GASTROENTEROLOGY / RESEARCH LETTER
The risk of essential fatty acid insufficiency in patients with inflammatory bowel diseases: fatty acid profile of phospholipids in serum and in colon biopsy specimen
| 1 | Department of Clinical Biochemistry, Institute of Pediatrics, Jagiellonian University Medical College, Krakow, Poland |
| 2 | Department of Food Chemistry and Nutrition, Jagiellonian University Medical College, Krakow, Poland |
CORRESPONDING AUTHOR
Jolanta Bugajska
Department of Clinical Biochemistry, Institute of Pediatrics, Jagiellonian University Medical College, Krakow, Poland, Phone: +48 12 6580681
Department of Clinical Biochemistry, Institute of Pediatrics, Jagiellonian University Medical College, Krakow, Poland, Phone: +48 12 6580681
Submission date: 2022-02-15
Final revision date: 2022-05-13
Acceptance date: 2022-05-13
Online publication date: 2022-06-03
Arch Med Sci 2022;18(4):1103–1107
KEYWORDS
TOPICS
ABSTRACT
Introduction:
The aim of the study was to address the fatty acid (FA) status and its relationship with disease activity in patients with inflammatory bowel disease (IBD).
Material and methods:
FA levels of phospholipids fraction in serum and colon-biopsy specimen were measured in 17 patients with IBD.
Results:
A negative correlation between the histological activity of inflammation of the disease and the ratio of polyunsaturated FAs/no polyunsaturated FAs was observed. Moreover, the level of that ratio was lower in patients with IBDs as compared to control.
Conclusions:
The FA profile in serum and in colon-biopsy specimen in patients with IBD is characteristic for essential fatty acid insufficiency.
The aim of the study was to address the fatty acid (FA) status and its relationship with disease activity in patients with inflammatory bowel disease (IBD).
Material and methods:
FA levels of phospholipids fraction in serum and colon-biopsy specimen were measured in 17 patients with IBD.
Results:
A negative correlation between the histological activity of inflammation of the disease and the ratio of polyunsaturated FAs/no polyunsaturated FAs was observed. Moreover, the level of that ratio was lower in patients with IBDs as compared to control.
Conclusions:
The FA profile in serum and in colon-biopsy specimen in patients with IBD is characteristic for essential fatty acid insufficiency.
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