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Topic Biology, Molecular
CLINICAL RESEARCH
Decreased expression of cytokeratin 15 and tropoelastin in men with androgenetic alopecia and its relationship with increased expression of p15/p16
Miguel A. Ortega, María J. Álvarez-Rocha, Ángel Asúnsolo, Beatriz Romero, Santiago Coca, Melchor Álvarez-Mon, Julia Buján, Natalio García-Honduvilla
Arch Med Sci 2025;21(2):494-504
BASIC RESEARCH
MicroRNA let-7f protects against H2O2-induced oxidative damage in neuroblastoma cells by targeting AKT-2
Arch Med Sci 2025;21(2):648-657
EXPERIMENTAL RESEARCH
Fucoxanthin protects neonatal rat cardiomyocytes and attenuates high glucose-mediated oxidative stress via the AMPK pathway
Arch Med Sci 2025;21(1):272-284
EXPERIMENTAL RESEARCH
Adipose tissue-derived mesenchymal stem cells have better restorative capacity than bone marrow-derived cells in a cerebellar ataxic rat model
Arch Med Sci 2025;21(1):298-312
EXPERIMENTAL RESEARCH
Inhibition of inflammatory cell infiltration by antagonistic peptides that specifically bind to CCR5 via regulation of the NF-kB signaling pathway in rats with colitis
Arch Med Sci 2024;20(6):2022-2033
CLINICAL RESEARCH
Synergistic therapeutic approach for hemorrhoids: integrating mesenchymal stem cells with diosmin-hesperidin to target tissue edema and inflammation
Arch Med Sci 2024;20(5):1556-1566
BASIC RESEARCH
Oxymatrine inhibits the development of radioresistance in NSCLC cells by reversing EMT through the DcR3/AKT/GSK-3β pathway
Arch Med Sci 2024;20(5):1631-1654
Editor's Choice
CLINICAL RESEARCH
Association of vitamin D receptor gene polymorphisms with rheumatoid arthritis
Noelia Marquez Pete, Cristina Perez Ramirez, Maria del Mar Maldonado Montoro, Fernando Martinez Martinez, Fernando Fernández-Llimos, Antonio Sánchez Pozo, María del Carmen Ramirez Tortosa, Alberto Jiménez Morales
Arch Med Sci 2024;20(5):1529-1537
BASIC RESEARCH
PARP9 knockdown confers protection against chemoresistance and immune escape of breast cancer cells by blocking the PI3K/AKT pathway
Arch Med Sci 2024;20(4):1228-1248
BASIC RESEARCH
Circ-VPS13C enhances cisplatin resistance in ovarian cancer via modulating miR-106b-5p/YWHAZ axis
Arch Med Sci 2024;20(4):1249-1267
CLINICAL RESEARCH
The tubular damage markers: neutrophil gelatinase-associated lipocalin and kidney injury molecule-1 in newborns with exposure to maternal diabetes during pregnancy
Arch Med Sci 2024;20(3):762-768
BASIC RESEARCH
Enoxolone suppresses apoptosis in chondrocytes and progression of osteoarthritis via modulating the ERK1/2 signaling pathway
Arch Med Sci 2024;20(3):947-961
BASIC RESEARCH
Genomic profiling of thymoma using a targeted high-throughput approach
Jelena Peric, Natalija Samaradzic, Vesna Skodric Trifunovic, Natasa Tosic, Jelena Stojsic, Sonja Pavlovic, Dragana Jovanovic
Arch Med Sci 2024;20(3):909-917
BASIC RESEARCH
miR-149-5p mitigates tumor necrosis factor-α-induced chondrocyte apoptosis by inhibiting TRADD
Arch Med Sci 2024;20(2):602-611
CLINICAL RESEARCH
Immunohistochemical evaluation of osteopontin expression in triple-negative breast cancer
Magdalena Niedolistek, Marta M. Fudalej, Aleksandra Sobiborowicz, Anna Liszcz, Michał P. Budzik, Maciej Sobieraj, Janusz Patera, Aleksandra Czerw, Urszula Religioni, Maria Sobol, Andrzej Deptała, Anna M. Badowska-Kozakiewicz
Arch Med Sci 2024;20(2):436-443
EXPERIMENTAL RESEARCH
miR-29a activates expression of α-cardiac myosin heavy chain via β1 thyroid hormone receptor in neonatal rats
Arch Med Sci 2024;20(2):641-654
BASIC RESEARCH
TLR4 knockdown by miRNA-140-5p improves tendinopathy: an in vitro study
Arch Med Sci 2024;20(2):582-601
BASIC RESEARCH
lncRNA GAPLINC regulates vascular endothelial cell apoptosis in atherosclerosis
Arch Med Sci 2024;20(1):216-232
BASIC RESEARCH
Therapeutic properties of isoliquiritigenin with molecular modeling studies: investigation of anti-pancreatic acinar cell tumor and HMG-CoA reductase inhibitor activity for treatment of hypercholesterolemia
Arch Med Sci 2023;19(6):1842-1849
BASIC RESEARCH
Introducing a novel chemotherapeutic drug formulated with anthraflavic acid for treating human breast carcinoma and type 2 diabetes mellitus
Arch Med Sci 2023;19(6):1850-1858
RESEARCH LETTER
Expression of CXCL12-CXCR4/CXCR7 chemokines in splenic fibrosis of cirrhotic spleen and its therapeutic significance
Arch Med Sci 2023;19(5):1569-1575
STATE OF THE ART PAPER
Cardiac microRNAs: diagnostic and therapeutic potential
Anna Kabłak-Ziembicka, Rafał Badacz, Michał Okarski, Magdalena Wawak, Tadeusz Przewłocki, Jakub Podolec
Arch Med Sci 2023;19(5):1360-1381
EXPERIMENTAL RESEARCH
Alternate-day fat diet and exenatide modulate the brain leptin JAK2/STAT3/SOCS3 pathway in a fat diet-induced obesity and insulin resistance mouse model
Arch Med Sci 2023;19(5):1508-1519
BASIC RESEARCH
Variation in the gene encoding the co-inhibitory molecule BTLA is associated with survival in patients treated for clear cell renal carcinoma – results of a prospective cohort study
Krzysztof Tupikowski, Anna Partyka, Edyta A. Pawlak, Kuba Ptaszkowski, Romuald Zdrojowy, Irena Frydecka, Agnieszka Hałoń, Lidia Karabon
Arch Med Sci 2023;19(5):1454-1462
STATE OF THE ART PAPER
Nanoparticles: a breakthrough in COVID-19 prevention, diagnosis and treatment
Aleksandra Skwarek, Aleksandra Gąsecka, Miłosz J. Jaguszewski, Łukasz Szarpak, Tomasz Dzieciątkowski, Krzysztof J. Filipiak
Arch Med Sci 2023;19(5):1410-1420
BASIC RESEARCH
Equisetum arvense L aqueous extract: a novel chemotherapeutic supplement for treatment of human colon carcinoma
Arch Med Sci 2023;19(5):1472-1478
STATE OF THE ART PAPER
Bioactive lipid-based therapeutic approach to COVID-19 and other similar infections
Arch Med Sci 2023;19(5):1327-1359
BASIC RESEARCH
Flow cytometric characterization of cell surface markers to differentiate between fibroblasts and mesenchymal stem cells of different origin
Arch Med Sci 2023;19(5):1487-1496
CLINICAL RESEARCH
The diagnostic value of circulating miR-532-5p in patients with asymptomatic carotid artery stenosis and its predictive significance for the occurrence of cerebral ischaemic events
Arch Med Sci 2023;19(5):1236-1242
CLINICAL RESEARCH
The influence of adalimumab treatment on the systemic gene expression in patients with psoriatic arthritis – preliminary report
Agata Krawczyk, Barbara Strzałka-Mrozik, Dominika Wcisło-Dziadecka, Magdalena Kimsa-Dudek, Celina Kruszniewska-Rajsa, Joanna Gola
Arch Med Sci 2023;19(4):1080-1091
EXPERIMENTAL RESEARCH
Protective effect of hydrogen sulfide is mediated by negative regulation of epigenetic histone acetylation in Parkinson’s disease
Arch Med Sci 2023;19(4):1124-1135
RESEARCH LETTER
The RYR3 gene is involved in Wharton’s jelly derived mesenchymal stem cell treatment of Alzheimer’s disease in rats
Arch Med Sci 2023;19(3):820-824
CLINICAL RESEARCH
Association of BAFF and BAFF-R polymorphisms with sarcoidosis in a Greek patient cohort
Maria Martinou, Hector Katifelis, Elias Gialafos, Kiril Todorov Atliev, Spiridon Papiris, Maria Gazouli
Arch Med Sci 2023;19(3):672-677
STATE OF THE ART PAPER
Heterogeneity in biomarkers, mitogenome and genetic disorders of the Arab population with special emphasis on large-scale whole-exome sequencing
Arch Med Sci 2023;19(3):765-783
CLINICAL RESEARCH
mRNA expression profiling of mitochondrial subunits in subjects with Parkinson’s disease
Michele Salemi, Filomena Cosentino, Giuseppe Lanza, Mariagiovanna Cantone, Maria Grazia Salluzzo, Giorgio Giurato, Eugenia Borgione, Giovanna Marchese, Sandro Santa Paola, Bartolo Lanuzza, Corrado Romano, Raffaele Ferri
Arch Med Sci 2023;19(3):678-686
CLINICAL RESEARCH
Association of PRDM16 rs12409277 and CtBP2 rs1561589 gene polymorphisms with lipid profile of adolescents
Nela Maksimovic, Vanja Vidovic, Tatjana Damnjanovic, Biljana Jekic, Nada Majkic Singh, Slavko Simeunovic, Dara Savic Bozovic, Stojko Vidovic, Ivana Novakovic
Arch Med Sci 2023;19(3):593-599
BASIC RESEARCH
miR-200a-3p predicts prognosis and inhibits bladder cancer cell proliferation by targeting STAT4
Arch Med Sci 2023;19(3):724-735
CLINICAL RESEARCH
Subtype of breast cancer influences sentinel lymph node positivity
Arch Med Sci 2023;19(3):618-625
BASIC RESEARCH
miRNA-19a exerts an anti-apoptotic effect in spinal cord injured rats via the PTEN pathway
Arch Med Sci 2023;19(3):744-756
RESEARCH LETTER
The emerging role of ferroptosis in myocardial fibrosis of atrial fibrillation
Arch Med Sci 2023;19(2):507-512
Editor's Choice
STATE OF THE ART PAPER
Menopause and women’s cardiovascular health: is it really an obvious relationship?
Arch Med Sci 2023;19(2):458-466
BASIC RESEARCH
Induction of apoptosis in RL95-2 human endometrial cancer cells by combination treatment with docosahexaenoic acid and triacsin C
Arch Med Sci 2023;19(2):488-498
CLINICAL RESEARCH
Prognostic value of XIAP and survivin expression in locally advanced breast cancer patients treated with anthracycline-based neoadjuvant chemotherapy
Piotr Pluta, Dorota Jesionek-Kupnicka, Agnieszka Pluta, Kamil Brzozowski, Marcin Braun, Joanna Kubicka-Wołkowska, Janusz Piekarski
Arch Med Sci 2023;19(2):343-354
BASIC RESEARCH
Long non-coding RNA LINC00336 as an independent prognostic indicator and an oncogenic lncRNA in bladder cancer
Arch Med Sci 2023;19(2):478-487
BASIC RESEARCH
Expression differences between proteins responsible for DNA damage repair according to the Gleason grade as a new heterogeneity marker in prostate cancer
Damian Jaworski, Arkadiusz Gzil, Paulina Antosik, Izabela Zarębska, Joanna Dominiak, Izabela Neska-Długosz, Anna Kasperska, Dariusz Grzanka, Łukasz Szylberg
Arch Med Sci 2023;19(2):499-506
RESEARCH LETTER
Extended application of BACs-on-Beads technique in prenatal diagnosis
Arch Med Sci 2023;19(1):250-257
BASIC RESEARCH
MiR-1286 inhibits lung cancer growth through aerobic glycolysis by targeting PKM2
Arch Med Sci 2023;19(1):151-159
BASIC RESEARCH
Increased IL-1α expression is correlated with bladder cancer malignant progression
Arch Med Sci 2023;19(1):160-170
BASIC RESEARCH
Hsa_circ_0017728 as an oncogene in gastric cancer by sponging miR-149 and modulating the IL-6/STAT3 pathway
Arch Med Sci 2022;18(6):1558-1571
BASIC RESEARCH
The identification and preliminary study of lncRNA TUG1 and its related genes in hepatocellular carcinoma
Arch Med Sci 2022;18(6):1582-1595
EXPERIMENTAL RESEARCH
MALAT1/miR-320a in bone marrow mesenchymal stem cells function may shed light on mechanisms underlying osteoporosis
Arch Med Sci 2022;18(6):1638-1649
CLINICAL RESEARCH
MiR-146a and miR-155 polymorphisms in Egyptian patients with Behcet’s disease
Olfat G. Shaker, Omayma O. Abdelaleem, Nermeen A. Fouad, Naglaa A. Ahmed, Hoda A. Hussein, Enas G. Ibrahem, Abdelrahmaan A. Mohamed, Othman M. Ahmed, Doaa Y. Ali
Arch Med Sci 2022;18(6):1467-1474
RESEARCH LETTER
A variant in microRNA-124 is involved in the control of neural cell apoptosis and associated with recovery after spinal cord injury (SCI)
Arch Med Sci 2022;18(5):1399-1403
BASIC RESEARCH
The toxicology properties of modified hydrothermal nanotitania extraction
Ahmad Mukifza Harun, Nor Farid Mohd Noor, Ramizu Shaari, Lio Xing Ying, Mohamad Ezany Yusoff, Mohammad Khursheed Alam
Arch Med Sci 2022;18(5):1338-1341
BASIC RESEARCH
Stem cell-like circulating tumor cells indicate poor prognosis in gastric cancer
Arch Med Sci 2022;18(5):1297-1307
BASIC RESEARCH
The effects of rivaroxaban, an oral anticoagulant, on human IVD primary cultures
Arch Med Sci 2022;18(4):1062-1070
BASIC RESEARCH
Encapsulation of granulocyte colony-stimulating factor and granulocyte-macrophage colony-stimulating factor in liposomes prepared by thin film hydration and their transfer to mesenchymal stem cells and cord blood hematopoietic stem cells
Sławomir Lewicki, Monika Leśniak, Agnieszka Sobolewska-Ruta, Aneta Lewicka, Marta Grodzik, Eugeniusz K. Machaj, Marek Saracyn, Jacek Z. Kubiak, Zygmunt Pojda
Arch Med Sci 2022;18(4):1051-1061
EXPERIMENTAL RESEARCH
Increased oxytocinergic system activity in the cardiac muscle in spontaneously hypertensive SHR rats
Agnieszka Wsol, Agata Gondek, Martyna Podobinska, Marek Chmielewski, Elżbieta Sajdel-Sułkowska, Agnieszka Cudnoch-Jędrzejewska
Arch Med Sci 2022;18(4):1088-1094
CLINICAL RESEARCH
Angiopoietin-2 as a biomarker of non-ST-segment elevation myocardial infarction in patients with or without type 2 diabetes
Tomasz Skowerski, Katarzyna Nabrdalik, Hanna Kwiendacz, Maciej Pajak, Katarzyna Mizia-Stec, Zbigniew Gasior, Janusz Gumprecht
Arch Med Sci 2022;18(3):624-631
BASIC RESEARCH
MiR-29b-3p affects growth and biological functions of human extravillous trophoblast cells by regulating bradykinin B2 receptor
Arch Med Sci 2022;18(2):499-522
CLINICAL RESEARCH
Association between myostatin serum concentration and body fat level in peri- and postmenopausal women
Iwona Bojar, Radosław Mlak, Iwona Homa-Mlak, Monika Prendecka, Alfred Owoc, Teresa Małecka-Massalska
Arch Med Sci 2022;18(2):365-375
RESEARCH LETTER
Endothelin-1 gene and endothelin receptor A gene polymorphisms in severe pulmonary hypertension associated with rheumatic mitral valve disease
Arch Med Sci 2022;18(1):260-266
BASIC RESEARCH
Plumbagin triggers redox-mediated autophagy through the LC3B protein in human papillomavirus-positive cervical cancer cells
Vaiyapuri Subbarayan Periasamy, Jegan Athinarayanan, Girija Ramankutty, Mohammad A. Akbarsha, Ali A. Alshatwi
Arch Med Sci 2022;18(1):171-182
BASIC RESEARCH
Rs1894720 polymorphism is associated with the risk of age-related cataract by regulating the proliferation of epithelial cells in the lens via the signalling pathway of MIAT/miR-26b/BCL2L2
Arch Med Sci 2022;18(1):223-236
CLINICAL RESEARCH
TERT rs2853669 as a predictor for overall survival in patients with acute myeloid leukaemia
Florin Tripon, Claudia Bănescu, Adrian P. Trifa, Andrei G. Crauciuc, Valeriu G. Moldovan, Alina Boglis, Istvan Benedek, Smaranda Demian, Carmen Duicu, Mihaela Iancu
Arch Med Sci 2022;18(1):103-111
BASIC RESEARCH
Long noncoding RNA SNHG20 promotes prostate cancer progression via upregulating DDX17
Arch Med Sci 2021;17(6):1752-1765
BASIC RESEARCH
Positive association and future perspectives of mitochondrial DNA copy number and telomere length – a pilot twin study
Dóra Melicher, Anett Illés, Levente Littvay, Ádám Domonkos Tárnoki, Dávid László Tárnoki, András Bikov, László Kunos, Dóra Csabán, Edit Irén Buzás, Mária Judit Molnár, András Falus
Arch Med Sci 2021;17(5):1191-1999
BASIC RESEARCH
Downregulation of long non-coding RNA B-Raf proto-oncogene-activated non-coding RNA reverses cisplatin resistance in laryngeal squamous cell carcinoma
Arch Med Sci 2021;17(5):1164-1174
STATE OF THE ART PAPER
Genetic syndromes with vascular malformations – update on molecular background and diagnostics
Adam Ustaszewski, Joanna Janowska-Głowacka, Katarzyna Wołyńska, Anna Pietrzak, Magdalena Badura-Stronka
Arch Med Sci 2021;17(4):965-991
BASIC RESEARCH
Long intergenic non-coding RNA, regulator of reprogramming (LINC-ROR) over-expression predicts poor prognosis in renal cell carcinoma
Arch Med Sci 2021;17(4):1016-1027
STATE OF THE ART PAPER
The role of vitamin D in perinatology. An up-to-date review
Michał Ciebiera, Cezary Wojtyła, Krzysztof Łukaszuk, Magdalena Zgliczyńska, Kornelia Zaręba, Wojciech Rawski, Grzegorz Jakiel
Arch Med Sci 2021;17(4):992-1005
BASIC RESEARCH
Haemoglobin switching modulator SNPs rs5006884 is associated with increased HbA2 in β-thalassaemia carriers
Cyril Cyrus, Chittibabu Vatte, Shahanas Chathoth, Abdul Azeez Sayed, J. Francis Borgio, Mohammed Abdullah Alrubaish, Rawan Alfalah, Jana Alsaikhan, Amein K. Al Ali
Arch Med Sci 2021;17(4):1064-1074
RESEARCH LETTER
Serological testing for SARS-CoV-2 in Bosnia and Herzegovina: first report
Adna Ašić, Jasminka Prguda-Mujić, Lana Salihefendić, Larisa Bešić, Daria Ler, Ivana Čeko, Almira Hadžović-Džuvo, Sead Jažić, Rijad Konjhodžić, Damir Marjanović
Arch Med Sci 2021;17(3):823-826
BASIC RESEARCH
Modulation of Ki67 and myogenic regulatory factor expression by tocotrienol-rich fraction ameliorates myogenic program of senescent human myoblasts
Chun Min Tan, Nadwa Aqeela Mohd Najib, Nur Farahin Suhaimi, Nur Alia Halid, Vi Vien Cho, Saiful Idham Abdullah, Muhammad Zulhilmi Ismail, Shy Cian Khor, Faizul Jaafar, Suzana Makpol
Arch Med Sci 2021;17(3):752-763
EXPERIMENTAL RESEARCH
Salidroside regulates imbalance of Th17/Treg and promotes ischemic tolerance by targeting STAT-3 in cerebral ischemia-reperfusion injury
Arch Med Sci 2021;17(2):523-534
CLINICAL RESEARCH
Adipokine signatures of subcutaneous and visceral abdominal fat in normal-weight and obese women with different metabolic profiles
Arch Med Sci 2021;17(2):323-336
BASIC RESEARCH
MicroRNA-16 inhibits the lipopolysaccharide-induced inflammatory response in nucleus pulposus cells of the intervertebral disc by targeting TAB3
Arch Med Sci 2021;17(2):500-513
EXPERIMENTAL RESEARCH
Up-regulation of autophagy and apoptosis of cochlear hair cells in mouse models for deafness
Arch Med Sci 2021;17(2):535-641
LETTER TO THE EDITOR
Mesenchymal soluble factors confer imatinib drug resistance in chronic myelogenous leukemia cells
Arch Med Sci 2021;17(1):266-274
BASIC RESEARCH
CNTN-1 promotes docetaxel resistance and epithelial-to-mesenchymal transition via the PI3K/Akt signaling pathway in prostate cancer
Arch Med Sci 2021;17(1):152-165
EXPERIMENTAL RESEARCH
Effects of free and nanoparticulate curcumin on chemically induced liver carcinoma in an animal model
Eman Shawky Mohammed, Nadia M. El-Beih, Enas Ali El-Hussieny, Eman El-Ahwany, Marwa Hassan, Mona Zoheiry
Arch Med Sci 2021;17(1):218-227
BASIC RESEARCH
Resveratrol is cytotoxic and acts synergistically with NF-κB inhibition in osteosarcoma MG-63 cells
Arch Med Sci 2021;17(1):166-176
SYSTEMATIC REVIEW/META-ANALYSIS
IFN-γ +874 A>T (rs2430561) gene polymorphism and risk of pulmonary tuberculosis: a meta-analysis
Mohammed Y. Areeshi, Raju K. Mandal, Sajad A. Dar, Arshad Jawed, Mohd Wahid, Mohtashim Lohani, Aditya K. Panda, B. N. Mishra, Naseem Akhter, Shafiul Haque
Arch Med Sci 2021;17(1):177-188
BASIC RESEARCH
Inhibition of miR-22 promotes differentiation of osteoblasts and improves bone formation via the YWHAZ pathway in experimental mice
Arch Med Sci 2020;16(6):1419-1431
BASIC RESEARCH
MSK1 promotes cell proliferation and metastasis in uveal melanoma by phosphorylating CREB
Arch Med Sci 2020;16(5):1176-1188
BASIC RESEARCH
LncRNA PCAT-1 upregulates RAP1A through modulating miR-324-5p and promotes survival in lung cancer
Arch Med Sci 2020;16(5):1196-1206
LETTER TO THE EDITOR
Inverse correlation between levels of glycated haemoglobin and expression levels of SERCA protein in Mexican patients with type 2 diabetes mellitus
Octavio Galindo-Hernandez, Jesus Rene Machado-Contreras, Rodrigo Martinez-Corella, Tatiana Romero-Garcia, J. Gustavo Vazquez-Jimenez
Arch Med Sci 2020;16(5):1226-1228
CLINICAL RESEARCH
Klotho and vitamin D in multiple sclerosis: an Italian study
Concetta Scazzone, Luisa Agnello, Bruna Lo Sasso, Paolo Ragonese, Giulia Bivona, Sabrina Realmuto, Giorgia Iacolino, Caterina Maria Gambino, Chiara Bellia, Giuseppe Salemi, Marcello Ciaccio
Arch Med Sci 2020;16(4):842-847
BASIC RESEARCH
miR-133a-3p promotes apoptosis and induces cell cycle arrest by targeting CREB1 in retinoblastoma
Arch Med Sci 2020;16(4):941-956
LETTER TO THE EDITOR
Arachidonic and eicosapentaenoic acids induce oxidative stress to suppress proliferation of human glioma cells
Arch Med Sci 2020;16(4):974-983
CLINICAL RESEARCH
Association between oxidative stress biomarkers and concentrations of some metal ions in the blood of patients with brain tumors and hydrocephalus
Ljiljana Vujotić, Siniša Matić, Slavica Borković-Mitić, Aleksandar Stojsavljević, Jelena Mutić, Vladimir Baščarević, Miloš Joković, Slađan Pavlović
Arch Med Sci 2020;16(4):811-819
STATE OF THE ART PAPER
Ankyrins in human health and disease – an update of recent experimental findings
Arch Med Sci 2020;16(4):715-726
RESEARCH PAPER
State-of-the-art tools unveil potent drug targets amongst clinically approved drugs to inhibit helicase in SARS-CoV-2
J. Francis Borgio, Hind Saleh Alsuwat, Waad Mohammed Al Otaibi, Abdallah M. Ibrahim, Noor B Almandil, Lubna Ibrahim Al Asoom, Mohammed Salahuddin, Balu Kamaraj, Sayed AbdulAzeez
Arch Med Sci 2020;16(3):508-518
LETTER TO THE EDITOR
Spectrum of ALDH1 mRNA in smokers and non-smokers with adenocarcinoma or squamous cell lung carcinoma
Arch Med Sci 2020;16(3):709-713
BASIC RESEARCH
Long non-coding RNA SNHG1 promotes cell proliferation and invasion of hepatocellular carcinoma by acting as a molecular sponge to modulate miR-195
Arch Med Sci 2020;16(2):386-394
BASIC RESEARCH
Lysyl hydroxylase 3 increases collagen deposition and promotes pulmonary fibrosis by activating TGFβ1/Smad3 and Wnt/β-catenin pathways
Songjun Shao, Haiyan Fang, Lindi Duan, Xianwei Ye, Shanshan Rao, Jin Han, Yumei Li, Guohang Yuan, Weijia Liu, Xiangyan Zhang
Arch Med Sci 2020;16(2):436-445
BASIC RESEARCH
Establishment of stable cell lines in which the HBV genome replicates episomally for evaluation of antivirals
Arch Med Sci 2020;16(2):407-413
BASIC RESEARCH
Anticancer activity of sugiol against ovarian cancer cell line SKOV3 involves mitochondrial apoptosis, cell cycle arrest and blocking of the RAF/MEK/ERK signalling pathway
Arch Med Sci 2020;16(2):428-435
BASIC RESEARCH
Differential effect of adenosine on rhabdomyosarcoma migration and proliferation
Arch Med Sci 2020;16(2):414-427
EXPERIMENTAL RESEARCH
Effect of N-acetylcysteine on intimal hyperplasia and endothelial proliferation in rabbit carotid artery anastomosis
Arch Med Sci 2019;15(6):1576-1581
CLINICAL RESEARCH
MicroRNA-122a as a non-invasive biomarker for HCV genotype 4-related hepatocellular carcinoma in Egyptian patients
Eman G. E. El-Ahwany, Lobna Mourad, Mona M. K. Zoheiry, Hoda Abu-Taleb, Marwa Hassan, Raafat Atta, Moataz Hassanien, Suher Zada
Arch Med Sci 2019;15(6):1454-1461
EXPERIMENTAL RESEARCH
The role of interleukin-6 in intracellular signal transduction after chronic β-adrenergic stimulation in mouse myocardium
Magdalena Dziemidowicz, Tomasz A. Bonda, Siergiej Litvinovich, Andrzej Taranta, Maria M. Winnicka, Karol A. Kamiński
Arch Med Sci 2019;15(6):1565-1575
BASIC RESEARCH
Effects of vascular endothelial growth factor and epidermal growth factor on biological properties of gastric cancer cells
Arch Med Sci 2019;15(6):1498-1509
BASIC RESEARCH
Genes and metabolic pathway of sarcoidosis: identification of key players and risk modifiers
Mihailo I. Stjepanovic, Violeta Mihailovic-Vucinic, Vesna Spasovski, Jelena Milin-Lazovic, Vesna Skodric-Trifunovic, Sanja Stankovic, Marina Andjelkovic, Jovana Komazec, Ana Momcilovic, Milena Santric-Milicevic, Sonja Pavlovic
Arch Med Sci 2019;15(5):1138-1146
BASIC RESEARCH
STAT3 promotes chronic lymphocytic leukemia progression through upregulating SMYD3 expression
Arch Med Sci 2019;15(5):1163-1175
BASIC RESEARCH
Up-regulation of FTO gene expression was associated with increase in skeletal muscle mass in overweight male adolescents
Saeid Doaei, Naser Kalantari, Nastaran Keshavarz Mohammadi, Pantea Izadi, Maryam Gholamalizadeh, Hassan Eini-Zinab, Tuire Salonurmi, Alireza Mosavi Jarrahi, Shahram Rafieifar, Reza Janipoor, Mahnaz Sadeghypor, Ghasem Azizi Tabesh, Mark O. Goodarzi
Arch Med Sci 2019;15(5):1133-1137
CLINICAL RESEARCH
Expression of miRNAs-122, -192 and -499 in end stage renal disease associated with acute myocardial infarction
Lobna Abdelsalam, Alshaymaa A. Ibrahim, Aliaa Shalaby, Noha Osman, Assem Hashad, Dina Badawy, Hany Elghobary, Eman Amer
Arch Med Sci 2019;15(5):1247-1253
LETTER TO THE EDITOR
Association of polymorphisms of the TNFRSF11B and TNFSF11 genes with bone mineral density in postmenopausal women from western Mexico
Anahi González-Mercado, Josefina Y. Sánchez-López, Francisco J. Perea-Díaz, Maria T. Magaña-Torres, Mario Salazar-Páramo, Laura González-López, Mirna Gisel González-Mercado, Bertha Ibarra-Cortés
Arch Med Sci 2019;15(5):1352-1356
CLINICAL RESEARCH
Integrated analysis of lncRNA, miRNA and mRNA expression profiling in patients with systemic lupus erythematosus
Qin Zhang, Yan Liang, Hui Yuan, Si Li, Jie-Bing Wang, Xiao-Mei Li, Jin-Hui Tao, Hai-Feng Pan, Dong-Qing Ye
Arch Med Sci 2019;15(4):872-879
STATE OF THE ART PAPER
Hearing regeneration and regenerative medicine: present and future approaches
Arch Med Sci 2019;15(4):957-967
BASIC RESEARCH
MiR-509-5p improves the proliferative and invasive abilities of papillary thyroid carcinoma cells by inhibiting SFRP1
Arch Med Sci 2019;15(4):968-978
BASIC RESEARCH
Methylwogonin exerts anticancer effects in A375 human malignant melanoma cells through apoptosis induction, DNA damage, cell invasion inhibition and downregulation of the mTOR/PI3K/Akt signalling pathway
Arch Med Sci 2019;15(4):1056-1064
BASIC RESEARCH
Oridonin inhibits metastasis of human ovarian cancer cells by suppressing the mTOR pathway
Arch Med Sci 2019;15(4):1017-1027
EXPERIMENTAL RESEARCH
The anterior cingulate cortex projection to the dorsomedial striatum modulates hyperalgesia in a chronic constriction injury mouse model
Xiuxiu Zhuang, Luping Huang, Yixiao Gu, Lu Wang, Rong Zhang, Minyuan Zhang, Fei Li, Yiyi Shi, Yunchang Mo, Qinxue Dai, Chaoyi Wei, Junlu Wang
Arch Med Sci 2021;17(5):1388-1399
STATE OF THE ART PAPER
Mesothelin-targeted CAR-T cells for adoptive cell therapy of solid tumors
Arch Med Sci 2021;17(5):1213-1220
BASIC RESEARCH
Differential expression study of circular RNAs in exosomes from serum and urine in patients with idiopathic membranous nephropathy
Arch Med Sci 2019;15(3):738-753
BASIC RESEARCH
Glucose fluctuation increased mesangial cell apoptosis related to AKT signal pathway
Changjiang Ying, Shanshan Wang, Yan Lu, Lei Chen, Yizhen Mao, Hongwei Ling, Xingbo Cheng, Xiaoyan Zhou
Arch Med Sci 2019;15(3):730-737
BASIC RESEARCH
Dehydrocostus lactone inhibits in vitro gastrinoma cancer cell growth through apoptosis induction, sub-G1 cell cycle arrest, DNA damage and loss of mitochondrial membrane potential
Hou-yong Long, Qing-xian Huang, Yong-yang Yu, Zhen-bin Zhang, Zeng-wu Yao, Hong-bing Chen, Jun-wei Feng
Arch Med Sci 2019;15(3):765-773
EXPERIMENTAL RESEARCH
Minocycline impedes mitochondrial-dependent cell death and stabilizes expression of hypoxia inducible factor-1α in spinal cord injury
Arch Med Sci 2019;15(2):475-483
EXPERIMENTAL RESEARCH
Neuroprotective effects of the new Na channel blocker rs100642 in global ischemic brain injury
Suat Kamisli, Cenk Basaran, Kadir Batcioglu, Mustafa Namık Oztanir, Mehmet Gul, Basri Satilmis, Ayse Burcin Uyumlu, Basak Kayhan, Metin Genc
Arch Med Sci 2019;15(2):467-474
CLINICAL RESEARCH
Age at onset of obesity, transcription factor 7-like 2 (TCF7L2) rs7903146 polymorphism, adiponectin levels and the risk of type 2 diabetes in obese patients
Arch Med Sci 2019;15(2):321-329
BASIC RESEARCH
Renin-angiotensin system inhibitor attenuates oxidative stress induced human coronary artery endothelial cell dysfunction via the PI3K/AKT/mTOR pathway
Arch Med Sci 2019;15(1):152-164
BASIC RESEARCH
Trichostatin A activates FOXO1 and induces autophagy in osteosarcoma
Yunjuan Bai, Yun Chen, Xiaochen Chen, Jiukun Jiang, Xiao Wang, Liping Wang, Jigang Wang, Jianbin Zhang, Liang Gao
Arch Med Sci 2019;15(1):204-213
EXPERIMENTAL RESEARCH
In vivo administration of quercetin ameliorates sperm oxidative stress, inflammation, preserves sperm morphology and functions in streptozotocin-nicotinamide induced adult male diabetic rats
Arch Med Sci 2019;15(1):240-249
CLINICAL RESEARCH
Association of common polymorphisms in the VEGFA and SIRT1 genes with type 2 diabetes-related traits in Mexicans
Armando Totomoch-Serra, Maria de Lourdes Muñoz, Juan Burgueño, Maria Cristina Revilla-Monsalve, Alvaro Diaz-Badillo
Arch Med Sci 2018;14(6):1361-1373
BASIC RESEARCH
PAQR3 inhibits proliferation via suppressing PI3K/AKT signaling pathway in non-small cell lung cancer
Arch Med Sci 2018;14(6):1289-1297
EXPERIMENTAL RESEARCH
Connexin 43 expression in the testes during postnatal development of finasteride-treated male rat offspring
Agnieszka Kolasa-Wołosiuk, Kamila Misiakiewicz-Has, Irena Baranowska-Bosiacka, Izabela Gutowska, Maciej Tarnowski, Marta Tkacz, Barbara Wiszniewska
Arch Med Sci 2018;14(6):1471-1479
BASIC RESEARCH
MicroRNA-590-5p represses proliferation of human fetal airway smooth muscle cells by targeting signal transducer and activator of transcription 3
Arch Med Sci 2018;14(5):1093-1100
BASIC RESEARCH
Analysis of differentially expressed microRNA of TNF-α-stimulated mesenchymal stem cells and exosomes from their culture supernatant
Arch Med Sci 2018;14(5):1102-1111
SYSTEMATIC REVIEW/META-ANALYSIS
Probiotics for management of infantile colic: a systematic review of randomized controlled trials
Arch Med Sci 2018;14(5):1137-1143
CLINICAL RESEARCH
Diagnostic investigation of breast magnetic resonance imaging in malignant and benign mass lesions
Arch Med Sci 2018;14(5):1061-1069
CLINICAL RESEARCH
Association of extrapituitary prolactin promoter polymorphism with disease susceptibility and anti-RNP antibodies in Mexican patients with systemic lupus erythematosus
Jorge Hernández-Bello, Claudia A. Palafox-Sanchez, Samuel García-Arellano, Zyanya Reyes-Castillo, Ana L. Pereira-Suárez, Isela Parra-Rojas, José E. Navarro-Zarza, Ulises De la cruz-Mosso, Nora M. Torres-Carrillo, José Francisco Muñoz-Valle
Arch Med Sci 2018;14(5):1025-1032
BASIC RESEARCH
miR-181b inhibits chemoresistance in cisplatin-resistant H446 small cell lung cancer cells by targeting Bcl-2
Arch Med Sci 2018;14(4):745-751
STATE OF THE ART PAPER
2D and 3D cell cultures – a comparison of different types of cancer cell cultures
Marta Kapałczyńska, Tomasz Kolenda, Weronika Przybyła, Maria Zajączkowska, Anna Teresiak, Violetta Filas, Matthew Ibbs, Renata Bliźniak, Łukasz Łuczewski, Katarzyna Lamperska
Arch Med Sci 2018;14(4):910-919
EXPERIMENTAL RESEARCH
Pretreatment with obestatin inhibits the development of acetic acid-induced colitis in rats
Aleksandra Matuszyk, Piotr Ceranowicz, Zygmunt Warzecha, Jakub Cieszkowski, Krystyna Gałązka, Joanna Bonior, Jolanta Jaworek, Peter Christopher Konturek, Krzysztof Gil, Artur Dembiński
Arch Med Sci 2018;14(4):920-929
BASIC RESEARCH
MicroRNA-141 inhibits proliferation of gastric cardia adenocarcinoma by targeting MACC1
Arch Med Sci 2018;14(3):588-596
BASIC RESEARCH
Lutein prevents osteoarthritis through Nrf2 activation and downregulation of inflammation
Arch Med Sci 2018;14(3):617-624
BASIC RESEARCH
KLF1 gene and borderline hemoglobin A2 in Saudi population
J. Francis Borgio, Sayed AbdulAzeez, Ahmed M. Al-Muslami, Zaki A. Naserullah, Sana Al-Jarrash, Ahmed M. Al-Suliman, Mohammed S. Al-Madan, Amein K. Al-Ali
Arch Med Sci 2018;14(1):230-236
BASIC RESEARCH
Differential action of polyunsaturated fatty acids and eicosanoids on bleomycin-induced cytotoxicity to neuroblastoma cells and lymphocytes
Arch Med Sci 2018;14(1):207-229
CLINICAL RESEARCH
GABRG2 C588T gene polymorphisms might be a predictive genetic marker of febrile seizures and generalized recurrent seizures: a case-control study in a Romanian pediatric population
Anamaria Todoran Butilă, Ancuta Zazgyva, Anca Ileana Sin, Elisabeta Racoș Szabo, Mariana Cornelia Tilinca
Arch Med Sci 2018;14(1):157-166
CLINICAL RESEARCH
MGMT promoter methylation as a potential prognostic marker for acute leukemia
Dominika Sobieszkoda, Joanna Czech, Natalia Gablo, Marta Kopanska, Jacek Tabarkiewicz, Agnieszka Kolacinska, Tadeusz Robak, Izabela Zawlik
Arch Med Sci 2017;13(6):1433-1441
BASIC RESEARCH
Up-regulation of the long non-coding RNA RMRP contributes to glioma progression and promotes glioma cell proliferation and invasion
Arch Med Sci 2017;13(6):1315-1321
BASIC RESEARCH
Value of CNRIP1 promoter methylation in colorectal cancer screening and prognosis assessment and its influence on the activity of cancer cells
Ting Zhang, Ge Cui, Yun-Liang Yao, Qi-Chun Wang, Hong-Guang Gu, Xi-Ning Li, Hui Zhang, Wen-Ming Feng, Qi-Lin Shi, Weiwei Cui
Arch Med Sci 2017;13(6):1281-1294
BASIC RESEARCH
Down-regulation of microRNA-182 and microRNA-183 predicts progression of osteosarcoma
Mohammad Reza Golbakhsh, Bahram Boddouhi, Negin Hatami, Peyman Karimi Goudarzi, Mohammadreza Shakeri, Emad Yahaghi, Afshin Taheriazam
Arch Med Sci 2017;13(6):1352-1356
BASIC RESEARCH
Prognostic implications of phosphatidylinositol 3-kinase/AKT signaling pathway activation in gastric carcinomas
Paula Blandina Ola Chiappini, Ivan Ucella Dantas de Medeiros, Luiz Guilherme Cenaglia Lima, Jose Humberto Fregnani, Suely Nonogaki, Wilson Luiz da Costa Jr, Felipe Jose Fernandez Coimbra, Milton Jose de Barros e Silva, Celso Abdon Lopes de Mello, Clovis Antonio Lopes Pinto, Maria Dirlei Begnami
Arch Med Sci 2017;13(6):1262-1268
BASIC RESEARCH
Investigation of platinum nanoparticle properties against U87 glioblastoma multiforme
Marta Kutwin, Ewa Sawosz, Slawomir Jaworski, Mateusz Hinzmann, Mateusz Wierzbicki, Anna Hotowy, Marta Grodzik, Anna Winnicka, Andre Chwalibog
Arch Med Sci 2017;13(6):1322-1334
BASIC RESEARCH
Functions of the AP-2α gene in activating apoptosis and inhibiting proliferation of gastric cancer cells both in vitro and in vivo
Changqing Zeng, Zhimin Liu, Jian Zhang, Hongwei Fang, Cheng Fang, Yueming Wang, Sharvesh Raj Seeruttun, Jun Chen, Liangxiang Huang, Wei Wang
Arch Med Sci 2017;13(6):1255-1261
STATE OF THE ART PAPER
MicroRNAs and metabolic disorders – where are we heading?
Arch Med Sci 2017;13(4):885-896
CLINICAL RESEARCH
Clinical implications of plasma Nogo-A levels in patients with coronary heart disease
Arch Med Sci 2017;13(4):771-777
CLINICAL RESEARCH
Association between telomere length and complete blood count in US adults
Arch Med Sci 2017;13(3):601-605
CLINICAL RESEARCH
Decreased activity of butyrylcholinesterase in blood plasma of patients with chronic obstructive pulmonary disease
Paulina Sicinska, Bozena Bukowska, Aneta Pajak, Aneta Koceva-Chyla, Tadeusz Pietras, Piotr Nizinkowski, Paweł Gorski, Maria Koter-Michalak
Arch Med Sci 2017;13(3):645-651
BASIC RESEARCH
Neutrophil elastase stimulates MUC5AC expression in human biliary epithelial cells: a possible pathway of PKC/Nox/ROS
Arch Med Sci 2017;13(3):677-685
EXPERIMENTAL RESEARCH
Cardiomyocyte mitochondria as targets of humoral factors released by remote ischemic preconditioning
Nilguen Gedik, Leonardo Maciel, Christiane Schulte, Andreas Skyschally, Gerd Heusch, Petra Kleinbongard
Arch Med Sci 2017;13(2):448-458
EXPERIMENTAL RESEARCH
Stimulation of β-adrenergic receptors plays a protective role via increased expression of RAF-1 and PDX-1 in hyperglycemic rat pancreatic islet (RIN-m5F) cells
Arch Med Sci 2017;13(2):470-480
BASIC RESEARCH
Induction of mitochondrial apoptotic pathway by raloxifene and estrogen in human endometrial stromal ThESC cell line
Ivana Nikolic, Marija Andjelkovic, Milan Zaric, Ivanka Zelen, Petar Canovic, Zoran Milosavljevic, Marina Mitrovic
Arch Med Sci 2017;13(2):293-301
CLINICAL RESEARCH
The association of telomere length and serum 25-hydroxyvitamin D levels in US adults: the National Health and Nutrition Examination Survey
Arch Med Sci 2017;13(1):61-65
BASIC RESEARCH
Serum of obstructive sleep apnea patients impairs human coronary endothelial cell migration
Arch Med Sci 2017;13(1):223-227
STATE OF THE ART PAPER
Exosomes as nanocarriers for siRNA delivery: paradigms and challenges
Arch Med Sci 2016;12(6):1324-1326
CLINICAL RESEARCH
The impact of ACE gene polymorphism on the incidence and phenotype of sarcoidosis in rural and urban settings
Robert Kieszko, Paweł Krawczyk, Tomasz Powrózek, Aneta Szudy-Szczyrek, Michał Szczyrek, Iwona Homa, Jadwiga Daniluk, Janusz Milanowski
Arch Med Sci 2016;12(6):1263-1272
BASIC RESEARCH
Expression of candidate genes associated with obesity in peripheral white blood cells of Mexican children
Marcela Ulloa-Martínez, Ana I. Burguete-García, Selvasankar Murugesan, Carlos Hoyo-Vadillo, Miguel Cruz-Lopez, Jaime García-Mena
Arch Med Sci 2016;12(5):968-976
EXPERIMENTAL RESEARCH
Effect of feeding a high-fat diet independently of caloric intake on reproductive function in diet-induced obese female rats
Arch Med Sci 2016;12(4):906-914
BASIC RESEARCH
Silencing expression of the NANOG gene and changes in migration and metastasis of urinary bladder cancer cells
Arch Med Sci 2016;12(4):889-897
EXPERIMENTAL RESEARCH
Regulation of expression level of fms-like tyrosine kinase-4 is related to osteoclast differentiation
Arch Med Sci 2016;12(3):502-506
EXPERIMENTAL RESEARCH
Exendin-4 enhances expression of Neurod1 and Glut2 in insulin-producing cells derived from mouse embryonic stem cells
Arch Med Sci 2016;12(1):199-207
STATE OF THE ART PAPER
The influence of hypoxic physical activity on cfDNA as a new marker of vascular inflammation
Andrzej Pokrywka, Agnieszka Zembron-Lacny, Katarzyna Baldy-Chudzik, Joanna Orysiak, Dariusz Sitkowski, Maciej Banach
Arch Med Sci 2015;11(6):1156-1163
BASIC RESEARCH
Induction of growth arrest in colorectal cancer cells by cold plasma and gold nanoparticles
Arch Med Sci 2015;11(6):1286-1295
BASIC RESEARCH
The effect of electromagnetic radiation emitted by display screens on cell oxygen metabolism – in vitro studies
Małgorzata Lewicka, Gabriela A. Henrykowska, Krzysztof Pacholski, Janusz Śmigielski, Maciej Rutkowski, Maria Dziedziczak-Buczyńska, Andrzej Buczyński
Arch Med Sci 2015;11(6):1330-1339
BASIC RESEARCH
Apelin-13 protects the heart against ischemia-reperfusion injury through the RISK-GSK-3β-mPTP pathway
Arch Med Sci 2015;11(5):1065-1073
EXPERIMENTAL RESEARCH
Melatonin is more effective than ascorbic acid and β-carotene in improvement of gastric mucosal damage induced by intensive stress
Arch Med Sci 2015;11(5):1129-1136
CLINICAL RESEARCH
A retrospective study of antihypertensives in pemphigus: a still unchartered odyssey particularly between thiols, amides and phenols
Arch Med Sci 2015;11(5):1021-1027
Basic research
Apolipoprotein E polymorphism is associated with susceptibility to schizophrenia among Saudis
Arch Med Sci 2015;11(4):869-876
Clinical research
The roles of connective tissue growth factor in the development of anastomotic esophageal strictures
Arch Med Sci 2015;11(4):770-778
Basic research
Influence of different intensities of vibration on proliferation and differentiation of human periodontal ligament stem cells
Arch Med Sci 2015;11(3):638-646
Clinical research
Association of the Alu insertion polymorphism in the progesterone receptor gene with breast cancer in a Mexican population
Martha Patricia Gallegos-Arreola, Luis E. Figuera, Liliana Gómez Flores-Ramos, Ana María Puebla-Pérez, Guillermo Moisés Zúńiga-González
Arch Med Sci 2015;11(3):551-560
Basic research
Angiotensin II suppresses osteoblastic differentiation and mineralized nodule formation via AT1 receptor in ROS17/2.8 cells
Kumiko Nakai, Takayuki Kawato, Toyoko Morita, Yoji Yamazaki, Hideki Tanaka, Morio Tonogi, Hidero Oki, Masao Maeno
Arch Med Sci 2015;11(3):628-637
Experimental research
Protective effect of melatonin against zonisamide-induced reproductive disorders in male rats
Arch Med Sci 2015;11(3):660-669
Basic research
Efficacy of low dose temozolomide in combination with bortezomib in U87 glioma cells: a flow cytometric analysis
Arch Med Sci 2015;11(2):307-310
Experimental research
Quercetin protects against lipopolysaccharide-induced acute lung injury in rats through suppression of inflammation and oxidative stress
Arch Med Sci 2015;11(2):427-432
State of the art paper
Platelet-derived growth factors induced lymphangiogenesis: evidence, unanswered questions and upcoming challenges
Arch Med Sci 2015;11(1):57-66
Clinical research
One-step nucleic acid amplification testing in medullary thyroid cancer lymph nodes: a case series
Krzysztof Kaczka, Wojciech Fendler, Maciej Borowiec, Wojciech Młynarski, Katarzyna Paduszynska, Anna Grzegory, Lech Pomorski
Arch Med Sci 2015;11(1):137-141
Evaluation of the protective effect of Nigella sativa extract and its primary active component thymoquinone against DMBA-induced breast cancer in female rats
Arch Med Sci 2015;11(1):220-229
Basic research
BDNF and HSP gene polymorphisms and their influence on the progression of primary open-angle glaucoma in a Polish population
Alicja Nowak, Jacek P. Szaflik, Mira Gacek, Karolina Przybylowska-Sygut, Anna Kamińska, Jerzy Szaflik, Ireneusz Majsterek
Arch Med Sci 2014;10(6):1206-1213
Basic research
Association study of COX-2 (PTGS2) –765 G/C promoter polymorphism by pyrosequencing in Sicilian patients with Alzheimer’s disease
Arch Med Sci 2014;10(6):1235-1238
Basic research
The association between the 844ins68 polymorphism in the CBS gene and breast cancer
Martha Patricia Gallegos-Arreola, Luis Eduardo Figuera-Villanueva, Adriana Ramos-Silva, Efraín Salas-González, Ana María Puebla-Pérez, Valeria Peralta-Leal, José Elías García-Ortiz, Ingrid Patricia Dávalos-Rodríguez, Guillermo Moisés Zúńiga-González
Arch Med Sci 2014;10(6):1214-1224
Clinical research
Peripheral blood lymphocyte subsets (CD4+, CD8+ T cells), leptin level and weight loss after laparoscopic greater curvature plication in morbidly obese patients
Arch Med Sci 2014;10(5):886-890
Experimental research
Effects of ghrelin on protein expression of antioxidative enzymes and iNOS in the rat liver
Branislava Dobutovic, Emina Sudar, Snezana Tepavcevic, Jelena Djordjevic, Ana Djordjevic, Marija Radojcic, Esma R. Isenovic
Arch Med Sci 2014;10(4):806-816
Basic research
Radiosensitivity of human ovarian carcinoma and melanoma cells to γ-rays and protons
Otilija Keta, Danijela Todorović, Nataša Popović, Lela Korićanac, Giacomo Cuttone, Ivan Petrović, Aleksandra Ristić-Fira
Arch Med Sci 2014;10(3):578-586
Basic research
Impact of adipogenic differentiation on stemness and osteogenic gene expression in extensive culture of human adipose-derived stem cells
Arch Med Sci 2014;10(3):597-606
Experimental study
Improved methodology to obtain large quantities of correctly folded recombinant N-terminal extracellular domain of the human muscle acetylcholine receptor for inducing experimental autoimmune myasthenia gravis in rats
Arch Med Sci 2014;10(2):389-395
Basic research
Effects of natural honey on polymicrobial culture of various human pathogens
Noori S. Al-Waili, Faiza S. Al-Waili, Mohammed Akmal, Amjed Ali, Khelod Y. Salom, Ahmad A. Al Ghamdi
Arch Med Sci 2014;10(2):246-250
Experimental research
Effects of intravenous human umbilical cord blood CD34+ stem cell therapy versus levodopa
Arch Med Sci 2013;9(6):1138-1151
Basic research
Vitamin C modulates DNA damage induced by hydrogen peroxide in human colorectal adenocarcinoma cell lines (HT29) estimated by comet assay in vitro
Arch Med Sci 2013;9(6):1006-1012
Basic research
CXCL12-G801A polymorphism modulates risk of colorectal cancer in Taiwan
Arch Med Sci 2013;9(6):999-1005
Basic research
Mutation spectrum of GATA4 associated
with congenital atrial septal defects
Arch Med Sci 2013;9(6):976-983
Basic research
Association of temporomandibular dysfunction with the 102T-C polymorphism in the serotonin receptor gene in Brazilian patients
Luciana Venâncio Secches de Freitas, Ana Cláudia Polli Lopes, Vânia Belintani Piatto, José Victor Maniglia
Arch Med Sci 2013;9(6):1013-1018
Clinical research
Evaluation of TGF-β1, CCL5/RANTES and sFas/Apo-1 urine concentration in children with ureteropelvic junction obstruction
Arch Med Sci 2013;9(5):888-894
Evaluation and identification of damaged single nucleotide polymorphisms in COL1A1 gene involved in osteoporosis
Arch Med Sci 2013;9(5):899-905
Basic research
Association of Epstein-Barr virus infection and breast carcinoma
Arch Med Sci 2013;9(4):745-751
Basic research
Influence of L-arginine on expression of HSP70 and p-53 proteins – early biomarkers of cellular danger in renal tubular cells. Immunohistochemical assessment
Arch Med Sci 2013;9(4):719-723
Basic research
Expression of IL-7 receptor in human peripheral regulatory T cells
Arch Med Sci 2013;9(3):555-560
Basic research
Valproic acid upregulates NKG2D ligand expression and enhances susceptibility of human renal carcinoma cells to NK cell-mediated cytotoxicity
Fengqiang Yang, Yang Shao, Fengping Yang, Ming Liu, Jianhua Huang, Kai Zhu, Changcheng Guo, Jun Luo, Wei Li, Bin Yang, Jumei Shi, Junhua Zheng
Arch Med Sci 2013;9(2):323-331
Basic research
Adenovirus-mediated RAR-β over-expression enhances ATRA-induced neuronal differentiation of rat mesenchymal stem cells
Arch Med Sci 2013;9(2):314-322
Experimental research
Maturational changes in connexin 43 expression in the seminiferous tubules may depend on thyroid hormone action
Katarzyna Marchlewska, Krzysztof Kula, Renata Walczak-Jedrzejowska, Wojciech Kula, Elzbieta Oszukowska, Eliza Filipiak, Tomasz Moszura, Jolanta Slowikowska-Hilczer
Arch Med Sci 2013;9(1):139-145
State of the art paper
The role of G protein coupled receptor kinases in neurocardiovascular pathophysiology
Arch Med Sci 2012;8(6):970-977
Basic research
Antimicrobial susceptibility and genetic similarity of ESBL-positive Klebsiella pneumoniae strains
Arch Med Sci 2012;8(6):993-997
Clinical research
Polymorphism of the DNA repair genes RAD51 and XRCC2 in smoking- and drinking-related laryngeal cancer in a Polish population
Hanna Romanowicz-Makowska, Beata Smolarz, Marzena Gajęcka, Katarzyna Kiwerska, Malgorzata Rydzanicz, Dariusz Kaczmarczyk, Jurek Olszewski, Krzysztof Szyfter, Janusz Błasiak, Alina Morawiec-Sztandera
Arch Med Sci 2012;8(6):1065-1075
Basic research
Expression of selected human endogenous retroviral sequences in skin and peripheral blood mononuclear cells in morphea
Michał J. Kowalczyk, Aleksandra Dańczak-Pazdrowska, Beata Szramka-Pawlak, Ryszard Żaba, Wojciech Silny, Agnieszka Osmola-Mańkowska
Arch Med Sci 2012;8(5):819-825
Clinical research
Evaluation of glutathione S-transferase P1 genetic variants affecting type-2 diabetes susceptibility and glycemic control
Arch Med Sci 2012;8(4):631-636
Basic research
Up-regulated osteogenic transcription factors during early response of human periodontal ligament stem cells to cyclic tensile strain
Arch Med Sci 2012;8(3):422-430
Basic research
β-Thalassemia mutations and hemoglobinopathies in Adana, Turkey: results from a single center study
Birol Guvenc, Abdullah Canataroglu, Cagatay Unsal, Sule Menziletoglu Yildiz, Ferda Tekin Turhan, Sevcan Tug Bozdogan, Suleyman Dincer, Hakan Erkman
Arch Med Sci 2012;8(3):411-414
Basic research
Bioinformatics characterization of differential proteins in serum of mothers carrying Down syndrome fetuses: combining bioinformatics and ELISA
Arch Med Sci 2012;8(2):183-191
Basic research
Age-related BMAL1 change affects mouse bone marrow stromal cell proliferation and osteo-differentiation potential
Arch Med Sci 2012;8(1):30-38
Basic research
Age- and sex-dependent mRNA expression of KCNQ1 and HERG in patients with long QT syndrome type 1 and 2
Ewa Moric-Janiszewska, Joanna Głogowska-Ligus, Monika Paul-Samojedny, Ludmiła Węglarz, Grażyna Markiewicz-Łoskot, Lesław Szydłowski
Arch Med Sci 2011;7(6):941-947
Basic research
Modulation of collagen synthesis and its gene expression in human skin fibroblasts by tocotrienol-rich fraction
Arch Med Sci 2011;7(5):889-895
Clinical research
Cigarette smoking induces overexpression of c-Met receptor in microvessels of oral lichen planus
Arch Med Sci 2011;7(4):706-712
Basic research
Detection of 1311 polymorphism in the glucose-6-phosphate dehydrogenase gene by microarray technique
Arch Med Sci 2011;7(4):586-591
Basic research
Carboxylic acid derivatives of histone deacetylase inhibitors induce full length SMN2 transcripts: a promising target for spinal muscular atrophy therapeutics
Arch Med Sci 2011;7(2):230-234
Basic research
Effect of FDC-SP on the phenotype expression of cultured periodontal ligament cells
Arch Med Sci 2011;7(2):235-241
Clinical research
Hypertonic saline solutions do not influence the solubility of sputum from secretor and non-secretor cystic fibrosis patients
Marcelo A.I. Barboza, Cinara C. Brandão de Mattos, Ana Iara C. Ferreira, Paulo R. Barja, Newton Santos de Faria Junior, Luís Vicente F. de Oliveira, Luiz C. de Mattos
Arch Med Sci 2011;7(2):326-331
Basic research
Effects of ibandronate-hydroxyapatite on resorptive activity of osteoclasts
Arch Med Sci 2011;7(1):53-60
Clinical research
The 844ins68 cystathionine beta-synthase and C677T MTHFR gene polymorphism and the vaso-occlusive event risk in sickle cell disease
Arch Med Sci 2011;7(1):97-101
RESEARCH PAPER
Genetically predicted 1,400 blood metabolites related to the risk of ovarian cancer: A Mendelian randomization study
STATE OF THE ART PAPER
Clinical applications of deep learning in distinguishing Benign from Malignant Pulmonary Nodules in CT Scans
RESEARCH PAPER
The Plasma Metabolite-Mediated Relationship between Inflammatory Cytokines and Acute Respiratory Distress Syndrome
CLINICAL RESEARCH
Risk stratification of soft tissue sarcoma based on activity of prognostic molecules associated with unpolarized macrophages
Editor's Choice
RESEARCH PAPER
Telomere length across the spectrum of metabolic health – an analysis from the LIPIDOGEN2015 study
Maciej Banach, Martyna Fronczek, Anna Goc, Mateusz Lejawa, Ewa Boniewska-Bernacka, Tadeusz Osadnik, Anna Pańczyszyn, Joanna Katarzyna Strzelczyk, Natalia Pawlas, Marek Gierlotka, Marcin Goławski, Karol Krystek, Agnieszka Gach, Kamila Osadnik, Jacek Jóźwiak
CLINICAL RESEARCH
High levels of uric acid upregulate endothelin receptors: the role of MAPK pathways in an in vitro study
Editor's Choice
STATE OF THE ART PAPER
Implications for the role of natural products in Parkinson disease therapy
BASIC RESEARCH
The SP1/SNHG16/GLUT1 axis promotes prostate cancer proliferation and invasion by regulating glucose metabolism
Arch Med Sci 2025;21(2):638-647
RESEARCH LETTER
Efficacy of statin therapy in reducing epicardial adipose tissue: a systematic review and meta-analysis
Tannaz Jamialahmadi, Luis E. Simental-Mendia, Ali H. Eid, Wael Almahmeed, Sepideh Salehabadi, Khalid Al-Rasadi, Maciej Banach, Amirhossein Sahebkar
Arch Med Sci 2024;20(3):997-1001
RESEARCH LETTER
Combretastatin A4 phosphate encapsulated in hyaluronic acid nanoparticles is highly cytotoxic to oral squamous cell carcinoma
Arch Med Sci 2024;20(3):1022-1028
STATE OF THE ART PAPER
Recent advances in immune checkpoint inhibitor-based therapy of advanced hepatocellular carcinoma
CLINICAL RESEARCH
LncRNA KTN1-AS1 drives tumor progression in non-small cell lung cancer through the microRNA-153-3p/KLF5 axis
CLINICAL RESEARCH
YTHDF3-mediated m6A modification facilitates osteosarcoma progression through the FSP1-CoQ10-NAD(P)H axis to suppress ferroptosis
RESEARCH LETTER
Telomeres and telomerase in endometrial cancer and hyperplasia
Arch Med Sci 2024;20(2):682-685
LETTER TO THE EDITOR
Inheritance of Hb S and G6PD deficiency in a familiar group
Arch Med Sci 2024;20(2):704-707
RESEARCH LETTER
Gedunin induces apoptosis and inhibits HMBG1/PI3K/AKT signaling pathways in a rat model of gastric carcinogenesis induced by methylnitronitrosoguanidine
Arch Med Sci 2024;20(2):691-697
RESEARCH LETTER
Insulin-like growth factor-1 reduces cardiac autosis through decreasing AMPK/FOXO1 signaling and Na+/K+-ATPase-Beclin-1 interaction
Arch Med Sci 2024;20(3):1011-1015
CLINICAL RESEARCH
Women suffering from systemic lupus erythematosus are characterized by low blood levels of α-dicarbonyl compounds
Agnieszka Nowak, Brygida Przywara-Chowaniec, Aleksandra Damasiewicz-Bodzek, Beata Janoszka, Magdalena Szumska, Sławomir Waligóra, Krystyna Tyrpień-Golder
Arch Med Sci 2024;20(3):743-750
BASIC RESEARCH
Cinobufagin disrupts the stability of lipid rafts by inhibiting the expression of caveolin-1 to promote non-small cell lung cancer cell apoptosis
Arch Med Sci 2024;20(3):887-908
BASIC RESEARCH
Circular RNA circ_001621 acts as a tumor promoter in lung cancer by regulating the miR-199a-3p/GREM1 axis
Arch Med Sci 2024;20(3):876-886
BASIC RESEARCH
Enhancing postmenopausal osteoporosis: a study of KLF2 transcription factor secretion and PI3K-Akt signaling pathway activation by PIK3CA in bone marrow mesenchymal stem cells
Arch Med Sci 2024;20(3):918-937
BASIC RESEARCH
Analysis of lcnRNAHomebox transcript antisense RNA (HOTAIR) expression in Polish women with endometriosis
Arch Med Sci 2025;21(2):688-694
CLINICAL RESEARCH
Levels of small extracellular vesicles in patients treated with hyperbaric oxygenation
Jacek Siewiera, Michał Smoleński, Natalia Jermakow, Jacek Kot, Torsten E. Reichert, Piotr Miśkiewicz, Łukasz Zaręba, Anna Cyran, Mirosław J. Szczepański, Nils Ludwig
Arch Med Sci 2024;20(2):476-484
RESEARCH PAPER
miR-10b-5p regulates venous endothelial cells in deep venous thrombosis by targeting MFG-E8
RESEARCH PAPER
Galectin-3 regulates skeletal muscle loss via TGFβ1-Smad2/3 signaling activation in mice
RESEARCH PAPER
Metformin attenuates the progression of esophageal squamous cell carcinoma by downregulating miR-141-3p to enhance SCEL
SYSTEMATIC REVIEW/META-ANALYSIS
Association of the IL-4R Q576R polymorphism with asthma: a meta-analysis
RESEARCH PAPER
ADPKD protects against diabetogenic effects associated with genetically-predicted lactase persistence.
Maria Pietrzak-Nowacka, Krzysztof Safranow, Agnieszka Boroń, Małgorzata Ryder-Woźniak, Kazimierz Ciechanowski, Ciechanowicz Andrzej
STATE OF THE ART PAPER
Transcatheter arterial chemoembolization and radiofrequency ablation combined with immunotherapy for hepatocellular carcinoma patients
RESEARCH PAPER
Acetyl-L-carnitine protects against LPS induced depression via PPAR-γ induced inhibition of NF-κB/NLRP3 pathway
Amna Samin, Lina Tariq Al Kury, Shabir Hussain, Muhammad Imran Khan, Abdullah Alattar, Reem Alshaman, Fawad Ali Shah, Muhammad Aamir, Shupeng Li
EXPERIMENTAL RESEARCH
Preparation, characterization and investigation of the anti-human ovarian cancer activity of silver nanoparticles green-formulated by Salvia officinalis leaf aqueous extract
RESEARCH PAPER
Incidence of breast cancer and methylation of PCDH gene: a single ratio meta analysis of single rate
Yu Liu, lili zhong, lixing wang, duohan zhang, chao zhang, xiaoliang xiong, tingting hao, yinlong zhao
EXPERIMENTAL RESEARCH
Iron nanoparticles green-formulated by Coriandrum sativum leaf aqueous extract: investigation of its anti-liver-cancer effects
EXPERIMENTAL RESEARCH
Green formulation and characterization of Fe nanoparticles containing Calendula extract and investigation of the antioxidant, cytotoxic and anti-human cholangiocarcinoma properties
EXPERIMENTAL RESEARCH
Intestinal flora imbalance affects the prognosis of Parkinson’s disease by regulating the expression of fecal microRNA-146a and GDNF: a preliminary study
RESEARCH PAPER
Proapoptotic protein Smac mediates apoptosis in ovarian cancer cells when treated with carpachromene
RESEARCH PAPER
Tiliroside: anti-liver cancer effects and investigation of aldose reductase inhibition properties with molecular modeling studies
RESEARCH PAPER
H2S treatment improves protective effect of mesenchymal stem cell-derived exosomes on renal ischemia/reperfusion fibrosis by suppressing inflammatory signaling of TGF-β and NF-κB as well as radical oxygen species generation
Ya-Peng Wang, Rui-Xiao Wang, Zhao-Jun Li, Xue-Yi Wang, Xia Qiao, Tao Ma, Zong-Ying Jiang, Ling-Ya Huang
BASIC RESEARCH
Anti-leukemia properties of cadmium nanoparticles in in vitro and in vivo conditions: a chemobiological study
RESEARCH PAPER
Calendula officinalis green-mediated silver nanoparticles: formulation, characterization and assessment of colorectal cancer activities
Yongchao Xu, Behnam Mahdavi, Mohammad Mahdi Zangeneh, Akram Zangeneh, Maryam Qorbani, Sogand Paydarfard
BASIC RESEARCH
Novel formulation, cytotoxicity, antioxidant, and anti-human lung cancer properties of gold nanoparticles containing Verbascum thapsus L. leaf aqueous extract
Kaijin Lu, Yan Ou, Lihao Jiang, Yijia Xiao, Arunachalam Chinnathambi, Tahani Awad Alahmadi, Milton Wainwright
BASIC RESEARCH
Anti-human ovarian cancer, cytotoxicity, and antioxidant effects of Nigella sativa green-formulated Au nanoparticles: describing a new chemotherapeutic supplement
Haibo Ruan, Li Wang, Minyuan Wang, Weiwei Mo, Jichao Jin, Arunachalam Chinnathambi, Tahani Awad Alahmadi, Velmurugan Meganathan, Ling Zhang
RESEARCH PAPER
Genetic factors that may affect the risk of developing thrombosis in patients with myeloproliferative disorders
Roberta Vadeikienė, Monika Kurgonaitė, Rūta Dambrauskienė, Rasa Ugenskienė, Rolandas Gerbutavičius, Elona Juozaitytė
EXPERIMENTAL RESEARCH
An immune-related long non-coding RNA signature predicts prognosis in glioblastoma patients
EXPERIMENTAL RESEARCH
Overexpression of miR-221-3p affects cell proliferation, apoptosis and inflammation by targeting toll-like receptor 4 in propofol-induced rat astrocytes
BASIC RESEARCH
Anti-small cell lung cancer and collagenase inhibition properties of hydroxysafflor yellow A
RESEARCH PAPER
Gentiana macrophylla exhibits a potential therapeutic effect on osteoarthritis (OA) via modulating disease-related proteins
RESEARCH PAPER
Adenosine A2a Receptors Improve Hypoxic Pulmonary Arterial Hypertension Via Mitochondrial ATP-sensitive Potassium Channels
Lihuang Su, Gexiang Cai, Lin Zhang, Zhimin Cui, Lin Yang, Junwei Sun, Luqiong Cai, Lehe Yang, Xiaomei Xu, Liangxing Wang, Xiaoying Huang
RESEARCH PAPER
Melatonin Enhances Chondrocytes Survival Through Hyaluronic Acid Production and Mitochondria Protection
Zhi-Qiang Liu, Jingjing Wang, Amrish Thapa, Ying Xie, Jing Guo, Xin Li, Hongmei Jiang, Yixuan Wang, Ziyi Peng, Sheng Wang, Jingya Wang, Xianhui Li, Lingqun Ye
CLINICAL RESEARCH
A pre-clinical trial study on afzelin: anti-human lung cancer, anti-cholinesterase, and anti-glucosidase properties
BASIC RESEARCH
Identification of natural compounds (proanthocyanidin and rhapontin) as high-affinity inhibitors of SARS-CoV-2 Mpro and PLpro using computational strategies
Arch Med Sci 2024;20(2):567-581
CLINICAL RESEARCH
Dihydromyricetin alleviates endothelial inflammatory response through the IRE1α/NF-κB signaling pathway in sepsis
Xifeng Wang, Xiaomin Xu, Yu Peng Yang, Xin Xin, Zekang Li, Qimeng Wang, Xiaoli Li, Yun Hou, Lianshuang Zhang
RESEARCH PAPER
Ubiquitin specific peptidase 49 inhibits renal fibrosis through protein phosphatase magnesium-dependent1A-mediated Smad2/3 pathway
RESEARCH PAPER
AnnexinA7 and CAP1 are associated with regulating tumor cell adhesion molecule expression and biological behavior
RESEARCH PAPER
Administration of simvastatin halts progression of cirrhosis via up-regulating expression of miR-34a and interleukin-10 in rats
BASIC RESEARCH
LncRNA MIR155HG functions as a ceRNA for inhibition of lung adenocarcinoma growth and prediction of prognosis
Arch Med Sci 2024;20(2):539-556
RESEARCH PAPER
MiR-125b-5p enclosed in hypoxic HK2 cell-derived extracellular vesicles alleviates renal ischemia-reperfusion injury by regulating NLRC5
Kai Xu, Lifeng Zhang, Lei Zhang, Lei Zhang, Ze Zhang, Siwei Qian, Xiangyu Zou, Shuqiu Chen, Li Zuo, ming chen, Guangyuan Zhang
CLINICAL RESEARCH
The prognostic impact of CD49d protein and mRNA expression in patients with chronic lymphocytic leukaemia
Maciej Putowski, Katarzyna Skórka, Monika Włodarczyk, Waldemar Tomczak, Edyta Subocz, Janusz Hałka, Krzysztof Giannopoulos
CLINICAL RESEARCH
Both AA genotype of rs165599 and Val/Val genotype of rs4680 in COMT are associated with an increased risk of recurrence of prostate cancer
EXPERIMENTAL RESEARCH
Inhibition of histone deacetylase promotes a neuroprotective mechanism in an experimental model of Parkinson’s disease
Arch Med Sci 2024;20(2):664-674
RESEARCH PAPER
Lycopene prevents cisplatin-induced liver tissue damage, without affecting concentrations of TNF-α or iNOS/NO inflammatory pathway
Aleksandar Rankovic, Vanja Nickovic, Tanja Novakovic, Nebojsa Mitic, Biljana Krdzic, Jadranka Mitic, Gordana Nikolic, Dusan T Sokolovic
RESEARCH PAPER
Lipotoxicity induced pancreatic beta cell damage is associated with GPR119/MST1/FoxO1 Pathway
Lirong Ma, Jianning Li, Hui Song, Yan Li, Yue Wang, Yansong Luan, Yuhan Li, Hui Qi, Yi Yang, Lei Cai
RESEARCH PAPER
Up-regulation of peroxiredoxin 3 by high-risk human papillomavirus in cervical cancer cells
RESEARCH PAPER
CircRNA LRIG3 knockdown inhibits hepatocellular carcinoma progression by regulating miR-223-3p and MAPK/ERK pathway
BASIC RESEARCH
miR-338-3p attenuates oxaliplatin resistance in gastric cancer cells via targeting thrombospondin-1
EXPERIMENTAL RESEARCH
Expression pattern of circulating long non-coding RNA GAS5 as a novel biomarker in non-small cell lung cancer patients
Natasa Vesovic, Natasa Tosic, Teodora Karan Djurasevic, Zoran Andric, Darko Zdravkovic, Sonja Pavlovic, Dragana Jovanovic
CLINICAL RESEARCH
Association of genetic polymorphisms on methotrexate toxicity in patients with rheumatoid arthritis
María José Zarzuelo Romero, María del Mar Maldonado Montoro, Cristina Pérez Ramírez, Noelia Márquez Pete, Almudena Sánchez Martín, Fernando Martínez Martínez, Miguel Ángel Calleja Hernández, María Carmen Ramírez Tortosa, Alberto Jiménez Morales
RESEARCH PAPER
Amplification of Cord Blood-Derived Cytotoxic T Lymphocytes using HL-60 cell Derived Exosomes
EXPERIMENTAL RESEARCH
The anti-lung cancer effect of ethyl acetate extract from Wenxia Formula in vivo via the Hedgehog-Gli1 signaling pathway mediated by cancer associated fibroblasts
CLINICAL RESEARCH