There are a few reports documenting proton pump inhibitor-induced lupus erythematosus. Here, we present a 57-year-old woman treated with lansoprazole for chronic duodenitis, who subsequently developed extensive annular erythematous lesions on the skin. Laboratory examination revealed anti-Ro antibodies, leucopoenia and decreased C3 complement level. The skin histology demonstrated vacuolar degeneration of the epidermal basal layer and lymphocytic perivascular infiltrate in the dermis. Subacute cutaneous lupus erythematosus was diagnosed, possibly related to lansoprazole. The drug was discontinued and the patient received prednisone and ranitidine. Complete clearance of skin lesions was noted within 4 weeks and no relapse occurred upon corticosteroid discontinuation.
We process personal data collected when visiting the website. The function of obtaining information about users and their behavior is carried out by voluntarily entered information in forms and saving cookies in end devices. Data, including cookies, are used to provide services, improve the user experience and to analyze the traffic in accordance with the Privacy policy. Data are also collected and processed by Google Analytics tool (more).
You can change cookies settings in your browser. Restricted use of cookies in the browser configuration may affect some functionalities of the website.