franchis R, Bosch J, Garcia-Tsao G, Reiberger T, Ripoll C. Baveno VII – renewing consensus in portal hypertension. J Hepatol 2022; 76: 959-74.
 
21.
Shenoy A, Davis JPE. Contemporary management of portal vein thromboses in patients with and without cirrhosis. Curr Opin Gastroenterol 2025; 41: 97-103.
 
eISSN:1896-9151
ISSN:1734-1922
Journals System - logo
Scroll to top