Introduction:
We aimed to estimate the incidence of depression among women of childbearing age between 1990 and 2019 in terms of age, gender, country, and socio-economic development index (SDI).

Material and methods:
This study analyzed trends in age-standardized incidence rates (ASIR), and disability adjusted life years (DALY) using data from the Global Burden of Disease Study. We calculated the Estimated Annual Percentage Change (EAPC) and its corresponding 95% confidence interval (CI).

Results:
From 1990 to 2019, the ASIR (per 100000) and age-standardized DALY rate (per 100000) of depression in women of childbearing age showed a decreasing trend, with EAPC values of -0.53 and -0.44, respectively. However, Singapore's ASIR and Cuba's age-standardized DALY rate have the lowest EAPC (-2.24 and -2.11). Among the 21 geographical regions, the ASIR and DALY in Central Latin America have the highest EAPC (EAPC of 0.74 and 0.66, respectively), while East Asia has the lowest EAPC (-1.79 and -1.45, respectively). When looking at the changes in ASIR and age-standardized DALY rates from a national perspective, Mexico, Spain, and Germany have the highest increase in ASIR and age-standardized DALY rates. The EAPC of depression ASIR in pregnant woman is 1.55, 1.46, and 1.17, respectively, and the EAPC of depression age-standardized DALY rate in women of childbearing age is 1.40, 1.29, and 1.01, respectively.

Conclusions:
There was a consistent downward trend in the burden of depression in women of childbearing age globally. However, certain countries and regions like Central Latin America and Mexico experienced an upward trend in ASIR and age-standardized DALY rates.