GASTROENTEROLOGY / RESEARCH LETTER
 
KEYWORDS
TOPICS
ABSTRACT
Introduction:
The aim of the study was to address the fatty acid (FA) status and its relationship with disease activity in patients with inflammatory bowel disease (IBD).

Material and methods:
FA levels of phospholipids fraction in serum and colon-biopsy specimen were measured in 17 patients with IBD.

Results:
A negative correlation between the histological activity of inflammation of the disease and the ratio of polyunsaturated FAs/no polyunsaturated FAs was observed. Moreover, the level of that ratio was lower in patients with IBDs as compared to control.

Conclusions:
The FA profile in serum and in colon-biopsy specimen in patients with IBD is characteristic for essential fatty acid insufficiency.

eISSN:1896-9151
ISSN:1734-1922