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Topic Clinical pharmacology
Editor's Choice
GUIDELINES/RECOMMENDATIONS
Position Paper of the Polish Expert Group on the Use of Pitavastatin in the Treatment of Lipid Disorders in Poland Endorsed by the Polish Lipid Association.
Maciej Banach, Stanisław Surma, Agnieszka Kapłon-Cieślicka, Przemysław Mitkowski, Grzegorz Dzida, Tomasz Tomasik, Agnieszka Mastalerz-Migas
Arch Med Sci 2024;20(1)
Editor's Choice
STATE OF THE ART PAPER
2023: The year in cardiovascular disease – the year of new and prospective lipid lowering therapies. Can we render dyslipidemia a rare disease by 2024?
Arch Med Sci 2023;19(6):1602–1615
STATE OF THE ART PAPER
Cardiac microRNAs: diagnostic and therapeutic potential
Anna Kabłak-Ziembicka, Rafał Badacz, Michał Okarski, Magdalena Wawak, Tadeusz Przewłocki, Jakub Podolec
Arch Med Sci 2023;19(5):1360–1381
RESEARCH LETTER
The effect of intravenous trehalose administration in a patient with multiple sulfatase deficiency
Shabnam Radbakhsh, Moein Mobini, Eric Gumpricht, Maciej Banach, Tannaz Jamialahmadi, Amirhossein Sahebkar
Arch Med Sci 2023;19(5):1564–1568
STATE OF THE ART PAPER
The effects of statins on the function and differentiation of blood cells
Sajjad Chamani, Omid Kooshkaki, Maryam Moossavi, Mandana Rastegar, Sara Saffar Soflaei, Alice P. McCloskey, Maciej Banach, Amirhossein Sahebkar
Arch Med Sci 2023;19(5):1314–1326
EXPERIMENTAL RESEARCH
Alternate-day fat diet and exenatide modulate the brain leptin JAK2/STAT3/SOCS3 pathway in a fat diet-induced obesity and insulin resistance mouse model
Arch Med Sci 2023;19(5):1508–1519
STATE OF THE ART PAPER
Nanoparticles: a breakthrough in COVID-19 prevention, diagnosis and treatment
Aleksandra Skwarek, Aleksandra Gąsecka, Miłosz J. Jaguszewski, Łukasz Szarpak, Tomasz Dzieciątkowski, Krzysztof J. Filipiak
Arch Med Sci 2023;19(5):1410–1420
BASIC RESEARCH
Alpinetin: anti-human gastric cancer potential and urease inhibition activity in vitro
Arch Med Sci 2023;19(5):1479–1486
CLINICAL RESEARCH
Natural and natural-like polyphenol compounds: in vitro antioxidant activity and potential for therapeutic application
Jasmina Brboric, Aleksandra Klisic, Jelena Kotur-Stevuljevic, Giovanna Delogu, Darinka Gjorgieva Ackova, Kristina Kostic, Maria Antonietta Dettori, Davide Fabbri, Paola Carta, Luciano Saso
Arch Med Sci 2023;19(3):651–671
Editor's Choice
SYSTEMATIC REVIEW/META-ANALYSIS
Clinical efficacy and safety of rituximab with membranous nephropathy: a meta-analysis
Arch Med Sci 2023;19(2):411–419
Editor's Choice
EXPERIMENTAL RESEARCH
The effect of PCSK9 immunization on the hepatic level of microRNAs associated with PCSK9/LDLR pathway.
Arch Med Sci 2023;19(1):203–208
EXPERIMENTAL RESEARCH
The effects of botulinum toxin A and papaverine on human saphenous vein and internal mammary artery grafts: an in vitro study
Arch Med Sci 2022;18(6):1607–1616
EXPERIMENTAL RESEARCH
Protective effect of vitamin D on imidacloprid-induced testicular injury in rats
Arch Med Sci 2022;18(6):1659–1665
SYSTEMATIC REVIEW/META-ANALYSIS
Effect of N-acetyl-cysteine in prevention of noise-induced hearing loss: a systematic review and meta-analysis of randomized controlled trials
Arch Med Sci 2022;18(6):1535–1541
RESEARCH LETTER
Comparison of antibiotic use in the COVID-19 pandemic with the pre-pandemic period in a university hospital
Arch Med Sci 2022;18(5):1392–1394
SYSTEMATIC REVIEW/META-ANALYSIS
Efficacy of early treatment with hydroxychloroquine in people with mild to moderate COVID-19: a systematic review and meta-analysis
Adrian V. Hernandez, John Ingemi III, Michael Sherman, Vinay Pasupuleti, Joshuan J. Barboza, Alejandro Piscoya, Yuani M. Roman, C. Michael White
Arch Med Sci 2022;18(4):939–948
SYSTEMATIC REVIEW/META-ANALYSIS
Effects of acetaminophen and ibuprofen monotherapy in febrile children: a meta-analysis of randomized controlled trials
Arch Med Sci 2022;18(4):965–981
STATE OF THE ART PAPER
Influence of lipid-lowering drugs on inflammation: what is yet to be done?
Arch Med Sci 2022;18(4):855–869
LETTER TO THE EDITOR
Eosinophilia in a patient with ankylosing spondylitis treated with prolonged adalimumab only
Arch Med Sci 2022;18(2):564–567
RESEARCH LETTER
Comparison of rituximab, cyclophosphamide, and tacrolimus as first steroid-sparing agents for complicated relapsing/steroid-dependent nephrotic syndrome in children: an evaluation of the health-related quality of life
Arch Med Sci 2022;18(1):275–278
BASIC RESEARCH
Genetic polymorphism of CYP3A4 is associated with poor response to ifosfamide treatment in children with solid embryonic tumors
Luz María Torres Espindola, Manuel De JesÚs Castillejos López, Armando De Uña Flores, Liliana Rivera Espinosa, Julio Granados, Juan Luis Chávez Pacheco, Martín Pérez García, Ma Teresa Ramos Cervantes, Vilma Carolina Bekker Méndez, Susana Hernández Doño, Daniela Ruíz Gómez
Arch Med Sci 2021;17(6):1766–1771
BASIC RESEARCH
Downregulation of long non-coding RNA B-Raf proto-oncogene-activated non-coding RNA reverses cisplatin resistance in laryngeal squamous cell carcinoma
Arch Med Sci 2021;17(5):1164–1174
BASIC RESEARCH
NGS study of glucocorticoids response genes in inflammatory bowel disease patients
Marzena Skrzypczak-Zielinska, Marcin Gabryel, Daria Marszalek, Agnieszka Dobrowolska, Ryszard Slomski
Arch Med Sci 2021;17(2):417–433
EXPERIMENTAL RESEARCH
Effects of melatonin on ovarian reserve in cigarette smoking: an experimental study
Emre Kole, Sebiha Ozdemir Ozkan, Ceyla Eraldemir, Furuzan Yildiz Akar, Sema Kurnaz Ozbek, Merve Cakir Kole, Tugba Kum, Pelin Costur Filiz
Arch Med Sci 2020;16(6):1376–1386
RESEARCH LETTER
Modulation of pro-inflammatory and pro-resolution mediators by γ-linolenic acid: an important element in radioprotection against ionizing radiation
Arch Med Sci 2020;16(6):1448–1456
LETTER TO THE EDITOR
Antioxidant therapy in the management of Fluoroquinolone - Associated Disability
Arch Med Sci 2020;16(6):1483–1486
CLINICAL RESEARCH
The incidence of recurrent cardiovascular events among acute coronary syndrome patients treated with generic or original clopidogrel in relation to their sociodemographic and clinical characteristics. The Aegean study
Nikolaos G. Patsourakos, Matina Kouvari, Apostolos Kotidis, Kallirroi I. Kalantzi, Maria E. Tsoumani, Filippos Anastasiadis, Panagiotis Andronikos, Theano Aslanidou, Petros Efraimidis, Anastasios Georgiopoulos, Kalliopi Gerakiou, Eleni Grigoriadou-Skouta, Panagiotis Grigoropoulos, Dionysios Hatzopoulos, Athanasios Kartalis, Anastasios Lyras, Gerasimos Markatos, Aristeidis Mikrogeorgiou, Ioannis Myroforou, Anestis Orkopoulos, Pavlos Pavlidis, Charalampos Petras, Maria Riga, Marina Skouloudi, Nikolaos Smyrnioudis, Konstantinos Thomaidis, Grammatiki E. Tsikouri, Emmanuel I. Tsikouris, Konstantinos Zisimos, Panagiotis Vavoulis, Maria-Gabriella Vitali, George Vitsas, Constantinos Vogiatzidis, Stylianos Chantanis, Stefanos Fousas, Demosthenes B. Panagiotakos, Alexandros D. Tselepis
Arch Med Sci 2020;16(5):1013–1021
SYSTEMATIC REVIEW/META-ANALYSIS
Effects of antidepressants on QT interval in people with mental disorders
Arch Med Sci 2020;16(4):727–741
EXPERIMENTAL RESEARCH
Effect of β-asarone in normal and β-amyloid-induced Alzheimeric rats
Arch Med Sci 2020;16(3):699–706
CLINICAL RESEARCH
RIVAroxaban TWICE daily for lysis of thrombus in the left atrial appendage in patients with non-valvular atrial fibrillation: the RIVA-TWICE study
Roman Piotrowski, Beata Zaborska, Ewa Pilichowska-Paszkiet, Małgorzata Sikora-Frąc, Jakub Baran, Piotr Kułakowski
Arch Med Sci 2020;16(2):289–296
BASIC RESEARCH
Lysyl hydroxylase 3 increases collagen deposition and promotes pulmonary fibrosis by activating TGFβ1/Smad3 and Wnt/β-catenin pathways
Songjun Shao, Haiyan Fang, Lindi Duan, Xianwei Ye, Shanshan Rao, Jin Han, Yumei Li, Guohang Yuan, Weijia Liu, Xiangyan Zhang
Arch Med Sci 2020;16(2):436–445
COMMENTARY
The role of curcumin in liver diseases
Antonio Riccardo Buonomo, Riccardo Scotto, Salvatore Nappa, Michele Arcopinto, Andrea Salzano, Alberto Maria Marra, Roberta D’Assante, Emanuela Zappulo, Guglielmo Borgia, Ivan Gentile
Arch Med Sci 2019;15(6):1608–1620
CLINICAL RESEARCH
Topical morphine for treatment of cancer-related painful mucosal and cutaneous lesions: a double-blind, placebo-controlled cross-over clinical trial
Arch Med Sci 2019;15(1):146–151
SYSTEMATIC REVIEW/META-ANALYSIS
A systematic review and meta-analysis of clinical trials investigating the effects of flaxseed supplementation on plasma C-reactive protein concentrations
Sorin Ursoniu, Amirhossein Sahebkar, Maria-Corina Serban, Iulia Pinzaru, Cristina Dehelean, Lavinia Noveanu, Jacek Rysz, Maciej Banach, Lipid and Blood Pressure Meta-analysis Collaboration (LBPMC) Group
Arch Med Sci 2019;15(1):12–22
BASIC RESEARCH
Evaluation of the effects of pregabalin on chondrocyte proliferation and CHAD, HIF-1α, and COL2A1 gene expression
Arch Med Sci 2018;14(6):1340–1347
BASIC RESEARCH
Plumbagin protects against hydrogen peroxide-induced neurotoxicity by modulating NF-κB and Nrf-2
Arch Med Sci 2018;14(5):1112–1118
BASIC RESEARCH
miR-181b inhibits chemoresistance in cisplatin-resistant H446 small cell lung cancer cells by targeting Bcl-2
Arch Med Sci 2018;14(4):745–751
BASIC RESEARCH
Lutein prevents osteoarthritis through Nrf2 activation and downregulation of inflammation
Arch Med Sci 2018;14(3):617–624
EXPERIMENTAL RESEARCH
Indomethacin-induced gastric damage in rats and the protective effect of donkey milk
Arch Med Sci 2018;14(3):671–678
LETTER TO THE EDITOR
Methotrexate-induced pancytopenia in a patient with ectopic pregnancy
Arch Med Sci 2018;14(2):475–476
BASIC RESEARCH
Differential action of polyunsaturated fatty acids and eicosanoids on bleomycin-induced cytotoxicity to neuroblastoma cells and lymphocytes
Arch Med Sci 2018;14(1):207–229
CLINICAL RESEARCH
The influence of various therapeutic regimens on early clinical and laboratory response and outcome of children with secondary hemophagocytic lymphohistiocytosis
Arch Med Sci 2018;14(1):138–150
CLINICAL RESEARCH
Preoperative immunonutrition regulates tumor infiltrative lymphocytes and increases tumor angiogenesis in gastric cancer patients
Kivanc Derya Peker, Sidika Seyma Ozkanli, Cebrail Akyuz, Orhan Uzun, Necdet Fatih Yasar, Mustafa Duman, Sinan Yol
Arch Med Sci 2017;13(6):1365–1372
CLINICAL RESEARCH
Moderate-dose atorvastatin improves arterial endothelial function in patients with angina pectoris and normal coronary angiogram: a pilot study
Arch Med Sci 2017;13(4):827–836
CLINICAL RESEARCH
The effect of orlistat versus metformin on body composition and insulin resistance in obese premenopausal women: 3-month randomized prospective open-label study
Magdalena Kujawska-Łuczak, Katarzyna Musialik, Monika Szulińska, Ewelina Swora-Cwynar, Angelina Kargulewicz, Małgorzata Grzymisławska, Danuta Pupek-Musialik, Paweł Bogdański
Arch Med Sci 2017;13(4):725–731
CLINICAL RESEARCH
The relationship between pharmacokinetic parameters of carbamazepine and therapeutic response in epileptic patients
Chahra Chbili, Anis Hassine, Aicha Laouani, Sana Ben Amor, Manel Nouira, Sofiène Ben Ammou, Saad Saguem
Arch Med Sci 2017;13(2):353–360
STATE OF THE ART PAPER
New agents approved for treatment of acute staphylococcal skin infections
Arch Med Sci 2016;12(6):1327–1336
STATE OF THE ART PAPER
Cardiotoxicity of anthracycline therapy: current perspectives
Arch Med Sci 2016;12(2):428–435
EXPERIMENTAL RESEARCH
Exendin-4 enhances expression of Neurod1 and Glut2 in insulin-producing cells derived from mouse embryonic stem cells
Arch Med Sci 2016;12(1):199–207
Letter to the Editor
Telmisartan/hydrochlorothiazide-induced hepatotoxicity
Marco Lorena, Aldo Autolitano, Giovanni Natale, Federica Uberti, Fabrizio Vitali, Camillo Schiantarelli, Nicola Lucio Liberato
Arch Med Sci 2015;11(4):893–894
Commentary
Can Halberg’s approach to chronotherapy improve world health?
Arch Med Sci 2015;11(4):911–913
State of the art paper
Potential role of dietary lipids in the prophylaxis of some clinical conditions
Arch Med Sci 2015;11(4):807–818
Letter to the Editor
Biological drugs for inducing remission in patients with Crohn’s disease: determining statistical equivalence according to evidence-based methods
Arch Med Sci 2015;11(2):458–460
State of the art paper
Improvement of hepatic bioavailability as a new step for the future of statin
Arch Med Sci 2015;11(2):406–410
Basic research
Efficacy of low dose temozolomide in combination with bortezomib in U87 glioma cells: a flow cytometric analysis
Arch Med Sci 2015;11(2):307–310
Letter to the Editor
Possible association between fluconazole administration and acute hyperkalemia in a critically ill cyanotic infant
Arch Med Sci 2015;11(1):235–236
Experimental research
Mechanism of endothelial cyto-protective and thrombo-resistance effects of sildenafil, vardenafil and tadalafil in male rabbit
Arch Med Sci 2015;11(1):190–198
Clinical research
Searching for factors associated with resistance to acetylsalicylic acid used for secondary prevention of stroke
Beata Łabuz-Roszak, Krystyna Pierzchała, Ewa Niewiadomska, Michał Skrzypek, Agnieszka Machowska-Majchrzak
Arch Med Sci 2015;11(1):106–114
State of the art paper
Tumor necrosis factor inhibitors – state of knowledge
Arch Med Sci 2014;10(6):1175–1185
State of the art paper
Aliskiren – an alternative to angiotensin-converting enzyme inhibitors or angiotensin receptor blockers in the therapy of arterial hypertension
Arch Med Sci 2014;10(4):830–836
Experimental research
Comparing the effects of inorganic nitrate and allopurinol in renovascular complications of metabolic syndrome in rats: role of nitric oxide and uric acid
Arch Med Sci 2014;10(3):537–545
Clinical research
Hyperkalemia among hospitalized patients and association between duration of hyperkalemia and outcomes
Jagadish Khanagavi, Tanush Gupta, Wilbert S. Aronow, Tushar Shah, Jalaj Garg, Chul Ahn, Sachin Sule, Stephen Peterson
Arch Med Sci 2014;10(2):251–257
Clinical research
Naloxone therapy in opioid overdose patients: intranasal or intravenous? A randomized clinical trial
Arch Med Sci 2014;10(2):309–314
Clinical research
Exhaled eicosanoids and biomarkers of oxidative stress in exacerbation of chronic obstructive pulmonary disease
Adam Antczak, Maciej Ciebiada, Tadeusz Pietras, Wojciech J. Piotrowski, Zofia Kurmanowska, Paweł Górski
Arch Med Sci 2012;8(2):277–285
Editorial
The clinical benefit of implementing guidelines in cardiovascular disease prevention in real world settings
Arch Med Sci 2012;8(1):6–10
Basic research
The effects of palm vitamin E on stress hormone levels and gastric lesions in stress-induced rats
Arch Med Sci 2012;8(1):22–29
Clinical research
Pharmacokinetics of mycophenolic acid and its phenyl glucuronide metabolite in kidney transplant recipients with renal impairment
Arch Med Sci 2012;8(1):88–96
Clinical research
Hypotensive effect of atorvastatin in hypertensive patients: the association among flow-mediated dilation, oxidative stress and endothelial dysfunction
Agnieszka M. Tycinska, Jacek Janica, Barbara Mroczko, Wlodzimierz J. Musial, Robert Sawicki, Bozena Sobkowicz, Karol Kaminski, Urszula Lebkowska, Maciej Szmitkowski
Arch Med Sci 2011;7(6):955–962
Case report
Persistent ductus arteriosus in a 72-year-old woman with paroxysmal atrial fibrillation and depression syndrome: a therapeutic and diagnostic problem
Adam Rafał Poliwczak, Marzena Koziróg, Justyna Zabielska, Agnieszka Bała, Piotr Lipiec, Marlena Broncel
Arch Med Sci 2011;7(5):914–917
Clinical research
Safety and impact on cardiovascular events of long-term multifactorial treatment in patients with metabolic syndrome and abnormal liver function tests: a post hoc analysis of the randomised ATTEMPT study
Vassilios G. Athyros, Olga Giouleme, Emmanouel S. Ganotakis, Moses Elisaf, Konstantinos Tziomalos, Themistoklis Vassiliadis, Evangelos N. Liberopoulos, Eleni Theocharidou, Asterios Karagiannis, Dimitri P. Mikhailidis
Arch Med Sci 2011;7(5):796–805
Clinical research
Comparative study of fentanyl and morphine in addition to hyperbaric or isobaric bupivacaine in combined spinal anaesthesia for caesarean section
Arch Med Sci 2011;7(4):694–699
Basic research
Carboxylic acid derivatives of histone deacetylase inhibitors induce full length SMN2 transcripts: a promising target for spinal muscular atrophy therapeutics
Arch Med Sci 2011;7(2):230–234
CLINICAL RESEARCH
The effect of trehalose administration on the serum expression levels of microRNAs associated with lipid metabolism and the autophagy process in patients with myocardial infarction – post-hoc analysis of the IR-TREAT trial
Shiva Ganjali, Atena Mansouri, Željko Reiner, Tannaz Jamialahmadi, Seyed Adel Moallem, Sepideh Salehabadi, Maciej Banach, Amirhossein Sahebkar
SYSTEMATIC REVIEW/META-ANALYSIS
Efficacy and safety of tigecycline doses for ventilator-associated pneumonia caused by multiple resistant bacteria: a systematic review and meta-analysis
Editor's Choice
RESEARCH PAPER
Trehalose-induced alterations in serum expression levels of microRNAs associated with vascular inflammation in patients with coronary artery disease - the pilot results from the randomized controlled trial.
Shiva Ganjali, Tannaz Jamialahmadi, Mitra Abbasifard, Seyed Ahmad Emami, Zahra Tayarani-Najaran, Alexandra E. Butler, Maciej Banach, Amirhossein Sahebkar
STATE OF THE ART PAPER
An update on the incidence, risk factors and mechanisms of rituximab-associated neutropenia
RESEARCH PAPER
Does prior SARS-CoV-2 infection increase the risk of adverse effects after mRNA vaccination (BNT162b2) - the retrospective cohort study of physicians.
Marcin Hachuła, Michal Kosowski, Eliza Wojciechowska, Mateusz Maliglowka, Marcin Basiak, Boguslaw Okopien
RESEARCH PAPER
Acetyl-L-carnitine protects against LPS induced depression via PPAR-γ induced inhibition of NF-κB/NLRP3 pathway
Amna Samin, Lina Tariq Al Kury, Shabir Hussain, Muhammad Imran Khan, Abdullah Alattar, Reem Alshaman, Fawad Ali Shah, Muhammad Aamir, Shupeng Li
SYSTEMATIC REVIEW/META-ANALYSIS
Safety of denosumab versus zoledronic acid in patients with bone-related diseases: a systematic review and meta-analysis
CLINICAL RESEARCH
Association between cluster of differentiation 24 (CD24) polymorphism, talin-1 gene expression and hepatocellular carcinoma prevalence in the Egyptian population
RESEARCH PAPER
Inhibition of histone deacetylase promotes a neuroprotective mechanism in an experimental model of Parkinson’s disease
Arch Med Sci 2024;20(2)
EXPERIMENTAL RESEARCH
Oleuropein modulates over-proliferation of keratinocytes in mice with imiquimodmediated psoriasis and inhibits differentiation of TH17 cells through the JAK3/STAT3 axis
SYSTEMATIC REVIEW/META-ANALYSIS
Comparative tolerability of targeted therapies in pulmonary hypertension
Arch Med Sci 2024;20(1)
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