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RESEARCH LETTER
Limited confidence in cervical cancer screening – unusually increased carcinoembryonic antigen expression resulting in the rapid development of cervical intraepithelial neoplasia grade 2
1
The Student Scientific Society (STN) of the Poznan University of Medical Sciences, Poznan, Poland
2
Erasmus Course Goethe-Universität, Frankfurt am Main, Germany
3
Department of Oncologic Surgery, Greater Poland Cancer Centre, Poznan, Poland
4
Department of Mother’s and Child’s Health, Poznan University of Medical Sciences, Poznan, Poland
Submission date: 2025-04-18
Final revision date: 2025-05-06
Acceptance date: 2025-05-08
Online publication date: 2025-06-17
Corresponding author
Alicja Rzymska
The Student Scientific Society (STN) of the Poznan University of Medical Sciences Poznan, Poland Erasmus Course Goethe-Universität Frankfurt am Main Germany
The Student Scientific Society (STN) of the Poznan University of Medical Sciences Poznan, Poland Erasmus Course Goethe-Universität Frankfurt am Main Germany
TOPICS
REFERENCES (10)
1.
Kainz C, Gitsch G, Kohlberger P, et al. Human papillomavirus infections and carcinoembryonic antigen expression in cervix intra-epithelial neoplasia of intermediate grade. Pathologe 1993; 14: 264-6.
2.
Luo R, Chen X, Zhu L. Cervical glandular intraepithelial neoplasia: a clinicopathologic and immunohistochemical analysis of 80 cases. Zhonghua Bing Li Xue Za Zhi 2013; 42: 32-6.
3.
Tendler A, Kaufman HL, Kadish AS. Increased carcinoembryonic antigen expression in cervical intraepithelial neoplasia grade 3 and in cervical squamous cell carcinoma. Hum Pathol 2000; 31: 1357-62.
4.
Farzaneh F, Shahghassempour S, Noshine B, et al. Application of tumor markers SCC-Ag, CEA, and TPA in patients with cervical precancerous lesions. Asian Pac J Cancer Prev 2014; 15: 3911-4.
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Jin Y, Kim SC, Kim HJ, et al. Use of autoantibodies against tumor-associated antigens as serum biomarkers for primary screening of cervical cancer. Oncotarget 2017; 8: 105425-39.
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Becker S, Jonigk D, Luft A, et al. COVID-19 can lead to rapid progression of cervical intraepithelial neoplasia by dysregulating the immune system: a hypothesis. J Reprod Immunol 2022; 154: 103763.
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Bedell SL, Goldstein LS, Goldstein AR, Goldstein AT. Cervical cancer screening: past, present, and future. Sex Med Rev 2020; 8: 28-37.
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Nedjai B, Reuter C, Ahmad A, et al. Molecular progression to cervical precancer, epigenetic switch or sequential model? Int J Cancer 2018; 143: 1720-30.
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Charoonwatana T, Boonlikit S, Yanaranop M. Progression of precancerous cervical lesion predicted by p16 protein immunohistochemistry in Rajavithi Hospital. Asian Pac J Cancer Prev 2019; 20: 1809-15.
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Wan KM, Oehler MK. Rapid progression of low-grade cervical dysplasia into invasive cancer during natalizumab treatment for relapsing remitting multiple sclerosis. Case Rep Oncol 2019; 12: 59-62.
| eISSN: | 1896-9151 |
| ISSN: | 1734-1922 |
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