ONCOLOGY / RESEARCH LETTER
 
KEYWORDS
TOPICS
ABSTRACT
Introduction:
The direction of the causal link between solid cancers and elevated plasma vitamin B12 (B12) remains uncertain.

Material and methods:
We retrospectively included patients having two B12 measurements with a B12 initially ≥ 1000 ng/l and a solid cancer diagnosed between the measurements. Patients were included in the Curative or Supportive group according to their treatments.

Results:
B12 changes over time differed among groups (p = 0.001): +157.4 ng/L/month in the Supportive care group versus -171.6 ng/L/month in the Curative care group.

Conclusions:
The decrease of plasma B12 in cases of curative care could suggest that this B12 elevation is secondary to solid cancers.

eISSN:1896-9151
ISSN:1734-1922