OBSTETRICS AND GYNAECOLOGY / STATE OF THE ART PAPER
The role of vitamin D in perinatology. An up-to-date
review
1,
2,3,
4,
5,
2,
2,
2
| 1 | Second Department of Obstetrics and Gynecology, Center of Postgraduate Medical
Education, Warsaw, Poland |
| 2 | First Department of Obstetrics and Gynecology, Center of Postgraduate Medical
Education, Warsaw, Poland |
| 3 | European Observatory of Health Inequalities, State University of Applied Sciences,
Kalisz, Poland |
| 4 | Department of Obstetrics and Gynecological Nursing, Faculty of Health Sciences,
Medical University of Gdansk, Gdansk, Poland |
| 5 | Students’ Scientific Association at the First Department of Obstetrics and
Gynecology, Medical University of Warsaw, Warsaw, Poland |
Submission date: 2018-03-02
Final revision date: 2018-06-24
Acceptance date: 2018-07-05
Online publication date: 2019-01-30
Publication date: 2021-07-16
Arch Med Sci 2021;17(4):992–1005
KEYWORDS
TOPICS
ABSTRACT
The role of vitamin D in perinatology is a subject of major interest in current medicine. There is growing evidence about the role of maternal vitamin D levels in pregnancy outcomes. The aim of this review is to summarize the current literature about the role of vitamin D in perinatology. Evidence from this review suggests associations between low levels of maternal vitamin D and higher risk of certain obstetrical complications. Vitamin D has been found to be related to preeclampsia, gestational diabetes mellitus, low birth weight, and preterm birth. The current literature supports vitamin D supplementation in pregnant women, but more high-quality data are necessary. The problem that remains is how to achieve an optimal 25-hydroxyvitamin D level. To determine the real benefits of vitamin D supplementation in pregnancy, we need high-quality trials in larger groups.
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