Topic Biology, Molecular
STATE OF THE ART PAPER
Genetic syndromes with vascular malformations – update on molecular background and diagnostics
Adam Ustaszewski, Joanna Janowska-Głowacka, Katarzyna Wołyńska, Anna Pietrzak, Magdalena Badura-Stronka
Arch Med Sci 2021;17(4):965–991
BASIC RESEARCH
Long intergenic non-coding RNA, regulator of reprogramming (LINC-ROR) over-expression predicts poor prognosis in renal cell carcinoma
Arch Med Sci 2021;17(4):1016–1027
STATE OF THE ART PAPER
The role of vitamin D in perinatology. An up-to-date review
Michał Ciebiera, Cezary Wojtyła, Krzysztof Łukaszuk, Magdalena Zgliczyńska, Kornelia Zaręba, Wojciech Rawski, Grzegorz Jakiel
Arch Med Sci 2021;17(4):992–1005
BASIC RESEARCH
Haemoglobin switching modulator SNPs rs5006884 is associated with increased HbA2 in β-thalassaemia carriers
Cyril Cyrus, Chittibabu Vatte, Shahanas Chathoth, Abdul Azeez Sayed, J. Francis Borgio, Mohammed Abdullah Alrubaish, Rawan Alfalah, Jana Alsaikhan, Amein K. Al Ali
Arch Med Sci 2021;17(4):1064–1074
RESEARCH LETTER
Serological testing for SARS-CoV-2 in Bosnia and Herzegovina: first report
Adna Ašić, Jasminka Prguda-Mujić, Lana Salihefendić, Larisa Bešić, Daria Ler, Ivana Čeko, Almira Hadžović-Džuvo, Sead Jažić, Rijad Konjhodžić, Damir Marjanović
Arch Med Sci 2021;17(3):823–826
BASIC RESEARCH
Modulation of Ki67 and myogenic regulatory factor expression by tocotrienol-rich fraction ameliorates myogenic program of senescent human myoblasts
Chun Min Tan, Nadwa Aqeela Mohd Najib, Nur Farahin Suhaimi, Nur Alia Halid, Vi Vien Cho, Saiful Idham Abdullah, Muhammad Zulhilmi Ismail, Shy Cian Khor, Faizul Jaafar, Suzana Makpol
Arch Med Sci 2021;17(3):752–763
EXPERIMENTAL RESEARCH
Salidroside regulates imbalance of Th17/Treg and promotes ischemic tolerance by targeting STAT-3 in cerebral ischemia-reperfusion injury
Arch Med Sci 2021;17(2):523–534
CLINICAL RESEARCH
Adipokine signatures of subcutaneous and visceral abdominal fat in normal-weight and obese women with different metabolic profiles
Arch Med Sci 2021;17(2):323–336
BASIC RESEARCH
MicroRNA-16 inhibits the lipopolysaccharide-induced inflammatory response in nucleus pulposus cells of the intervertebral disc by targeting TAB3
Arch Med Sci 2021;17(2):500–513
EXPERIMENTAL RESEARCH
Up-regulation of autophagy and apoptosis of cochlear hair cells in mouse models for deafness
Arch Med Sci 2021;17(2):535–641
LETTER TO THE EDITOR
Mesenchymal soluble factors confer imatinib drug resistance in chronic myelogenous leukemia cells
Arch Med Sci 2021;17(1):266–274
BASIC RESEARCH
CNTN-1 promotes docetaxel resistance and epithelial-to-mesenchymal transition via the PI3K/Akt signaling pathway in prostate cancer
Arch Med Sci 2021;17(1):152–165
EXPERIMENTAL RESEARCH
Effects of free and nanoparticulate curcumin on chemically induced liver carcinoma in an animal model
Eman Shawky Mohammed, Nadia M. El-Beih, Enas Ali El-Hussieny, Eman El-Ahwany, Marwa Hassan, Mona Zoheiry
Arch Med Sci 2021;17(1):218–227
BASIC RESEARCH
Resveratrol is cytotoxic and acts synergistically with NF-κB inhibition in osteosarcoma MG-63 cells
Arch Med Sci 2021;17(1):166–176
SYSTEMATIC REVIEW/META-ANALYSIS
IFN-γ +874 A>T (rs2430561) gene polymorphism and risk of pulmonary tuberculosis: a meta-analysis
Mohammed Y. Areeshi, Raju K. Mandal, Sajad A. Dar, Arshad Jawed, Mohd Wahid, Mohtashim Lohani, Aditya K. Panda, B. N. Mishra, Naseem Akhter, Shafiul Haque
Arch Med Sci 2021;17(1):177–188
BASIC RESEARCH
Inhibition of miR-22 promotes differentiation of osteoblasts and improves bone formation via the YWHAZ pathway in experimental mice
Arch Med Sci 2020;16(6):1419–1431
BASIC RESEARCH
MSK1 promotes cell proliferation and metastasis in uveal melanoma by phosphorylating CREB
Arch Med Sci 2020;16(5):1176–1188
BASIC RESEARCH
LncRNA PCAT-1 upregulates RAP1A through modulating miR-324-5p and promotes survival in lung cancer
Arch Med Sci 2020;16(5):1196–1206
LETTER TO THE EDITOR
Inverse correlation between levels of glycated haemoglobin and expression levels of SERCA protein in Mexican patients with type 2 diabetes mellitus
Octavio Galindo-Hernandez, Jesus Rene Machado-Contreras, Rodrigo Martinez-Corella, Tatiana Romero-Garcia, J. Gustavo Vazquez-Jimenez
Arch Med Sci 2020;16(5):1226–1228
CLINICAL RESEARCH
Klotho and vitamin D in multiple sclerosis: an Italian study
Concetta Scazzone, Luisa Agnello, Bruna Lo Sasso, Paolo Ragonese, Giulia Bivona, Sabrina Realmuto, Giorgia Iacolino, Caterina Maria Gambino, Chiara Bellia, Giuseppe Salemi, Marcello Ciaccio
Arch Med Sci 2020;16(4):842–847
BASIC RESEARCH
miR-133a-3p promotes apoptosis and induces cell cycle arrest by targeting CREB1 in retinoblastoma
Arch Med Sci 2020;16(4):941–956
LETTER TO THE EDITOR
Arachidonic and eicosapentaenoic acids induce oxidative stress to suppress proliferation of human glioma cells
Arch Med Sci 2020;16(4):974–983
CLINICAL RESEARCH
Association between oxidative stress biomarkers and concentrations of some metal ions in the blood of patients with brain tumors and hydrocephalus
Ljiljana Vujotić, Siniša Matić, Slavica Borković-Mitić, Aleksandar Stojsavljević, Jelena Mutić, Vladimir Baščarević, Miloš Joković, Slađan Pavlović
Arch Med Sci 2020;16(4):811–819
STATE OF THE ART PAPER
Ankyrins in human health and disease – an update of recent experimental findings
Arch Med Sci 2020;16(4):715–726
RESEARCH PAPER
State-of-the-art tools unveil potent drug targets amongst clinically approved drugs to inhibit helicase in SARS-CoV-2
J. Francis Borgio, Hind Saleh Alsuwat, Waad Mohammed Al Otaibi, Abdallah M. Ibrahim, Noor B Almandil, Lubna Ibrahim Al Asoom, Mohammed Salahuddin, Balu Kamaraj, Sayed AbdulAzeez
Arch Med Sci 2020;16(3):508–518
LETTER TO THE EDITOR
Spectrum of ALDH1 mRNA in smokers and non-smokers with adenocarcinoma or squamous cell lung carcinoma
Arch Med Sci 2020;16(3):709–713
BASIC RESEARCH
Long non-coding RNA SNHG1 promotes cell proliferation and invasion of hepatocellular carcinoma by acting as a molecular sponge to modulate miR-195
Arch Med Sci 2020;16(2):386–394
BASIC RESEARCH
Lysyl hydroxylase 3 increases collagen deposition and promotes pulmonary fibrosis by activating TGFβ1/Smad3 and Wnt/β-catenin pathways
Songjun Shao, Haiyan Fang, Lindi Duan, Xianwei Ye, Shanshan Rao, Jin Han, Yumei Li, Guohang Yuan, Weijia Liu, Xiangyan Zhang
Arch Med Sci 2020;16(2):436–445
BASIC RESEARCH
Establishment of stable cell lines in which the HBV genome replicates episomally for evaluation of antivirals
Arch Med Sci 2020;16(2):407–413
BASIC RESEARCH
Anticancer activity of sugiol against ovarian cancer cell line SKOV3 involves mitochondrial apoptosis, cell cycle arrest and blocking of the RAF/MEK/ERK signalling pathway
Arch Med Sci 2020;16(2):428–435
BASIC RESEARCH
Differential effect of adenosine on rhabdomyosarcoma migration and proliferation
Arch Med Sci 2020;16(2):414–427
EXPERIMENTAL RESEARCH
Effect of N-acetylcysteine on intimal hyperplasia and endothelial proliferation in rabbit carotid artery anastomosis
Arch Med Sci 2019;15(6):1576–1581
CLINICAL RESEARCH
MicroRNA-122a as a non-invasive biomarker for HCV genotype 4-related hepatocellular carcinoma in Egyptian patients
Eman G. E. El-Ahwany, Lobna Mourad, Mona M. K. Zoheiry, Hoda Abu-Taleb, Marwa Hassan, Raafat Atta, Moataz Hassanien, Suher Zada
Arch Med Sci 2019;15(6):1454–1461
EXPERIMENTAL RESEARCH
The role of interleukin-6 in intracellular signal transduction after chronic β-adrenergic stimulation in mouse myocardium
Magdalena Dziemidowicz, Tomasz A. Bonda, Siergiej Litvinovich, Andrzej Taranta, Maria M. Winnicka, Karol A. Kamiński
Arch Med Sci 2019;15(6):1565–1575
BASIC RESEARCH
Effects of vascular endothelial growth factor and epidermal growth factor on biological properties of gastric cancer cells
Arch Med Sci 2019;15(6):1498–1509
BASIC RESEARCH
Genes and metabolic pathway of sarcoidosis: identification of key players and risk modifiers
Mihailo I. Stjepanovic, Violeta Mihailovic-Vucinic, Vesna Spasovski, Jelena Milin-Lazovic, Vesna Skodric-Trifunovic, Sanja Stankovic, Marina Andjelkovic, Jovana Komazec, Ana Momcilovic, Milena Santric-Milicevic, Sonja Pavlovic
Arch Med Sci 2019;15(5):1138–1146
BASIC RESEARCH
STAT3 promotes chronic lymphocytic leukemia progression through upregulating SMYD3 expression
Arch Med Sci 2019;15(5):1163–1175
BASIC RESEARCH
Up-regulation of FTO gene expression was associated with increase in skeletal muscle mass in overweight male adolescents
Saeid Doaei, Naser Kalantari, Nastaran Keshavarz Mohammadi, Pantea Izadi, Maryam Gholamalizadeh, Hassan Eini-Zinab, Tuire Salonurmi, Alireza Mosavi Jarrahi, Shahram Rafieifar, Reza Janipoor, Mahnaz Sadeghypor, Ghasem Azizi Tabesh, Mark O. Goodarzi
Arch Med Sci 2019;15(5):1133–1137
CLINICAL RESEARCH
Expression of miRNAs-122, -192 and -499 in end stage renal disease associated with acute myocardial infarction
Lobna Abdelsalam, Alshaymaa A. Ibrahim, Aliaa Shalaby, Noha Osman, Assem Hashad, Dina Badawy, Hany Elghobary, Eman Amer
Arch Med Sci 2019;15(5):1247–1253
LETTER TO THE EDITOR
Association of polymorphisms of the TNFRSF11B and TNFSF11 genes with bone mineral density in postmenopausal women from western Mexico
Anahi González-Mercado, Josefina Y. Sánchez-López, Francisco J. Perea-Díaz, Maria T. Magaña-Torres, Mario Salazar-Páramo, Laura González-López, Mirna Gisel González-Mercado, Bertha Ibarra-Cortés
Arch Med Sci 2019;15(5):1352–1356
CLINICAL RESEARCH
Integrated analysis of lncRNA, miRNA and mRNA expression profiling in patients with systemic lupus erythematosus
Qin Zhang, Yan Liang, Hui Yuan, Si Li, Jie-Bing Wang, Xiao-Mei Li, Jin-Hui Tao, Hai-Feng Pan, Dong-Qing Ye
Arch Med Sci 2019;15(4):872–879
STATE OF THE ART PAPER
Hearing regeneration and regenerative medicine: present and future approaches
Arch Med Sci 2019;15(4):957–967
BASIC RESEARCH
MiR-509-5p improves the proliferative and invasive abilities of papillary thyroid carcinoma cells by inhibiting SFRP1
Arch Med Sci 2019;15(4):968–978
BASIC RESEARCH
Methylwogonin exerts anticancer effects in A375 human malignant melanoma cells through apoptosis induction, DNA damage, cell invasion inhibition and downregulation of the mTOR/PI3K/Akt signalling pathway
Arch Med Sci 2019;15(4):1056–1064
BASIC RESEARCH
Oridonin inhibits metastasis of human ovarian cancer cells by suppressing the mTOR pathway
Arch Med Sci 2019;15(4):1017–1027
BASIC RESEARCH
Differential expression study of circular RNAs in exosomes from serum and urine in patients with idiopathic membranous nephropathy
Arch Med Sci 2019;15(3):738–753
BASIC RESEARCH
Glucose fluctuation increased mesangial cell apoptosis related to AKT signal pathway
Changjiang Ying, Shanshan Wang, Yan Lu, Lei Chen, Yizhen Mao, Hongwei Ling, Xingbo Cheng, Xiaoyan Zhou
Arch Med Sci 2019;15(3):730–737
BASIC RESEARCH
Dehydrocostus lactone inhibits in vitro gastrinoma cancer cell growth through apoptosis induction, sub-G1 cell cycle arrest, DNA damage and loss of mitochondrial membrane potential
Hou-yong Long, Qing-xian Huang, Yong-yang Yu, Zhen-bin Zhang, Zeng-wu Yao, Hong-bing Chen, Jun-wei Feng
Arch Med Sci 2019;15(3):765–773
EXPERIMENTAL RESEARCH
Minocycline impedes mitochondrial-dependent cell death and stabilizes expression of hypoxia inducible factor-1α in spinal cord injury
Arch Med Sci 2019;15(2):475–483
EXPERIMENTAL RESEARCH
Neuroprotective effects of the new Na channel blocker rs100642 in global ischemic brain injury
Suat Kamisli, Cenk Basaran, Kadir Batcioglu, Mustafa Namık Oztanir, Mehmet Gul, Basri Satilmis, Ayse Burcin Uyumlu, Basak Kayhan, Metin Genc
Arch Med Sci 2019;15(2):467–474
CLINICAL RESEARCH
Age at onset of obesity, transcription factor 7-like 2 (TCF7L2) rs7903146 polymorphism, adiponectin levels and the risk of type 2 diabetes in obese patients
Arch Med Sci 2019;15(2):321–329
BASIC RESEARCH
Renin-angiotensin system inhibitor attenuates oxidative stress induced human coronary artery endothelial cell dysfunction via the PI3K/AKT/mTOR pathway
Arch Med Sci 2019;15(1):152–164
BASIC RESEARCH
Trichostatin A activates FOXO1 and induces autophagy in osteosarcoma
Yunjuan Bai, Yun Chen, Xiaochen Chen, Jiukun Jiang, Xiao Wang, Liping Wang, Jigang Wang, Jianbin Zhang, Liang Gao
Arch Med Sci 2019;15(1):204–213
EXPERIMENTAL RESEARCH
In vivo administration of quercetin ameliorates sperm oxidative stress, inflammation, preserves sperm morphology and functions in streptozotocin-nicotinamide induced adult male diabetic rats
Arch Med Sci 2019;15(1):240–249
BASIC RESEARCH
Antiproliferative and apoptotic activity of glycyrrhizinic acid in MCF-7 human breast cancer cells and evaluation of its effect on cell cycle, cell migration and m-TOR/PI3K/Akt signalling pathway
Arch Med Sci 2019;15(1):174–182
CLINICAL RESEARCH
Association of common polymorphisms in the VEGFA and SIRT1 genes with type 2 diabetes-related traits in Mexicans
Armando Totomoch-Serra, Maria de Lourdes Muñoz, Juan Burgueño, Maria Cristina Revilla-Monsalve, Alvaro Diaz-Badillo
Arch Med Sci 2018;14(6):1361–1373
BASIC RESEARCH
PAQR3 inhibits proliferation via suppressing PI3K/AKT signaling pathway in non-small cell lung cancer
Arch Med Sci 2018;14(6):1289–1297
EXPERIMENTAL RESEARCH
Connexin 43 expression in the testes during postnatal development of finasteride-treated male rat offspring
Agnieszka Kolasa-Wołosiuk, Kamila Misiakiewicz-Has, Irena Baranowska-Bosiacka, Izabela Gutowska, Maciej Tarnowski, Marta Tkacz, Barbara Wiszniewska
Arch Med Sci 2018;14(6):1471–1479
BASIC RESEARCH
MicroRNA-590-5p represses proliferation of human fetal airway smooth muscle cells by targeting signal transducer and activator of transcription 3
Arch Med Sci 2018;14(5):1093–1100
BASIC RESEARCH
Analysis of differentially expressed microRNA of TNF-α-stimulated mesenchymal stem cells and exosomes from their culture supernatant
Arch Med Sci 2018;14(5):1102–1111
SYSTEMATIC REVIEW/META-ANALYSIS
Probiotics for management of infantile colic: a systematic review of randomized controlled trials
Arch Med Sci 2018;14(5):1137–1143
CLINICAL RESEARCH
Diagnostic investigation of breast magnetic resonance imaging in malignant and benign mass lesions
Arch Med Sci 2018;14(5):1061–1069
CLINICAL RESEARCH
Association of extrapituitary prolactin promoter polymorphism with disease susceptibility and anti-RNP antibodies in Mexican patients with systemic lupus erythematosus
Jorge Hernández-Bello, Claudia A. Palafox-Sanchez, Samuel García-Arellano, Zyanya Reyes-Castillo, Ana L. Pereira-Suárez, Isela Parra-Rojas, José E. Navarro-Zarza, Ulises De la cruz-Mosso, Nora M. Torres-Carrillo, José Francisco Muñoz-Valle
Arch Med Sci 2018;14(5):1025–1032
BASIC RESEARCH
miR-181b inhibits chemoresistance in cisplatin-resistant H446 small cell lung cancer cells by targeting Bcl-2
Arch Med Sci 2018;14(4):745–751
STATE OF THE ART PAPER
2D and 3D cell cultures – a comparison of different types of cancer cell cultures
Marta Kapałczyńska, Tomasz Kolenda, Weronika Przybyła, Maria Zajączkowska, Anna Teresiak, Violetta Filas, Matthew Ibbs, Renata Bliźniak, Łukasz Łuczewski, Katarzyna Lamperska
Arch Med Sci 2018;14(4):910–919
EXPERIMENTAL RESEARCH
Pretreatment with obestatin inhibits the development of acetic acid-induced colitis in rats
Aleksandra Matuszyk, Piotr Ceranowicz, Zygmunt Warzecha, Jakub Cieszkowski, Krystyna Gałązka, Joanna Bonior, Jolanta Jaworek, Peter Christopher Konturek, Krzysztof Gil, Artur Dembiński
Arch Med Sci 2018;14(4):920–929
BASIC RESEARCH
MicroRNA-141 inhibits proliferation of gastric cardia adenocarcinoma by targeting MACC1
Arch Med Sci 2018;14(3):588–596
BASIC RESEARCH
Lutein prevents osteoarthritis through Nrf2 activation and downregulation of inflammation
Arch Med Sci 2018;14(3):617–624
BASIC RESEARCH
KLF1 gene and borderline hemoglobin A2 in Saudi population
J. Francis Borgio, Sayed AbdulAzeez, Ahmed M. Al-Muslami, Zaki A. Naserullah, Sana Al-Jarrash, Ahmed M. Al-Suliman, Mohammed S. Al-Madan, Amein K. Al-Ali
Arch Med Sci 2018;14(1):230–236
BASIC RESEARCH
Differential action of polyunsaturated fatty acids and eicosanoids on bleomycin-induced cytotoxicity to neuroblastoma cells and lymphocytes
Arch Med Sci 2018;14(1):207–229
CLINICAL RESEARCH
GABRG2 C588T gene polymorphisms might be a predictive genetic marker of febrile seizures and generalized recurrent seizures: a case-control study in a Romanian pediatric population
Anamaria Todoran Butilă, Ancuta Zazgyva, Anca Ileana Sin, Elisabeta Racoș Szabo, Mariana Cornelia Tilinca
Arch Med Sci 2018;14(1):157–166
CLINICAL RESEARCH
MGMT promoter methylation as a potential prognostic marker for acute leukemia
Dominika Sobieszkoda, Joanna Czech, Natalia Gablo, Marta Kopanska, Jacek Tabarkiewicz, Agnieszka Kolacinska, Tadeusz Robak, Izabela Zawlik
Arch Med Sci 2017;13(6):1433–1441
BASIC RESEARCH
Up-regulation of the long non-coding RNA RMRP contributes to glioma progression and promotes glioma cell proliferation and invasion
Arch Med Sci 2017;13(6):1315–1321
BASIC RESEARCH
Value of CNRIP1 promoter methylation in colorectal cancer screening and prognosis assessment and its influence on the activity of cancer cells
Ting Zhang, Ge Cui, Yun-Liang Yao, Qi-Chun Wang, Hong-Guang Gu, Xi-Ning Li, Hui Zhang, Wen-Ming Feng, Qi-Lin Shi, Weiwei Cui
Arch Med Sci 2017;13(6):1281–1294
BASIC RESEARCH
Down-regulation of microRNA-182 and microRNA-183 predicts progression of osteosarcoma
Mohammad Reza Golbakhsh, Bahram Boddouhi, Negin Hatami, Peyman Karimi Goudarzi, Mohammadreza Shakeri, Emad Yahaghi, Afshin Taheriazam
Arch Med Sci 2017;13(6):1352–1356
BASIC RESEARCH
Prognostic implications of phosphatidylinositol 3-kinase/AKT signaling pathway activation in gastric carcinomas
Paula Blandina Ola Chiappini, Ivan Ucella Dantas de Medeiros, Luiz Guilherme Cenaglia Lima, Jose Humberto Fregnani, Suely Nonogaki, Wilson Luiz da Costa Jr, Felipe Jose Fernandez Coimbra, Milton Jose de Barros e Silva, Celso Abdon Lopes de Mello, Clovis Antonio Lopes Pinto, Maria Dirlei Begnami
Arch Med Sci 2017;13(6):1262–1268