PEDIATRICS / STATE OF THE ART PAPER
 
KEYWORDS
TOPICS
ABSTRACT
Nanotechnology has emerged as a critical technique for overcoming medicines’ primary (bio)pharmaceutical disadvantages and enabling active or passive targeting of certain cells and organs. Most paediatric treatments are based on adult clinical experience. However, there is a solid concept that medication pharmacokinetics and therapeutic outcomes differ in children and adults. The interaction of certain medicines with their target receptors varies with the maturity of various organs and systems. Usual observations are seen for adverse and toxic side effects, and so the implementation of innovative technologies (e.g. nanotechnology) in the paediatric population is very difficult in this environment. This article aims to deliver an overview of numerous initiatives to utilise nanotechnology to cure illnesses in children. We first discuss basic in vitro research through preclinical and clinical trials aimed at treating paediatric infectious illnesses and solid tumours using nanotechnology, despite little existing literature on this subject. Finally, future perspectives of nanomedicine for the paediatric population are elaborated.
eISSN:1896-9151
ISSN:1734-1922