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Topic Biology, Molecular
BASIC RESEARCH
PARP9 knockdown confers protection against chemoresistance and immune escape of breast cancer cells by blocking the PI3K/AKT pathway
Arch Med Sci 2024;20(4):1228-1248
BASIC RESEARCH
Circ-VPS13C enhances cisplatin resistance in ovarian cancer via modulating miR-106b-5p/YWHAZ axis
Arch Med Sci 2024;20(4):1249-1267
CLINICAL RESEARCH
The tubular damage markers: neutrophil gelatinase-associated lipocalin and kidney injury molecule-1 in newborns with exposure to maternal diabetes during pregnancy
Arch Med Sci 2024;20(3):762-768
BASIC RESEARCH
Enoxolone suppresses apoptosis in chondrocytes and progression of osteoarthritis via modulating the ERK1/2 signaling pathway
Arch Med Sci 2024;20(3):947-961
BASIC RESEARCH
Genomic profiling of thymoma using a targeted high-throughput approach
Jelena Peric, Natalija Samaradzic, Vesna Skodric Trifunovic, Natasa Tosic, Jelena Stojsic, Sonja Pavlovic, Dragana Jovanovic
Arch Med Sci 2024;20(3):909-917
BASIC RESEARCH
miR-149-5p mitigates tumor necrosis factor-α-induced chondrocyte apoptosis by inhibiting TRADD
Arch Med Sci 2024;20(2):602-611
CLINICAL RESEARCH
Immunohistochemical evaluation of osteopontin expression in triple-negative breast cancer
Magdalena Niedolistek, Marta M. Fudalej, Aleksandra Sobiborowicz, Anna Liszcz, Michał P. Budzik, Maciej Sobieraj, Janusz Patera, Aleksandra Czerw, Urszula Religioni, Maria Sobol, Andrzej Deptała, Anna M. Badowska-Kozakiewicz
Arch Med Sci 2024;20(2):436-443
EXPERIMENTAL RESEARCH
miR-29a activates expression of α-cardiac myosin heavy chain via β1 thyroid hormone receptor in neonatal rats
Arch Med Sci 2024;20(2):641-654
BASIC RESEARCH
TLR4 knockdown by miRNA-140-5p improves tendinopathy: an in vitro study
Arch Med Sci 2024;20(2):582-601
BASIC RESEARCH
lncRNA GAPLINC regulates vascular endothelial cell apoptosis in atherosclerosis
Arch Med Sci 2024;20(1):216-232
BASIC RESEARCH
Therapeutic properties of isoliquiritigenin with molecular modeling studies: investigation of anti-pancreatic acinar cell tumor and HMG-CoA reductase inhibitor activity for treatment of hypercholesterolemia
Arch Med Sci 2023;19(6):1842-1849
BASIC RESEARCH
Introducing a novel chemotherapeutic drug formulated with anthraflavic acid for treating human breast carcinoma and type 2 diabetes mellitus
Arch Med Sci 2023;19(6):1850-1858
RESEARCH LETTER
Expression of CXCL12-CXCR4/CXCR7 chemokines in splenic fibrosis of cirrhotic spleen and its therapeutic significance
Arch Med Sci 2023;19(5):1569-1575
STATE OF THE ART PAPER
Cardiac microRNAs: diagnostic and therapeutic potential
Anna Kabłak-Ziembicka, Rafał Badacz, Michał Okarski, Magdalena Wawak, Tadeusz Przewłocki, Jakub Podolec
Arch Med Sci 2023;19(5):1360-1381
EXPERIMENTAL RESEARCH
Alternate-day fat diet and exenatide modulate the brain leptin JAK2/STAT3/SOCS3 pathway in a fat diet-induced obesity and insulin resistance mouse model
Arch Med Sci 2023;19(5):1508-1519
BASIC RESEARCH
Variation in the gene encoding the co-inhibitory molecule BTLA is associated with survival in patients treated for clear cell renal carcinoma – results of a prospective cohort study
Krzysztof Tupikowski, Anna Partyka, Edyta A. Pawlak, Kuba Ptaszkowski, Romuald Zdrojowy, Irena Frydecka, Agnieszka Hałoń, Lidia Karabon
Arch Med Sci 2023;19(5):1454-1462
STATE OF THE ART PAPER
Nanoparticles: a breakthrough in COVID-19 prevention, diagnosis and treatment
Aleksandra Skwarek, Aleksandra Gąsecka, Miłosz J. Jaguszewski, Łukasz Szarpak, Tomasz Dzieciątkowski, Krzysztof J. Filipiak
Arch Med Sci 2023;19(5):1410-1420
BASIC RESEARCH
Equisetum arvense L aqueous extract: a novel chemotherapeutic supplement for treatment of human colon carcinoma
Arch Med Sci 2023;19(5):1472-1478
STATE OF THE ART PAPER
Bioactive lipid-based therapeutic approach to COVID-19 and other similar infections
Arch Med Sci 2023;19(5):1327-1359
BASIC RESEARCH
Flow cytometric characterization of cell surface markers to differentiate between fibroblasts and mesenchymal stem cells of different origin
Arch Med Sci 2023;19(5):1487-1496
CLINICAL RESEARCH
The diagnostic value of circulating miR-532-5p in patients with asymptomatic carotid artery stenosis and its predictive significance for the occurrence of cerebral ischaemic events
Arch Med Sci 2023;19(5):1236-1242
CLINICAL RESEARCH
The influence of adalimumab treatment on the systemic gene expression in patients with psoriatic arthritis – preliminary report
Agata Krawczyk, Barbara Strzałka-Mrozik, Dominika Wcisło-Dziadecka, Magdalena Kimsa-Dudek, Celina Kruszniewska-Rajsa, Joanna Gola
Arch Med Sci 2023;19(4):1080-1091
EXPERIMENTAL RESEARCH
Protective effect of hydrogen sulfide is mediated by negative regulation of epigenetic histone acetylation in Parkinson’s disease
Arch Med Sci 2023;19(4):1124-1135
RESEARCH LETTER
The RYR3 gene is involved in Wharton’s jelly derived mesenchymal stem cell treatment of Alzheimer’s disease in rats
Arch Med Sci 2023;19(3):820-824
CLINICAL RESEARCH
Association of BAFF and BAFF-R polymorphisms with sarcoidosis in a Greek patient cohort
Maria Martinou, Hector Katifelis, Elias Gialafos, Kiril Todorov Atliev, Spiridon Papiris, Maria Gazouli
Arch Med Sci 2023;19(3):672-677
STATE OF THE ART PAPER
Heterogeneity in biomarkers, mitogenome and genetic disorders of the Arab population with special emphasis on large-scale whole-exome sequencing
Arch Med Sci 2023;19(3):765-783
CLINICAL RESEARCH
mRNA expression profiling of mitochondrial subunits in subjects with Parkinson’s disease
Michele Salemi, Filomena Cosentino, Giuseppe Lanza, Mariagiovanna Cantone, Maria Grazia Salluzzo, Giorgio Giurato, Eugenia Borgione, Giovanna Marchese, Sandro Santa Paola, Bartolo Lanuzza, Corrado Romano, Raffaele Ferri
Arch Med Sci 2023;19(3):678-686
CLINICAL RESEARCH
Association of PRDM16 rs12409277 and CtBP2 rs1561589 gene polymorphisms with lipid profile of adolescents
Nela Maksimovic, Vanja Vidovic, Tatjana Damnjanovic, Biljana Jekic, Nada Majkic Singh, Slavko Simeunovic, Dara Savic Bozovic, Stojko Vidovic, Ivana Novakovic
Arch Med Sci 2023;19(3):593-599
BASIC RESEARCH
miR-200a-3p predicts prognosis and inhibits bladder cancer cell proliferation by targeting STAT4
Arch Med Sci 2023;19(3):724-735
CLINICAL RESEARCH
Subtype of breast cancer influences sentinel lymph node positivity
Arch Med Sci 2023;19(3):618-625
BASIC RESEARCH
miRNA-19a exerts an anti-apoptotic effect in spinal cord injured rats via the PTEN pathway
Arch Med Sci 2023;19(3):744-756
RESEARCH LETTER
The emerging role of ferroptosis in myocardial fibrosis of atrial fibrillation
Arch Med Sci 2023;19(2):507-512
Editor's Choice
STATE OF THE ART PAPER
Menopause and women’s cardiovascular health: is it really an obvious relationship?
Arch Med Sci 2023;19(2):458-466
BASIC RESEARCH
Induction of apoptosis in RL95-2 human endometrial cancer cells by combination treatment with docosahexaenoic acid and triacsin C
Arch Med Sci 2023;19(2):488-498
CLINICAL RESEARCH
Prognostic value of XIAP and survivin expression in locally advanced breast cancer patients treated with anthracycline-based neoadjuvant chemotherapy
Piotr Pluta, Dorota Jesionek-Kupnicka, Agnieszka Pluta, Kamil Brzozowski, Marcin Braun, Joanna Kubicka-Wołkowska, Janusz Piekarski
Arch Med Sci 2023;19(2):343-354
BASIC RESEARCH
Long non-coding RNA LINC00336 as an independent prognostic indicator and an oncogenic lncRNA in bladder cancer
Arch Med Sci 2023;19(2):478-487
BASIC RESEARCH
Expression differences between proteins responsible for DNA damage repair according to the Gleason grade as a new heterogeneity marker in prostate cancer
Damian Jaworski, Arkadiusz Gzil, Paulina Antosik, Izabela Zarębska, Joanna Dominiak, Izabela Neska-Długosz, Anna Kasperska, Dariusz Grzanka, Łukasz Szylberg
Arch Med Sci 2023;19(2):499-506
RESEARCH LETTER
Extended application of BACs-on-Beads technique in prenatal diagnosis
Arch Med Sci 2023;19(1):250-257
BASIC RESEARCH
MiR-1286 inhibits lung cancer growth through aerobic glycolysis by targeting PKM2
Arch Med Sci 2023;19(1):151-159
BASIC RESEARCH
Increased IL-1α expression is correlated with bladder cancer malignant progression
Arch Med Sci 2023;19(1):160-170
BASIC RESEARCH
Hsa_circ_0017728 as an oncogene in gastric cancer by sponging miR-149 and modulating the IL-6/STAT3 pathway
Arch Med Sci 2022;18(6):1558-1571
BASIC RESEARCH
The identification and preliminary study of lncRNA TUG1 and its related genes in hepatocellular carcinoma
Arch Med Sci 2022;18(6):1582-1595
EXPERIMENTAL RESEARCH
MALAT1/miR-320a in bone marrow mesenchymal stem cells function may shed light on mechanisms underlying osteoporosis
Arch Med Sci 2022;18(6):1638-1649
CLINICAL RESEARCH
MiR-146a and miR-155 polymorphisms in Egyptian patients with Behcet’s disease
Olfat G. Shaker, Omayma O. Abdelaleem, Nermeen A. Fouad, Naglaa A. Ahmed, Hoda A. Hussein, Enas G. Ibrahem, Abdelrahmaan A. Mohamed, Othman M. Ahmed, Doaa Y. Ali
Arch Med Sci 2022;18(6):1467-1474
RESEARCH LETTER
A variant in microRNA-124 is involved in the control of neural cell apoptosis and associated with recovery after spinal cord injury (SCI)
Arch Med Sci 2022;18(5):1399-1403
BASIC RESEARCH
The toxicology properties of modified hydrothermal nanotitania extraction
Ahmad Mukifza Harun, Nor Farid Mohd Noor, Ramizu Shaari, Lio Xing Ying, Mohamad Ezany Yusoff, Mohammad Khursheed Alam
Arch Med Sci 2022;18(5):1338-1341
BASIC RESEARCH
Stem cell-like circulating tumor cells indicate poor prognosis in gastric cancer
Arch Med Sci 2022;18(5):1297-1307
BASIC RESEARCH
The effects of rivaroxaban, an oral anticoagulant, on human IVD primary cultures
Arch Med Sci 2022;18(4):1062-1070
BASIC RESEARCH
Encapsulation of granulocyte colony-stimulating factor and granulocyte-macrophage colony-stimulating factor in liposomes prepared by thin film hydration and their transfer to mesenchymal stem cells and cord blood hematopoietic stem cells
Sławomir Lewicki, Monika Leśniak, Agnieszka Sobolewska-Ruta, Aneta Lewicka, Marta Grodzik, Eugeniusz K. Machaj, Marek Saracyn, Jacek Z. Kubiak, Zygmunt Pojda
Arch Med Sci 2022;18(4):1051-1061
EXPERIMENTAL RESEARCH
Increased oxytocinergic system activity in the cardiac muscle in spontaneously hypertensive SHR rats
Agnieszka Wsol, Agata Gondek, Martyna Podobinska, Marek Chmielewski, Elżbieta Sajdel-Sułkowska, Agnieszka Cudnoch-Jędrzejewska
Arch Med Sci 2022;18(4):1088-1094
CLINICAL RESEARCH
Angiopoietin-2 as a biomarker of non-ST-segment elevation myocardial infarction in patients with or without type 2 diabetes
Tomasz Skowerski, Katarzyna Nabrdalik, Hanna Kwiendacz, Maciej Pajak, Katarzyna Mizia-Stec, Zbigniew Gasior, Janusz Gumprecht
Arch Med Sci 2022;18(3):624-631
BASIC RESEARCH
MiR-29b-3p affects growth and biological functions of human extravillous trophoblast cells by regulating bradykinin B2 receptor
Arch Med Sci 2022;18(2):499-522
CLINICAL RESEARCH
Association between myostatin serum concentration and body fat level in peri- and postmenopausal women
Iwona Bojar, Radosław Mlak, Iwona Homa-Mlak, Monika Prendecka, Alfred Owoc, Teresa Małecka-Massalska
Arch Med Sci 2022;18(2):365-375
RESEARCH LETTER
Endothelin-1 gene and endothelin receptor A gene polymorphisms in severe pulmonary hypertension associated with rheumatic mitral valve disease
Arch Med Sci 2022;18(1):260-266
BASIC RESEARCH
Plumbagin triggers redox-mediated autophagy through the LC3B protein in human papillomavirus-positive cervical cancer cells
Vaiyapuri Subbarayan Periasamy, Jegan Athinarayanan, Girija Ramankutty, Mohammad A. Akbarsha, Ali A. Alshatwi
Arch Med Sci 2022;18(1):171-182
BASIC RESEARCH
Rs1894720 polymorphism is associated with the risk of age-related cataract by regulating the proliferation of epithelial cells in the lens via the signalling pathway of MIAT/miR-26b/BCL2L2
Arch Med Sci 2022;18(1):223-236
CLINICAL RESEARCH
TERT rs2853669 as a predictor for overall survival in patients with acute myeloid leukaemia
Florin Tripon, Claudia Bănescu, Adrian P. Trifa, Andrei G. Crauciuc, Valeriu G. Moldovan, Alina Boglis, Istvan Benedek, Smaranda Demian, Carmen Duicu, Mihaela Iancu
Arch Med Sci 2022;18(1):103-111
BASIC RESEARCH
Long noncoding RNA SNHG20 promotes prostate cancer progression via upregulating DDX17
Arch Med Sci 2021;17(6):1752-1765
BASIC RESEARCH
Positive association and future perspectives of mitochondrial DNA copy number and telomere length – a pilot twin study
Dóra Melicher, Anett Illés, Levente Littvay, Ádám Domonkos Tárnoki, Dávid László Tárnoki, András Bikov, László Kunos, Dóra Csabán, Edit Irén Buzás, Mária Judit Molnár, András Falus
Arch Med Sci 2021;17(5):1191-1999
BASIC RESEARCH
Downregulation of long non-coding RNA B-Raf proto-oncogene-activated non-coding RNA reverses cisplatin resistance in laryngeal squamous cell carcinoma
Arch Med Sci 2021;17(5):1164-1174
STATE OF THE ART PAPER
Genetic syndromes with vascular malformations – update on molecular background and diagnostics
Adam Ustaszewski, Joanna Janowska-Głowacka, Katarzyna Wołyńska, Anna Pietrzak, Magdalena Badura-Stronka
Arch Med Sci 2021;17(4):965-991
BASIC RESEARCH
Long intergenic non-coding RNA, regulator of reprogramming (LINC-ROR) over-expression predicts poor prognosis in renal cell carcinoma
Arch Med Sci 2021;17(4):1016-1027
STATE OF THE ART PAPER
The role of vitamin D in perinatology. An up-to-date review
Michał Ciebiera, Cezary Wojtyła, Krzysztof Łukaszuk, Magdalena Zgliczyńska, Kornelia Zaręba, Wojciech Rawski, Grzegorz Jakiel
Arch Med Sci 2021;17(4):992-1005
BASIC RESEARCH