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Editor's Choice
STATE OF THE ART PAPER
Atherosclerosis features in patients with heart failure
Alexandr Ceasovschih, Nikolina Banjanin, Anna Bednarek, Aldo Beqiraj, Maria Cherska, Malik Ejubović, Marta Jakubova, Sura Markos, Vladimir Ristovski, Roberto Scicali, Maciej Banach, Victorita Sorodoc, Antonio M. Gotto
RESEARCH PAPER
Epidemiological trends and burden of osteoarthritis in United States: Insights from the GBD 2021 study
RESEARCH PAPER
Bidirectional Associations of Depression, Anxiety, Sleep Disorders, and Constipation: Insights from Mendelian Randomization
Qi Zheng, Yingjian Deng, Yajuan Ji, Chunmei Shao, Qi Liu, Chenyun Zhang, Tiantian Zhang, Xinchao Chen
RESEARCH PAPER
Mendelian randomization identifies the characteristic plasma metabolite profile of meningioma
RESEARCH PAPER
Evaluating Causal Relationship between Sex Hormones and Oral Cavity Cancer: Mendelian Randomization Study
STATE OF THE ART PAPER
Definition of maximum daily amounts of vitamins and minerals allowed in food supplements: scientific rationale and European regulatory frameworks
RESEARCH PAPER
A Multi-Stage Genomic Approach to Uncover Druggable Gene Targets and Neural Pathways in Postpartum Depression
RESEARCH PAPER
Changes in plasma concentration of cell-free DNA as a response to physical activity
Jaroslav Alois Hubacek, Dana Dlouhá, Hana Wünsch, Kryštof Slabý, Sabína Oreská, Aneta Prokopcová, Marian Rybář, Michal Vrablík, Michal Tomčík
RESEARCH PAPER
Comprehensive Expression of Long non-coding RNAs and association with the Iron and Erythropoiesis Regulatory Proteins in Transfusion-dependent β-Thalassemia
Ola M. Al-Sanabra, Wafa' J. Haza, Abeer A. Haza'a, Diya Hasan, Mutaz Jamal Al-Khreisat, Majd M. Alsaleh, Ahmed M. Al Tibi
CLINICAL RESEARCH
miRNA-mediated regulation of extracellular matrix dynamics across breast cancer subtypes
Tomasz Sirek, Przemysław Borawski, Katarzyna Król-Jatręga, Agata Sirek, Nikola Zmarzły, Dariusz Boroń, Michał Chalcarz, Piotr Ossowski, Konrad Dziobek, Damian Strojny, Joanna Sułkowska, Julia Gajdeczka, Elżbieta Mitka-Krysiak, Grzegorz Wyrobiec, Kacper Boroń, Beniamin Oskar Grabarek
RESEARCH PAPER
Impact of HKDC1 Genetic Variants on Gestational Diabetes and Hypothyroidism in Pregnancy - A Pilot Study
RESEARCH PAPER
Correlation of Age-adjusted Visceral Adiposity Index with Osteoarthritis Risk: A Cross-sectional Study from NHANES 1999–2018
RESEARCH PAPER
Predictive factors of improved postoperative results after surgery for patients with hepatocellular carcinoma: A retrospective study
RESEARCH PAPER
Development of tRNA-based biomarkers for breast cancer: Insight from machine learning
RESEARCH PAPER
Effect of IL-6, IL-8, and IL-17A on Predicting Treatment Outcomes in PD-1 Blockade Immunochemotherapy in Advanced Gastric Cancer
RESEARCH PAPER
Exploring causal correlations between inflammatory response related genes and Osteoporosis: A Multi-Omics Mendelian Randomization Study
RESEARCH PAPER
Genetic causal relationship between physical activity and osteoarthritis: a two-sample Mendelian randomization study
Mingyi Yang, Hui Yu, Yani Su, Pengfei Wen, Jiale Xie, Xianjie Wan, Ke Xu, Lin Liu, Zhi Yang, Peng Xu
RESEARCH PAPER
Exploring causality between peripheral blood B cell subtypes and membranous nephropathy: A two-sample Mendelian randomization study
RESEARCH PAPER
Early treatment with ofatumumab increases the likelihood of stabilizing disease in patients with relapsing-remitting multiple sclerosis.
Adam Stepień, Aleksandra Pogoda-Wesołowska, Jacek Staszewski, Waldemar Brola, Karolina Kania, Ewa Krzystanek, Stanisław Rusek, Radosław Zajdel, Marek Hałas, Bartosz Karaszewski
RESEARCH PAPER
M1 Macrophage Exosomes Induce Ferroptosis via MiR-582-5p-Mediated ZBTB10 Suppression in Sepsis-Induced Acute Kidney Injury
CLINICAL RESEARCH
The role of body mass index and tumor necrosis factor α in breast cancer development: a case-control study
RESEARCH PAPER
Associations of preoperative Oswestry Disability Index and EuroQol-5D with long-term all-cause mortality in patients undergoing percutaneous vertebroplasty
Yu-Hsien Lin, Yun-Che Wu, Yu-Tsung Lin, Wen-Chien Wang, Kun-Hui Chen, Chien-Chou Pan, Ching-Heng Lin, Jun-Sing Wang, Cheng-Hung Lee
CLINICAL RESEARCH
Increased blood urea nitrogen to serum albumin ratio is associated with poor prognosis in patients with acute pancreatitis: a retrospective cohort study
CLINICAL RESEARCH
Causal relationship between inflammatory bowel disease and cardiovascular disease: a two-sample Mendelian randomized study
Lianghao Ma, Lishan Ding, Zuoying Xing, Hongjie Ren, Jingjing Wei, Huanhuan Song, Boyong Qiu, Zhaoqi Chen, Yongxia Wang
CLINICAL RESEARCH
Is the neutrophil/lymphocyte ratio a useful index in the differential diagnosis of malignancy and tuberculosis-related ascites?
CLINICAL RESEARCH
Genetic causal associations between serum metabolites and infertility: a Mendelian randomization study
RESEARCH PAPER
UBC9 silencing-mediated PPARα desumoylation induces inhibition of cell proliferation by ferroptosis in acute myeloid leukemia
CLINICAL RESEARCH
From expression to immune responses: exploring the multifaceted roles of CTNNBIP1 in osteosarcoma
Editor's Choice
RESEARCH PAPER
Hypertensive heart disease mortality trends attributable to high body mass index over the period 1990-2021 and projections up to 2040
Zhaohui Xu, Letai Li, Yinqin Hu, Jiahui Yang, Qiqi Wan, Xinyu Zhang, Rongjia Liu, Cheng Lu, Yongming Liu
RESEARCH PAPER
Causal relationship between 91 circulating inflammatory proteins and osteomyelitis risk: evidence from a Mendelian randomization study
RESEARCH PAPER
Assessing Hepatosteatosis in Endogenous Cushing Syndrome: The Hepatic Steatosis Index as a Reliable Diagnostic Tool
Burcak Cavnar Helvaci, Abbas Ali Tam, Beril Turan Erdogan, Sevgul Faki, Neslihan Cuhaci Seyrek, Oya Topaloglu, Reyhan Ersoy, Bekir Cakir
CLINICAL RESEARCH
APOE suppresses osteosarcoma by modulating ferroptosis through the mTOR/Stat3 signaling pathway
CLINICAL RESEARCH
A silent crisis: two decades of anaemia trends among women in the Eastern Mediterranean Region (2000–2019)
CLINICAL RESEARCH
CircRNA_103809/miR-516a/FBXL18 contributes to stemness and gemcitabine resistance of bladder cancer cells
CLINICAL RESEARCH
Association of the triglyceride glucose index with computed tomography-based low muscle mass
RESEARCH PAPER
Does Regular Physical Activity During Hemodialysis Affect the Levels of FoxO Proteins and Myostatin Concentration?
Agnieszka Turoń-Skrzypińska, Alicja Mińko, Aleksandra Rył, Katarzyna Mańkowska, Aneta Cymbaluk-Płoska, Kazimierz Ciechanowski, Iwona Rotter
EXPERIMENTAL RESEARCH
Reinforcement of osteogenic and mechanical properties of calcium phosphate cement with palm tocotrienol
Siti Sarah Md Dali, Ahmad Saqif Nazib, Nik Adlina Sofea Abd Rahim, Siti Nur Khadijah Sha'ari, Xin Qi Goh, Kok-Yong Chin, Fairus Ahmad, Sok Kuan Wong
CLINICAL RESEARCH
Effect of immune cells and plasma metabolites on osteomyelitis: a two-sample Mendelian randomization and mediation analysis
RESEARCH PAPER
Exploring the association between gut microbiota and venous thromboembolism using a Mendelian randomization analysis
RESEARCH PAPER
Interplay between parathyroid hormone concentration and valvular and aortic calcifications
Anna Olasińska-Wiśniewska, Kajetan Grodecki, Karolina Jemielity, Tomasz Urbanowicz, Marcin Misterski, Marek Grygier, Piotr Kübler, Bartłomiej Perek, Marcin Protasiewicz, Damini Dey, Marek Jemielity
RESEARCH PAPER
Exploring the Association Between Asthma and Frailty: A Cross-Sectional and A Bidirectional Mendelian Randomization study
Shufei Peng, Huanxian Liu, Xianfeng Ren, Lijuan Guo, Shuai Li, Xiaohai Xu, Meikui Wu, Yi Tian, Bing Mu, Ruihang Chai, Zhixing Guo, Xiaoyan Liu, Hui Zheng, Cheng Ni
RESEARCH PAPER
Genetically predicted 1,400 blood metabolites related to the risk of ovarian cancer: A Mendelian randomization study
CLINICAL RESEARCH
STXBP1 inhibits glioma progression by modulating ferroptosis and epithelial-mesenchymal transition
CLINICAL RESEARCH
Development and verification of a novel disulfidptosis-related lncRNA prognostic model for predicting the immune environment and treatment of breast cancer
STATE OF THE ART PAPER
Clinical applications of deep learning in distinguishing Benign from Malignant Pulmonary Nodules in CT Scans
RESEARCH PAPER
HER2-Low Status in Breast Cancer: Clinicopathological Factors and Prognostic Value.
Joanna Huszno, Zofia Kołosza, Ewa Stobiecka, Dorota Ponikiewska, Bogna Szcześniak, Jakub Simek, Ewa Chmielik
RESEARCH PAPER
The Effect of Spiritual Coping Skills on Psychological Resilience and Health Beliefs of Mothers with Children with Special Needs
RESEARCH PAPER
Risk factors of postoperative intracranial infection in individuals suffering from hypertensive intracerebral hemorrhage
CLINICAL RESEARCH
Global health implications of urticaria burden (1990–2021): a comprehensive analysis of trends across nations and regions
RESEARCH PAPER
The Plasma Metabolite-Mediated Relationship between Inflammatory Cytokines and Acute Respiratory Distress Syndrome
RESEARCH PAPER
Unraveling the Impact of Neonatal Jaundice on Allergic Diseases: A Mendelian Randomization Study
STATE OF THE ART PAPER
The Importance of TNF-α Signaling – Potential Risk Factor in Neurodegenerative and Cardiovascular Diseases
CLINICAL RESEARCH
Enhanced neuroprotection against Alzheimer’s disease by combining Inula viscosa with curcumin: an in vitro study
Ares Alizade, Gülüzar Özbolat, Seydi Ahmet Şengül, Mustafa Cellat, İbrahim Ozan Tekeli, Halil Mahir Kaplan, Menderes Yusuf Terzi
CLINICAL RESEARCH
Investigating causal relationships between coffee consumption and gynecological diseases: a Mendelian randomization study
RESEARCH PAPER
Visual impairment and frailty: insight from genetic correlation and Mendelian randomization
RESEARCH PAPER
Research based on nucleotide polymorphism reveals the role of inflammatory cytokines in regulating the influence of blood metabolites on drug-related osteonecrosis.
Yazhou Li, Jiang Peng, Yanbin Wu, Junming Zhang, Xianghui Mei, Jiazhou Wu, Zexian Liu, Tao Qian, Junli Wang, Zaodi Mi, Ying He, Xiaohan Sun, Aiyuan Wang
CLINICAL RESEARCH
ACOT1 eQTL: a gene involved in lipid metabolism that modulates erectile dysfunction progression via metabolites
BASIC RESEARCH
Bidirectional causal association between type 1 diabetes and autoimmune diseases: a Mendelian randomization study
Liang Han, Youpeng Su, Hua Huang, Jiahui Yan, Tingting Li, Xin Ba, Weiji Lin, Ruiyuan Zhang, Pan Shen, Yao Huang, Ying Huang, Kai Qin, Yu Wang, Zhe Chen, Liang Zou, Shenghao Tu
EXPERIMENTAL RESEARCH
Correlative study on the expression of adipokine CTRP9 in a rat model of right ventricular outflow tract obstruction
CLINICAL RESEARCH
An immune escape-related gene signature for predicting the prognostic and immune microenvironment in osteosarcoma
CLINICAL RESEARCH
Risk stratification of soft tissue sarcoma based on activity of prognostic molecules associated with unpolarized macrophages
CLINICAL RESEARCH
RXRA induces endoplasmic reticulum stress via ATP2A3 transcriptional modulation in ovarian cancer cells
Lina Zhao, Lidong Zeng, Shan Tan, Qin Lu, Xiaofeng Wang, Jun Jiang, Yiming Wang, Jianqiao Peng, Qi Zhang
CLINICAL RESEARCH
Identifying the causal relationship between gut microbiota and lymphoma disease: a Mendelian randomization study and meta-analysis
CLINICAL RESEARCH
Establishing reference intervals for serum glutathione reductase in healthy adults
CLINICAL RESEARCH
Clinical effects of stent implantation on lower extremity deep venous thrombosis with severe iliac vein stenosis
CLINICAL RESEARCH
Sleep disorders and renal failure: exploring the role of creatinine and sleep apnea syndrome through cross-sectional studies and Mendelian randomization analysis
RESEARCH PAPER
Exploring necroptosis-associated genes: implications for immune responses and therapeutic strategies in diabetic foot ulcers
RESEARCH PAPER
Cuproptosis-induced up-regulation of RBM24 suppresses tumor metastasis via MAPK signaling blockage in colorectal cancer
Tianchen Huang, Dongxiao Bai, Yong Zhang, Kan Li, Zhipeng Guo, Lei Li, Xiaodong Han, Yachao Wu, Yanshan Xin, Weijie Wang
RESEARCH PAPER
Machine learning for the prediction of in-ICU mortality in sepsis: an observational study using the MIMIC IV database
Sitong Liu, Lingmin Gong, Weiwei Hu, Jiaxin Cai, Yuhui Yang, Shiyu Chen, Baibing Mi, Yaling Zhao, Leilei Pei, Fangyao Chen
CLINICAL RESEARCH
A persistent burden: global prevalence of and changes in anaemia by country income in children aged 6–59 months (2000–2019)
STATE OF THE ART PAPER
Proceeding and Treatment of Breast Cancer in Pregnant Women
Katarzyna Mielniczek, Magdalena Leśniewska, Katarzyna Chawrylak, Zuzanna Pelc, Katarzyna Sędłak, Wojciech P. Polkowski, Karol Rawicz-Pruszyński
CLINICAL RESEARCH
The rare glucose response curve during oral glucose tolerance tests in pregnant Chinese women and its association with preterm birth
CLINICAL RESEARCH
Trajectories of cardiovascular risk factors during childhood as predictors of subclinical atherosclerosis in young adults
RESEARCH LETTER
Association between the IGF family members and UTUC: a Mendelian randomization study
RESEARCH PAPER
Facts and myths about use and effect of statins in patients with dyslipidaemia - a survey of physicians.
CLINICAL RESEARCH
The protective effect of sodium-glucose cotransporter 2 inhibitors and the incidence of ovarian cancer: a nationwide cohort preliminary study
CLINICAL RESEARCH
Withaferin-A inhibits colorectal cancer growth and metastasis by targeting the HSP90/HIF-1α/EMT axis
Editor's Choice
RESEARCH PAPER
Telomere length across the spectrum of metabolic health – an analysis from the LIPIDOGEN2015 study
Maciej Banach, Martyna Fronczek, Anna Goc, Mateusz Lejawa, Ewa Boniewska-Bernacka, Tadeusz Osadnik, Anna Pańczyszyn, Joanna Katarzyna Strzelczyk, Natalia Pawlas, Marek Gierlotka, Marcin Goławski, Karol Krystek, Agnieszka Gach, Kamila Osadnik, Jacek Jóźwiak
RESEARCH PAPER
Mechanistic Study of Long Non-Coding RNA SNHG3 in Promoting Prostate Cancer Proliferation and Invasion
RESEARCH PAPER
Unveiling the Immune Related ceRNA Network in Osteoarthritis: Key Biomarkers and Therapeutic Targets
Editor's Choice
RESEARCH PAPER
Sleep Disturbances and Heart Failure: Observational Study and Mendelian Randomization Study
RESEARCH PAPER
Association between immune cells and membranous nephropathy: a two-sample Mendelian randomization study
STATE OF THE ART PAPER
Cellular therapy for traumatic brain injury in adults: a meta-analysis of controlled clinical trials
Mujahid Alizada, Jinxiang Wu, Mirwais Alizada, James Reeves Mbori Ngwayi, Muhebullah Alizada, Shu Lin, Hongzhi Gao
RESEARCH PAPER
Inflammation response index (SIRI) is associated with all-cause and cardiovascular mortality in maintenance hemodialysis patients
Editor's Choice
RESEARCH PAPER
The causal effects of placental weight on atherosclerotic cardiovascular disease: a Mendelian randomization and mediation analysis
CLINICAL RESEARCH
Effective treatment for fatty liver of liraglutide via inhibiting endoplasmic reticulum stress, oxidative stress and apoptosis pathways
RESEARCH PAPER
Therapeutic Potential of Mesenchymal Stem Cells in Cisplatin-Induced Acute Kidney Injury via ASK-1/TXNIP Pathway Modulation
CLINICAL RESEARCH
High levels of uric acid upregulate endothelin receptors: the role of MAPK pathways in an in vitro study
Editor's Choice
BASIC RESEARCH
Application of Mendelian randomization to explore the genetic association between drinking habits of different beverages and sleep disorder
CLINICAL RESEARCH
Evaluation of differences between initial and recurrent acute pancreatitis in the intensive care unit
Editor's Choice
STATE OF THE ART PAPER
Implications for the role of natural products in Parkinson disease therapy
CLINICAL RESEARCH
Causal association between vitamin D levels and neonatal jaundice: results from a Mendelian randomization study
CLINICAL RESEARCH
Impact of emergency point-of-care ultrasound on time to diagnosis and treatment amongst patients with ectopic pregnancy: a systematic review and meta-analysis
BASIC RESEARCH
Comparative investigation of immune-related biomarkers related to alopecia areata subtypes
CLINICAL RESEARCH
The association between metabolic associated fatty liver disease and depression in adults: the role of physical activity levels and types
Editor's Choice
RESEARCH PAPER
Resumption versus discontinuation of direct oral anticoagulation after an episode of gastrointestinal bleeding: a systematic review and meta-analysis of rebleeding episodes
Bianca Codrina Morarasu, Laurentiu Sorodoc, Stefan Morarasu, Emilia Adriana Marciuc, Raluca Ecaterina Haliga, Alexandr Ceasovschih, Mihai Constantin, Alexandra Stoica, Alexandra Diana Diaconu, Bogdan Ionut Dobrovat, Anca Haisan, Victorita Sorodoc
RESEARCH PAPER
sαKlotho protein is a useuful biomarker and a promising cardioprotective agent in acute heart failure
Joanna Płonka, Agnieszka Olejnik, Anna Klus, Ewa Gawrylak-Dryja, Natalia Wężyk, Lidia Rzepiela, Klaudia Dąbrowska, Iwona Bil-Lula, Marek Gierlotka
CLINICAL RESEARCH
Risk factors for cerebral hyperperfusion syndrome after carotid revascularization: a meta-analysis involving 158,624 participants
CLINICAL RESEARCH
Causal association of plasminogen activators and their inhibitors with Alzheimer’s disease: a Mendelian randomization study
EXPERIMENTAL RESEARCH
β-estradiol alleviates hypoxic-ischemic brain damage in neonatal rats through the GPER1-mediated AKT/NF-κB signaling pathway
Guangyun Zhang, Dawei Yuan, Tiegang Lv, Huafeng Li, Yanli Zhang, Yong Ding, Juan Cui, Min Li, Jing Yu, Jing Chen, Xiangping Xu
Editor's Choice
RESEARCH PAPER
A simplified cardiac amyloidosis score is associated with all-cause and cardiovascular disease mortality and morbidity, in the general population: the Ikaria Study.
Christina Chrysohoou, Demosthenes Panagiotakos, Dimitrios Tsiachris, Kyriakos Dimitriadis, George Lazaros, Kostas Tsioufis, Christodoulos Stefanadis
RESEARCH PAPER
Efficacy and safety of proton pump inhibitors for diabetes mellitus in patients with gastroesophageal reflux disease: A meta-analysis
CLINICAL RESEARCH
Uncovering the role of RPL8 in glutathione synthesis-dependent ferroptosis control in hepatocellular carcinoma
SYSTEMATIC REVIEW/META-ANALYSIS
The incidence of catheter-related bloodstream infections in different central venous access devices: a network meta-analysis of randomized controlled trials
Editor's Choice
RESEARCH PAPER
Long-Term Trends in Intensive Care Unit Hospitalizations in Poland: Study Based on the National Hospital Registry, 2012-2021
Krzysztof Kanecki, Paweł Goryński, Michał Kowalczyk, Katarzyna Lewtak, Piotr Tyszko, Michał Rząd, Aneta Nitsch-Osuch
Editor's Choice
RESEARCH PAPER
The Role of Vaccination, Testing, and Public Restriction Policies in COVID-19 Mortality and Incidence: Insights from Global Burden of Disease Regions
CLINICAL RESEARCH
Assessment of special hospital meals for diabetic patients. Discrepancies between provided meals, model menus and dietary guidelines: a hospital diet medical investigation (HDMI) study
Alicja M. Jodczyk, Alicja Kucharska, Mariusz Panczyk, Natalia Adamczyk, Karolina Turlej, Piotr Wierzbiński, Marcin Barylski, Adam R. Poliwczak, Maciej Janiszewski, Artur Mamcarz, Daniel Śliż
RESEARCH PAPER
Mesenchymal Stem Cells Suppress Kidney Injury molecule-1 Associated with Inhibition of Renal PKC/ NF-Kβ / STAT3 Fibrotic Signaling Pathway in Rats with Diabetic Nephropathy
Hasnaa A. Ebrahim, Asmaa Mohammed AlMohanna, Ayed A. Shati, Mohammed A. Alshehri, Thoraya Mohamed Elhassan A-Elgadir, Hailah M. Almohaimeed, Mohamed A. Haidara, Sara Adel Hosny, Amal Dawood, Asmaa M. ShamsEldeeen
RESEARCH PAPER
Investigating the Multi-Targeted Pharmacological profile of an Exopolysaccharide from Bacillus rugosus SYG20 via In Vitro Evaluation of its Antioxidant, Anti-inflammatory, Anti-diabetic, Wound Healing, and Antimicrobial Properties
Maha A. Alharbi, Aisha M.A Shahlol, Mona Othman I. Albureikan, Khalid Johani, Mohamed Gamal Elsehrawy, Mohammad El-Nablaway, Fayez M. Saleh, Ahmed Farouk Basyony, Shadi A. Zakai, Ahmed Ghareeb
EXPERIMENTAL RESEARCH
Effect of paeoniflorin on neuronal autophagy and Notch expression in tethered spinal cord in rats
CLINICAL RESEARCH
Correlation between SLC39A8 gene and body constitution-related phenotypes and hearing loss: a Mendelian randomization-based study
SYSTEMATIC REVIEW/META-ANALYSIS
Prevalence and incidence of chest wall deformities in children below 18 years old: the first systematic review and meta-analysis
BASIC RESEARCH
Long noncoding RNA RP11-704M14.1 acts as a sponge of miR-6756-5p to promote neuronal proliferation by regulating ALOX15 expression
STATE OF THE ART PAPER
Recent advances in immune checkpoint inhibitor-based therapy of advanced hepatocellular carcinoma
CLINICAL RESEARCH
LncRNA KTN1-AS1 drives tumor progression in non-small cell lung cancer through the microRNA-153-3p/KLF5 axis
CLINICAL RESEARCH
YTHDF3-mediated m6A modification facilitates osteosarcoma progression through the FSP1-CoQ10-NAD(P)H axis to suppress ferroptosis
CLINICAL RESEARCH
The association between mixed exposure to per- and polyfluoroalkyl substances and the risk of diabetes
CLINICAL RESEARCH
Symptom characteristics in self-observation and directional preference in patients with low back pain undergoing McKenzie therapy
CLINICAL RESEARCH
The effects of exposure to the Great Chinese Famine during the fetal stage and childhood on prevalence of hypertension in adulthood
CLINICAL RESEARCH
The relationship between ghrelin and iron metabolism in beta thalassaemia major patients
CLINICAL RESEARCH
Causal associations of circulating inflammatory proteins with sepsis: a two-sample Mendelian randomization study
CLINICAL RESEARCH
Which multimorbidity clusters are associated with longer hospital stays in hypertensive patients?
CLINICAL RESEARCH
Cutaneous ulcers in anti-MDA5-positive dermatomyositis with rapidly progressive interstitial lung disease: a multicentre retrospective cohort study
Gang Wang, Ru Yang, Dong Yan, Lei Zhang, Lingxiao Xu, Fenghong Yuan, Ju Li, Min Wu, Zhanyun Da, Hua Wei, Lei Zhou, Songlou Yin, Jian Wu, Yan Lu, Dinglei Su, Lin Liu, Longxin Ma, Xiaoyan Xu, Huijie Liu, Tianli Ren, Yinshan Zang, Zhichun Liu
CLINICAL RESEARCH
Mitigating inflammatory response in breast cancer patients: the inhibitory effect of acupuncture and emotional nursing on the ST8SIA6-AS1/LINC00504/p38 pathway
CLINICAL RESEARCH
A comprehensive analysis of immune characteristics and clinical prognosis in Asian COVID-19 patients infected with SARS-CoV-2 Omicron strain XBB sub-variants: a retrospective study of 450 cases
Fenge Li, Yupeng Wang, Mengli Jin, Hongli Li, Jin Yan, Jiandong Hu, Xianfeng Zhang, Chunwa Wu, Luqing Wei
CLINICAL RESEARCH
Exosomal hsa_circ_0035277 enhances the malignancy of gastric cancer by interacting with the m6A reader ELAVL1
CLINICAL RESEARCH
Prenatal ultrasound reassessment of the corpus callosum based on cortical connectivity information
CLINICAL RESEARCH
Age-related macular degeneration in the context of an update from the Global Burden of Disease Study 2019
CLINICAL RESEARCH
Red blood cell distribution width-to-albumin ratio: a prognostic biomarker of sepsis patients
CLINICAL RESEARCH
Early prediction of placenta accreta spectrum by evaluation of risk factors and ultrasound
Caihong Hu, Weishe Zhang, Chenlin Pei, Yuelan Liu, Yiran Fu, Qiaozhen Peng, Biaobiao Wang, Qi Li, Jingrui Huang
CLINICAL RESEARCH
Electrocardiographic repolarization parameters in children with arrhythmias and excessive body weight
Joanna Jaromin, Grażyna Markiewicz-Łoskot, Lesław Szydłowski, Agnieszka Kulawik, Agnieszka Chlebowczyk, Ewa Moric-Janiszewska
CLINICAL RESEARCH
SNHG15 is involved in the progression of atherosclerosis through targeted regulation of miR-370-3p and bioinformatics analysis
CLINICAL RESEARCH
A predictive nomogram for post-acute pancreatitis diabetes mellitus: a retrospective study
BASIC RESEARCH
METTL3-mediated miR-4534 maturation promotes IVDD progression by targeting the Sirt6-mediated Nrf2/HO-1 pathway
CLINICAL RESEARCH
Novel biotargets of colorectal cancer peritoneal metastasis
Ye Gu, Qiang Liu, LeLe Li, Lingyun Li, Dongchao Xu, Liyun Zheng, Lu Xie, Sile Cheng, Hongzhang Shen, Yanbing Jie, Yifeng Zhou, Jianfeng Yang, Hangbin Jin, Xiaofeng Zhang
CLINICAL RESEARCH
LncRNA NEAT1 contributes to multiple myeloma progression via upregulating ARPC5 by sponging miR-133a
Fujue Wang, Piaorong Zeng, Zhongwei Lu, Xingxing Long, Cong Luo, Juan Zuo, Yixiong Cao, Feng Wen, Junjun Li, Zeyu Luo
SYSTEMATIC REVIEW/META-ANALYSIS
Association of stress, anxiety and depression with temporomandibular disorders in young adults – a systematic review
RESEARCH PAPER
Melatonin Enhances the Viability of Random-Pattern Skin Flaps by Activating the NRF2 pathway
CLINICAL RESEARCH
The effect of trehalose administration on the serum expression levels of microRNAs associated with lipid metabolism and the autophagy process in patients with myocardial infarction – post-hoc analysis of the IR-TREAT trial
Shiva Ganjali, Atena Mansouri, Željko Reiner, Tannaz Jamialahmadi, Seyed Adel Moallem, Sepideh Salehabadi, Maciej Banach, Amirhossein Sahebkar
CLINICAL RESEARCH
New-onset hypertension is not associated with systemic changes in inflammatory cytokine levels
Anna Dzieża-Grudnik, Olga Siga, Jolanta Walczewska, Barbara Wizner, Tomasz P Mikołajczyk, Joanna Sulicka-Grodzicka, Tomasz Grodzicki
CLINICAL RESEARCH
Predictive value of imaging manifestations of supratentorial hemorrhage in hematoma enlargement and clinical prognosis
RESEARCH PAPER
The interaction of maternal obesity and administered betamethasone in the development of fetal respiratory distress syndrome
Mehmet Ak, Mefkure Eraslan Sahin, Erdem Sahin, Cevat Rıfat Cündübey, İlknur Çöl Madendağ, Yusuf Madendag, Osman Baştuğ
CLINICAL RESEARCH
5E-led hospital-community-family care in patients with lung cancer surgery: it does work
RESEARCH PAPER
miR-10b-5p regulates venous endothelial cells in deep venous thrombosis by targeting MFG-E8
RESEARCH PAPER
Galectin-3 regulates skeletal muscle loss via TGFβ1-Smad2/3 signaling activation in mice
RESEARCH PAPER
Demarcated by bronchial or vascular landmarks? a study on the lower borders of the lower paratracheal lymph nodes
CLINICAL RESEARCH
Fat-free muscle index predicts overall survival in mass-forming intrahepatic cholangiocarcinoma patients: a sex-stratified analysis
Hualing Li, Han Zhang, Zhouyan Liao, Qiufeng Liu, Dong Kuang, Yan Luo, Xuemei Hu, Yang Yang, Zhen Li
RESEARCH PAPER
Acute poisonings among children and adolescents- results of the analysis of 401 cases
RESEARCH PAPER
Therapeutic effect of Lactobacillus reuteri DSM 17938 on feeding intolerance in preterm infants
RESEARCH PAPER
Hyperglycemic crisis and Parkinson disease: A retrospective cohort study based on nationwide data
Kun-Ming Chung, Chung-Han Ho, Yi-Chen Chen, Chien-Chin Hsu, Hung-Jung Lin, Jhi-Joung Wang, Kang-Ting Tsai, Chien-Cheng Huang
CLINICAL RESEARCH
Identification and validation of immune pathway subtyping in glioblastoma to predict clinical prognosis and immunotherapy response in patients
CLINICAL RESEARCH
The influence of gender on hip range of motion, hip muscle strength, gluteus medius thickness and M-mode ultrasound examination in asymptomatic university athletes: a cross-sectional study
Angel Gonzalez-de-la-Flor, Carlos Romero-Morales, Maria Garcia-Arrabe, Fabien Guerineau, Fermín Valera-Garrido, Francisco Minaya-Muñoz, Fernando García-Sanz, Jaime Almazan-Polo
STATE OF THE ART PAPER
Innovative technology for rapid molecular diagnostics: COVID-19 and other respiratory tract infections
Mariusz Gujski, Emilian Snarski, Katarzyna Dzierżanowska-Fangrat, Piotr Hoffman, Wojciech Braksator, Marcin Czech, Piotr Przygodzki, Jacek Walczak, Izabela Pieniążek, Maciej Grys, Jacek Mucha
BASIC RESEARCH
A novel seven-immune-gene-based model to improve prediction of prognosis of clear cell renal cell carcinoma
RESEARCH PAPER
Metformin attenuates the progression of esophageal squamous cell carcinoma by downregulating miR-141-3p to enhance SCEL
CLINICAL RESEARCH
Unique spectrum of driver gene mutations in patients with non-small cell lung carcinoma from coal-manufacturing districts in Southwest China
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Bioinformatics analysis and experiments identify CD74 as a potential immune target in ovarian carcinoma
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Cervical Mucus SLPI is a Predictive Biomarker for Timing of Delivery in Nulliparous Term Pregnancies with Unfavorable Cervix
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Trehalose-induced alterations in serum expression levels of microRNAs associated with vascular inflammation in patients with coronary artery disease - the pilot results from the randomized controlled trial.
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Fresh autologous blood transfusion reverses erythrocytes damage by reducing oxidative stress via promoting mitochondrial metabolism and M2 macrophages polarization
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Oral immunotherapy prevents ventilator-associated pneumonia in premature infants: a meta-analysis and systematic review
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Association of the IL-4R Q576R polymorphism with asthma: a meta-analysis
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The etiologic role of Epstein-Barr virus and cytomegalovirus infections in breast cancer development: a meta-analysis of case-control studies
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Reticulocyte hemoglobin equivalent as a diagnostic parameter of iron deficiency anemia in infants age 1–4 months
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Coexistence of low testosterone and metabolic syndrome associated with increased arterial stiffness in male patients with type 2 diabetes
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IL-36γ promotes psoriasis-like features in keratinocytes in an imiquimod-induced murine model of psoriasis
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Influence of pulsed magnetic field therapy on hand function post flexor tendon repair: a randomized controlled trial
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Iron metabolism disorder and oxidative damage levels in placenta are involved in preeclampsia
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Green formulation and characterization of Fe nanoparticles containing Calendula extract and investigation of the antioxidant, cytotoxic and anti-human cholangiocarcinoma properties
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Knockdown of SNW1 ameliorates brain microvascular endothelial cells injury by inhibiting NLRP3 inflammasome activation
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H2S treatment improves protective effect of mesenchymal stem cell-derived exosomes on renal ischemia/reperfusion fibrosis by suppressing inflammatory signaling of TGF-β and NF-κB as well as radical oxygen species generation
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Anti-leukemia properties of cadmium nanoparticles in in vitro and in vivo conditions: a chemobiological study
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Saturated fatty acid-induced cardiomyopathy with diastolic dysfunction can be ameliorated by changing the quality of fatty acids to monounsaturated fatty acid
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Calendula officinalis green-mediated silver nanoparticles: formulation, characterization and assessment of colorectal cancer activities
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SYSTEMATIC REVIEW/META-ANALYSIS
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PLK1 downregulation by RO3280 prevents cell proliferation, migration, and invasion via the Wnt/β-catenin pathway in prostate cancer
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COVID-19: access to information, health service, daily life facility and risk perception of foreigners during the coronavirus pandemic in South Korea
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Novel formulation, cytotoxicity, antioxidant, and anti-human lung cancer properties of gold nanoparticles containing Verbascum thapsus L. leaf aqueous extract
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Efficacy and safety of lipegfilgrastim for prophylaxis of chemotherapy-induced neutropenia in breast cancer patients in Poland
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Anti-human ovarian cancer, cytotoxicity, and antioxidant effects of Nigella sativa green-formulated Au nanoparticles: describing a new chemotherapeutic supplement
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An immune-related long non-coding RNA signature predicts prognosis in glioblastoma patients
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Bioinformatics analysis and biological experiments support an emerging role of ELK3 in glioma
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Genetic factors that may affect the risk of developing thrombosis in patients with myeloproliferative disorders
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Development and validation of a nutritional risk screening scale for stroke patients
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miRNA-325-3p overexpression mitigates partial bladder outlet obstruction (PBOO) by regulating the TLR4/NF-kB(p65) pathway
Zhaofei Liu, Yiduo Zhou, Ziyang Liu, Yi Huang, Jie Gao, Le Shu, Ye He, Sicong Zhang, Zhengsen Chen, Baixin Shen, Zhongqing Wei, Liucheng Ding
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Rehabilitative ultrasound imaging for the assessment of selected morphometric parameters of the flexor hallucis longus muscle in healthy individuals: An inter- and intra- rater reliability study
Carlos Romero, Vanesa Abuín Porras, Emmanuel Navarro Flores, Patricia Palomo López, Victoria Mazoteras Pardo, Ana María Jiménez Cebrián, Daniel López López, BLANCA de la cruz torres
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Infections and antibiotic therapy in patients after spine surgery in a 5-year follow-up study
Joanna Baranowska, Alicja Baranowska, Paweł Baranowski, Tadeusz Płusa, Wojciech Białowąs, Marek Rybarczyk, Rafał Konieczny
CLINICAL RESEARCH
ERK knockdown suppresses cell biological activities via regulation of CD59 in breast cancer
Fei Qu, Yanru Cui, Shixin Yang, Zhihua Li, Jingxian Ding, Wensong Wei, Yufeng Zou, Pinghua Hu, Haolong Ding, Zhibing Zhou, Qihua Jiang, Bing Zhou, Liping Yan, Qianwen Ouyang
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The role of latency period on the preterm premature rupture of membranes: implication for treatment
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The pyruvate kinase activity in peripheral and uterine blood in women with atypical endometrial hyperplasia and endometrial cancer
Marek Dziechciowski, Barbara Zapała, Monika Piwowar, Olaf Chmura, Krzysztof Skotniczny, Magdalena Duda-Wiewiórka, Bogdan Solnica, Kazimierz Pityński
BASIC RESEARCH
Anti-small cell lung cancer and collagenase inhibition properties of hydroxysafflor yellow A
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Allicin depresses biological activities of pancreatic cancer cells by regulating miRNA-339-5p/ZNF-689 axis
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The micro-elimination approach - a new way of tackling hepatitis C in paediatric population
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Long non-coding RNA STARD13-AS suppresses glioma cell biological activities by vitro study
CLINICAL RESEARCH
IL-33/ST2 signaling promotes TF expression by regulating NF-κB activation in coronary artery endothelial microparticles
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Gentiana macrophylla exhibits a potential therapeutic effect on osteoarthritis (OA) via modulating disease-related proteins
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The effect of Thymbra spicata extract and its bioactive component Thymol on non-small-cells lung cancer cell line A549
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Hsa_circ_0001461 as a novel biomarker in patients with primary focal segmental glomerulosclerosis
Xiaoyi Cai, Jiayi Zhang, Mei Tan, Zichuan Xu, Huiying Deng, Ye Chen, Huabin Yang, Xia Gao, Yingjie Li, Yan Zou
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Adenosine A2a Receptors Improve Hypoxic Pulmonary Arterial Hypertension Via Mitochondrial ATP-sensitive Potassium Channels
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Melatonin Enhances Chondrocytes Survival Through Hyaluronic Acid Production and Mitochondria Protection
Zhi-Qiang Liu, Jingjing Wang, Amrish Thapa, Ying Xie, Jing Guo, Xin Li, Hongmei Jiang, Yixuan Wang, Ziyi Peng, Sheng Wang, Jingya Wang, Xianhui Li, Lingqun Ye
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Relationship between postmenopausal osteoporosis and glucocorticoid receptor gene (NR3C1) polymorphism in a Turkish population
CLINICAL RESEARCH
A pre-clinical trial study on afzelin: anti-human lung cancer, anti-cholinesterase, and anti-glucosidase properties
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Factors potentially influencing case fatality rate in different stages of COVID-19 outbreak in Europe
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Changes in the quality of life of patients with Blount’s disease undergoing simultaneous bilateral varus deformity correction with the use of the Ilizarov method.
Łukasz Szelerski, Sławomir Żarek, Radosław Górski, Karol Mochocki, Ryszard Górski, Andżelika Pajchert Kozłowska, Paweł Małdyk, Piotr Morasiewicz
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Investigation of IgG anti-oxLDL antibody levels and HDL and LDL subclasses in patients with ST-segment elevation acute myocardial infarction
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Urine flora imbalance and new biomarkers in prostate cancer and benign prostatic hyperplasia
CLINICAL RESEARCH
Study on the potential effect of multi-AGC kinase AT13148 on the Notch signaling pathway in glioblastoma
Yanan Li, Guosheng Han, Weijie Min, Mengmeng Li, Maomao Wang, Chao Chen, Yi Chen, Laixing Wang, Zhijian Yue
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ANLN promotes cell migration and invasion through RhoA-ROCK signaling in cervical cancer
CLINICAL RESEARCH
Mesenchymal stromal cells suppress hepatic fibrosis via modulating expression of fibronectin and integrin and inhibiting DNA fragmentation in rats
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Age-related differences in the prehospital management of 2,500 patients with sudden cardiac arrest
Janusz Sielski, Karol Kaziród-Wolski, Marta Solnica, Mirosław Data, Dominika Kukla, Kamil Woźnica, Marcin Sadowski
META-ANALYSIS
Correlations of three polymorphisms in β2-adrenergic receptor gene with chronic obstructive pulmonary disease risk and related phenotypes: a meta-analysis
Guan Wang, Danni He, Yang Wang, Haifeng Jin, Lijie Yao, Yang Jiang, Deshan Zhou, Lei Shen, Wenquan Niu
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A comparison of the risk factors of diabetic retinopathy between type 2 diabetes mellitus patients with and without metabolic syndrome
CLINICAL RESEARCH
GnRH antagonist versus depot GnRH agonist protocol in polycystic ovary syndrome (PCOS): analysis using propensity score matching
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Elderly patients and the idea of having medication deprescribed: a mixed method study in Portuguese primary health care
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Correlation of serum 25-hydroxyvitamin-D3 , hs-CRP, and homocysteine in women with gestational diabetes mellitus
BASIC RESEARCH
Expression of ADAMTS13 in human endometrium and its potential role in recurrent pregnancy loss
CLINICAL RESEARCH
Midterm outcomes after primary stenting in treatment of atherosclerotic iliac arteries
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Genomic variations in SARS-CoV-2 strains at the target sequences of nucleic acid amplification tests
Canhui Cao, Ruidi Yu, Shaoqing Zeng, Dan Liu, Wenjian Gong, Ruyuan Li, Siyuan Wang, Yuan Yuan, Jianhua Chi, Jiahao Liu, Yang Yu, Xiaofei Jiao, Guangyao Cai, Ning Jin, Fei Ye, Qinglei Gao
CLINICAL RESEARCH
Assessment of odontogenic changes in computed tomography of patients with chronic sinusitis
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Arterial stiffness as a risk factor for hypotension during induction of general anesthesia
Ianis Siriopol, Ioana Grigoras, Dimitrie Siriopol, Adi Ciumanghel, Daniel Rusu, Mihaela Blaj, Adrian Covic
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Comparison of Different Stenting Techniques of Coronary Bifurcation Lesions: A Network Meta-Analysis of 7601 Patients
Orit Barrett, Lital Hadad, Ala Abu Dogosh, Romain Didier, Hector Garcia-Garcia, Yigal Abramowitz, Carlos Cafri, Gabriel Rosenstein, Miri Merkin, Aref El Nasasra, Doron Zahger, Edward Koifman
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Mitochondrial content and oxidative damage in full-term placentas from SGA, LGA and AGA infants pregnant women
Joel Ramírez-Emiliano, Gloria Barbosa-Sabanero, Martha Olivia Solís-Martínez, Mariana Fernanda Mina-Bravo, Edgar Alejandro Martínez-Escamilla Edgar A, Victoriano Pérez-Vázquez
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Local anesthetic Ropivacaine protects rats from myocardial ischemia/reperfusion injury by inhibition of COX-2
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Clinical characteristics and outcome of 55 cases of hepatoblastoma relapses
Wei-ling Zhang, Hui-min Hu, Yi-zhuo Wang, Yi Zhang, Jing Li, Yuan Wen, Tian Zhi, Ya-nan Gao, Dong-sheng Huang
CLINICAL RESEARCH
Dihydromyricetin alleviates endothelial inflammatory response through the IRE1α/NF-κB signaling pathway in sepsis
Xifeng Wang, Xiaomin Xu, Yu Peng Yang, Xin Xin, Zekang Li, Qimeng Wang, Xiaoli Li, Yun Hou, Lianshuang Zhang
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Effects of Zhuyu Annao on Hippocampal Neuronal Apoptosis and Cognitive Disorder in a Rat Model of Ischemic Brain Injury
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Ubiquitin specific peptidase 49 inhibits renal fibrosis through protein phosphatase magnesium-dependent1A-mediated Smad2/3 pathway
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Cardiovascular complications according to severity of renal artery stenosis based on Doppler ultrasound
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AnnexinA7 and CAP1 are associated with regulating tumor cell adhesion molecule expression and biological behavior
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The outcomes of multivisceral resection for primary T4b colorectal cancer in a tertiary referral centre: a propensity score matching analysis
Marcin Włodarczyk, Kasper Maryńczak, Przemysław Gajewski, Radzisław Trzciński, Michal Mik, Adam J. Dziki, Andrew Hill, Łukasz Dziki
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Administration of simvastatin halts progression of cirrhosis via up-regulating expression of miR-34a and interleukin-10 in rats
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Long non-coding RNA NEAT1/miR-320b/MSI2 axis regulates cisplatin resistance in ovarian cancer
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Risk factors and prediction model construction of post-operative atrial fibrillation after thoracic surgery in Chinese patients
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Genomic signatures in pediatric advanced stage Burkitt lymphoma/leukemia in a Chinese population detected by next generation sequencing
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MiR-125b-5p enclosed in hypoxic HK2 cell-derived extracellular vesicles alleviates renal ischemia-reperfusion injury by regulating NLRC5
Kai Xu, Lifeng Zhang, Lei Zhang, Lei Zhang, Ze Zhang, Siwei Qian, Xiangyu Zou, Shuqiu Chen, Li Zuo, ming chen, Guangyuan Zhang
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Serum S100A8 as an early diagnostic biomarker in patients with community-acquired pneumonia
Pu Fang, Ling Zheng, Peng Cao, Chen Zhang, Jun Fei, Zheng Xu, Chun-Mei Feng, Hui Zhao, You-Jin Lu, Lin Fu
CLINICAL RESEARCH
The prognostic impact of CD49d protein and mRNA expression in patients with chronic lymphocytic leukaemia
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CLINICAL RESEARCH
The polymorphism rs2227513 can affect expression of IL-22 and proliferation of fibroblast-like synoviocytes, which leads to progression of rheumatoid arthritis
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Icariin interferes with TDP43-induced inflammatory factor secretion and inhibits the JNK and p38 MAPK signaling pathway in vitro
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Predictive risk factors for worse outcomes in COVID-19 patients with different clinical features at baseline
Elisabetta Schiaroli, Anna Gidari, Giovanni Brachelente, Sabrina Bastianelli, Alfredo Villa, Carla Ferri, Daniela Francisci
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Survival analysis of advanced lung cancer patients undergoing personalised treatment or chemotherapy in a real clinic
Justyna Błach, Paweł Krawczyk, Juliusz Pankowski, Jarosław Buczkowski, Izabela Chmielewska, Małgorzata Frąk, Artur Szlubowski, Piotr Krudys, Robert Kieszko, Kamila Wojas-Krawczyk, Katarzyna Reszka, Tomek Kucharczyk, Janusz Milanowski
RESEARCH PAPER
Blood count-derived inflammatory markers predict time to Bacillus Calmette-Guérin failure in high-risk non-muscle-invasive bladder cancer
Aleksander Ślusarczyk, Zapała Piotr, Karolina Garbas, Łukasz Zapała, Tomasz Borkowski, Piotr Radziszewski
RESEARCH PAPER
Determination of multiple vitamins in 178 patients undergoing chemotherapy for lung cancer
lanqing liang, wei yu, boning cai, qianqian wang, xiang huang, jing chen, mingyue zeng, yao wang, baolin qu, fang liu
CLINICAL RESEARCH
Both AA genotype of rs165599 and Val/Val genotype of rs4680 in COMT are associated with an increased risk of recurrence of prostate cancer
RESEARCH PAPER
Risk prediction for death and end-stage renal disease does not parallel the real-life trajectory of older patients with advanced chronic kidney disease – a Romanian center experience.
Nastasa Andra, APETRII MUGUREL, Onofriescu Mihai, Nistor Ionut, Voroneanu Luminita, Hussien Hani, Covic Adrian
BASIC RESEARCH
Anti-tumor effects of isoliquiritigenin in Bcl-2/Bax and PCNA expression of T24 human bladder cancer cells
RESEARCH PAPER
Improvement in age- and sex-dependent mortality in patients with atrial fibrillation between 2011 and 2016 – a nationwide retrospective study from Hungary
Zoltan Kiss, László Márk, Béla Herczeg, Dániel Aradi, György Rokszin, Ibolya Fábián, Krisztián Horváth, István Wittmann, Róbert Gábor Kiss, Csaba Dézsi, Zoltán Csanádi, Béla Merkely
CLINICAL RESEARCH
The correlation between serum insulin-like growth factor 1 level and body weight in children with a height less than the 10th percentile
BASIC RESEARCH
Mechanism of resistin-induced enhancement of proliferation and migration of ovarian cancer cells
CLINICAL RESEARCH
Association of vitamin D receptor and CYP2R1 mRNA expression with pulmonary tuberculosis
CLINICAL RESEARCH
Interplay between IL-17 family members and angiogenic cytokines in subjects with systemic sclerosis
Ewa Robak, Zofia Gerlicz-Kowalczuk, Agata Liszewska, Bozena Dziankowska-Bartkowiak, Anna Wozniacka, Jaroslaw Bogaczewicz
RESEARCH PAPER
Long non-coding RNA SNHG16 contributes to progression of carotid atherosclerosis by regulating miR-30c-5p/ADAM10 axis
BASIC RESEARCH
Vitamin D ameliorated endothelial cell damage induced by diabetes via regulation of lncRNA MEG3 in human umbilical vein endothelial cells
Hua Wei, Qiongfang Zhang, Jun Li, Jing Yang, Bin Huang, Chun-chun Huang, Ying-chuan Wang, Jing-qian Hu, Xi Wei
CLINICAL RESEARCH
Long-term follow-up results of patients diagnosed with nonspecific pleuritis by video-assisted thoracoscopic surgery biopsy
RESEARCH PAPER
Protective effect of casticin in myocardial ischemia/reperfusion injury in rats via attenuation of oxidative stress and inflammation
BASIC RESEARCH
Ellagic acid inhibited cervical cancer growth via blocking the AKT/mTOR/STAT3 pathway
EXPERIMENTAL RESEARCH
Oleuropein modulates over-proliferation of keratinocytes in mice with imiquimodmediated psoriasis and inhibits differentiation of TH17 cells through the JAK3/STAT3 axis
CLINICAL RESEARCH
A novel homozygous ALMS1 protein truncation mutation (c.2938dupA) revealed variable clinical expression among Saudi Alström syndrome patients
Amnah Yousuf Bdier, Faten Abdullah Al-Qahtani, Prashant Kumar Verma, Naeem Abdulmoneem Alshoaibi, Nuha Mohammed Alrayes, Noor Ahmad Shaik, Roger Sik Yin Foo, Zahurul Alam Bhuiyan, Jumana Y. Al-Aama
RESEARCH PAPER
Panax notoginseng saponins elicits anti-cancer effect by modulating miR-760/SMAD4 signaling in osteosarcoma
BASIC RESEARCH
lncRNA SNHG6 improves placental villous cell function in an in vitro model of gestational diabetes mellitus
RESEARCH PAPER
Lycopene prevents cisplatin-induced liver tissue damage, without affecting concentrations of TNF-α or iNOS/NO inflammatory pathway
Aleksandar Rankovic, Vanja Nickovic, Tanja Novakovic, Nebojsa Mitic, Biljana Krdzic, Jadranka Mitic, Gordana Nikolic, Dusan T Sokolovic
RESEARCH PAPER
G protein-coupled estrogen receptor GPR30 exerts vasoprotective effects in apolipoprotein E-deficient mice
Julian Jehle, Ulrich M. Becher, Moritz Nöthel, Sandra Adler, Katharina Groll, Georg Nickenig, Vedat Tiyerili
RESEARCH PAPER
ST2L expression on monocyte subsets is associated with the severity of acute coronary syndrome and plaque vulnerability
RESEARCH PAPER
Preoperative clinical and renal ultrasonography variables associated with improved systolic and diastolic blood pressure reduction after renal artery stenting
Anna Kabłak-Ziembicka, Agnieszka Rosławiecka, Rafał Badacz, Andrzej Sokołowski, Daniel Rzeźnik, Piotr Pieniążek, Jacek Legutko, Krzysztof Żmudka, Tadeusz Przewłocki
RESEARCH PAPER
The use of prognostic scales in upper gastrointestinal tract bleeding.
Czesław Osuch, Mateusz Rubinkiewicz, Piotr Tylec, Alicja Dudek, Orłowska Monika, Dorota Długosz, Katarzyna Truszkiewicz, Jan Witowski, Andrzej Matyja
RESEARCH PAPER
Lipotoxicity induced pancreatic beta cell damage is associated with GPR119/MST1/FoxO1 Pathway
Lirong Ma, Jianning Li, Hui Song, Yan Li, Yue Wang, Yansong Luan, Yuhan Li, Hui Qi, Yi Yang, Lei Cai
CLINICAL RESEARCH
Variability of PT-INR values measured by point of care devices INRatio/INRatio 2 and CoaguChek XS and standard laboratory method. A cross-sectional study
EXPERIMENTAL RESEARCH
Hyperbaric oxygen effects on the alveoli-capillary unit in a murine model of pulmonary arterial hypertension
Pedro J. Curi-Curi, Maria C. Castillo-Hernandez, Miguel Chavez-Martinez, Lilia Loredo-Mendoza, Eduardo Rios-Garcia, Alexandre Kormanovski-Kovzova, Gustavo Guevara-Balcazar
EXPERIMENTAL RESEARCH
Resveratrol (3,4ʹ,5-trihydroxy-trans-stilbene) or caffeic acid phenethyl ester supplementation prevents premature ovarian insufficiency due to chemotherapy
RESEARCH PAPER
Ultrasound screening for cervical, abdominal and scrotal malignant and benign abnormalities in children
Grzegorz Jedrzejewski, Agnieszka Zaucha-Prazmo, Albert Matera, Magdalena Maria Wozniak, Marcin Inglot, Mikolaj Pietkiewicz, Andrzej Pawel Wieczorek, Jerzy Kowalczyk
STATE OF THE ART PAPER
May nutrients and dietary supplements influence the gut-lung microbiota axis in chronic obstructive pulmonary disease and exacerbations?
RESEARCH PAPER
A rare variant in the IL22RA2 gene is associated with unexplained recurrent pregnancy loss in Han Chinese women
Ying Cui, Zeng-Ming Li, Jin Chen, Xin Zeng, Fa-Ying Liu, Chun-Yan Yang, Qian Ye, Zi-Yu Zhang, Yong Luo, Xiao-Yong Chen, Yang Zou
CLINICAL RESEARCH
COVID-19 disease: novel clinical manifestations and therapeutic exploration
Chun Liu, Qiang Huang, PingXi Wang, HuaPing Wu, ShuKai Deng, Dan Liu, ChunFeng Xiang, Qiang Gao, FanWei Zeng, XiangDe Zheng
Long-term prognosis in patients suffering from myocardial infarction with non-obstructive coronary arteries, ST-segment elevation myocardial infarction, infective myocarditis and tako-tsubo cardiomyopathy – all-cause mortality comparison
Magdalena Jędrychowska, Rafał Januszek, Wojciech Wańha, Krzysztof Piotr Malinowski, Wojciech Wojakowski, Krzysztof Bartuś, Andrzej Surdacki, Dariusz Dudek, Stanisław Bartuś
SYSTEMATIC REVIEW/META-ANALYSIS
Development of erectile dysfunction in men treated for major depressive disorder with selective serotonin reuptake inhibitors: a systematic review
RESEARCH PAPER
Up-regulation of peroxiredoxin 3 by high-risk human papillomavirus in cervical cancer cells
RESEARCH PAPER
miR-210 regulates vascular endothelial cell apoptosis in arteriosclerosis obliterans through the JAK1-STAT3 pathway
CLINICAL RESEARCH
COVID-19 in Poland: potential associations with epidemiology, population and healthcare quality
CLINICAL RESEARCH
Comparison of clinical characteristics, treatment, in-hospital and 12-month outcomes in patients after myocardial infarction with ejection fraction < 40% with or without atrial fibrillation
Przemysław Trzeciak, Radosław Sierpiński, Jacek Niedziela, Wojciech Wojakowski, Marek Gierlotka, Mariusz Gąsior, Zbigniew Kalarus
CLINICAL RESEARCH
The effect of beinaglutide on visceral fat and bodyweight in obese type 2 diabetic patients
Gui-Ying Wang, Hui-Qin Wang, Feng-Juan Zhang, Ai-Fu Jiao, Ying-Yu Li, Ji-Min Zhang, Zheng-Li Huang, Yan-Hong Gao, Yan-Jun Chi, Cun-Ming Ma, Jian-Dong Xin, Ai-Xu Duan, Tao Meng, Yin-Bing Wang
CLINICAL RESEARCH
Comparison of the efficacy of vindesine and leurocristine for pediatric acute lymphoblastic leukemia and their effects on quality of life
CLINICAL RESEARCH
An observational study of clinical inertia among patients with type 2 diabetes mellitus in a tertiary care hospital
Piranee Kaewbut, Natapong Kosachunhanun, Arintaya Phrommintikul, Dujrudee Chinwong, John Hall, Surarong Chinwong
BASIC RESEARCH
The relationship between RSUME and VHL/HIF-1α signalling pathway in renal cell carcinoma
Yuanliang Wang, Xin Wang, Faliang Zhao, Anjian Chen, Tiangcai Liang, Yang Du, Hao Li, Jiang Du, Zifeng Fu, Guobiao Liang
BASIC RESEARCH
lncRNA LINC00152 knockdown suppressed hepatic cancer biological activity
Yajun Ma, Xuli Yang, Yong Xu, Rongping Zhou, Gang Chen, Deseng Fan, Shikun Luo, Zhili Shen, Dong Yang
CLINICAL RESEARCH
Comparison of the effectiveness of penicillin and broad-spectrum β-lactam antibiotics in the treatment of community-acquired pneumonia in children
Magnetic resonance white matter changes in patients with obstructive sleep apnoea. The subset of the PURE-MIND (Prospective Urban and Rural Epidemiological) cohort study
Katarzyna Postrzech-Adamczyk, Artur Nahorecki, Jagoda Jacków-Nowicka, Maria Wołyniec, Maciej Karczewski, Robert Skomro, Anna Zimny, Andrzej Szuba
EXPERIMENTAL RESEARCH
miR-93-5p attenuates apoptosis and autophagy by regulating SRY-box2 in spinal cord-injured rats in vivo and PC12 cells in vitro
RESEARCH PAPER
The Status Quo of Doctors’ Occupational Burnout and Its Correlation with the Cognition of Doctor-patient Relationship Tensity
EXPERIMENTAL RESEARCH
Overexpression of PGC-1α reduces inflammation and protects against focal cerebral ischaemia/reperfusion injury
CLINICAL RESEARCH
Kawasaki disease in Latvia 2012–2019: epidemiology and rate of resistance to initial treatment
RESEARCH PAPER
CircRNA LRIG3 knockdown inhibits hepatocellular carcinoma progression by regulating miR-223-3p and MAPK/ERK pathway
BASIC RESEARCH
The impact of diffuse large B-cell lymphoma-derived exosomes on macrophage polarisation and cytokine release
CLINICAL RESEARCH
Influence of childhood overweight and obesity on foot and lower limb pain in a population of primary school children
Ana María Jiménez-Cebrián, Pedro Daniel Roman-Bravo, María Francisca Morente-Bernal, Juan Antonio Alonso-Ríos, Blanca De-la-Cruz-Torres, Carlos Romero-Morales, Emmanuel Navarro-Flores, Alonso Montiel-Luque
EXPERIMENTAL RESEARCH
P2X7 blockade inhibits the growth of breast cancer in 4T1 breast cancer-bearing mice by NLRP3/caspase 1 pathway
RESEARCH PAPER
Risk of migraine in iron deficiency anemia patients with or without iron supplementation usage: a nationwide database analysis
BASIC RESEARCH
miR-338-3p attenuates oxaliplatin resistance in gastric cancer cells via targeting thrombospondin-1
Does climate change affect the chronobiological trends in the occurrence of acute coronary syndrome?
Łukasz Kuźma, Anna Kurasz, Marta Maria Niwińska, Małgorzata Zalewska-Adamiec, Hanna Bachórzewska-Gajewska, Slawomir Dobrzycki
EXPERIMENTAL RESEARCH
Effect of thymoquinone on cyclophosphamide-induced injury in the rat urinary bladder
EXPERIMENTAL RESEARCH
Expression pattern of circulating long non-coding RNA GAS5 as a novel biomarker in non-small cell lung cancer patients
Natasa Vesovic, Natasa Tosic, Teodora Karan Djurasevic, Zoran Andric, Darko Zdravkovic, Sonja Pavlovic, Dragana Jovanovic
BASIC RESEARCH
Polyether antibiotics K-41A and K-41Am inhibit HIV-1 replication via suppressing the activities of HIV-1 reverse transcriptase and integrase
Xin Liu, Jiemei Chu, Chun Gui, Weibo Liao, Fengxiang Qin, Xi Hu, Bingyu Liang, Junjun Jiang, Jiegang Huang, Chuanyi Ning, Jiang Chen, Jianhua Ju, Jingzhen Lai, Jie Liu, Bo Zhou, Li Ye, Hao Liang
CLINICAL RESEARCH
Remimazolam tosilate in patients undergoing upper gastrointestinal endoscopy: a multicenter, randomized, dose-exploration, positive-controlled, parallel-group, phase II trial
Shao-Hui Chen, Tang-Mi Yuan, Jiao Zhang, Hua Bai, Ming Tian, Chu-Xiong Pan, Hong-Guang Bao, Su Min, Xiao-Ju Jin, Guo-Zhong Chen, Tai-Di Zhong, Yu-Guang Huang
CLINICAL RESEARCH
Association of genetic polymorphisms on methotrexate toxicity in patients with rheumatoid arthritis
María José Zarzuelo Romero, María del Mar Maldonado Montoro, Cristina Pérez Ramírez, Noelia Márquez Pete, Almudena Sánchez Martín, Fernando Martínez Martínez, Miguel Ángel Calleja Hernández, María Carmen Ramírez Tortosa, Alberto Jiménez Morales
CLINICAL RESEARCH
It is not just a game. Do soccer matches affect cardiovascular events?
Lukasz Kuźma, Krzysztof Struniawski, Piotr Sielatycki, Szymon Pogorzelski, Hanna Bachórzewska-Gajewska, Sławomir Dobrzycki
RESEARCH PAPER
Amplification of Cord Blood-Derived Cytotoxic T Lymphocytes using HL-60 cell Derived Exosomes
CLINICAL RESEARCH
Association of micronuclei frequency and other nuclear anomalies with flaxseed diet in metabolic syndrome patients
José de Jesús López-Jiménez, Alina García-Ruvalcaba, Ana Cecilia Méndez-Magaña, Claudia Elizabeth Granados-Manzo, Lizet Yadira Rosales-Rivera, Elisa García-Morales, Priscila Ayala-Buenrostro, Lorena Viridiana De Alba-Espinoza, Ana Carolina Ángel-del Río, Fabian Gaona-Sánchez, Ana Lilia Fletes-Rayas
CLINICAL RESEARCH
The effects of three kinds of non-steroidal anti-inflammatory drugs on postoperative pain and on the serum levels of tumour necrosis factor-α and substance P in paediatric patients following orthopaedic hip surgery
Jin-Li Guo, Yi-Ting Yue, Hong Cheng, Yong-Bo Huang, Wen-Bin Li, Xian-Yan Yan, Chao-Na Gao, Xiu-Juan Guo
EXPERIMENTAL RESEARCH
The anti-lung cancer effect of ethyl acetate extract from Wenxia Formula in vivo via the Hedgehog-Gli1 signaling pathway mediated by cancer associated fibroblasts
Analysis of inflammatory markers in patients with abnormal circadian rhythm of blood pressure
Néstor Vázquez Agra, Ana Teresa Marques Afonso, Antón Cruces Sande, Ignacio Novo Veleiro, José Enrique López Paz, Álvaro Hermida Ameijeiras
SYSTEMATIC REVIEW/META-ANALYSIS
Reduced expression of CDH1 and its prognostic value in pancreatic cancer: a meta-analysis
EXPERIMENTAL RESEARCH
Upregulation of Foxo3a protects neurons against hypoxia-ischaemia injury
Rongjia Lu, Huajie Cai, Yu Liao, Keman Liao, Jianhua Wang, Bin Liao, Shaofu Zhou, Shaoping Chen, Renhua Huang, Ping Zhang, Sunhai Zhou
FIB-4 index associated with mortality risk of patients with systemic lupus erythematosus: a large retrospective cohort study
Ziyi Jin, Xuebing Feng, Dandan Wang, Wenyou Pan, Lin Liu, Min Wu, Huaixia Hu, Xiang Ding, Hua Wei, Yaohong Zou, Xian Qian, Meimei Wang, Jian Wu, Juan Tao, Jun Tan, Zhanyun Da, Miaojia Zhang, Jing Li, Lingyun Sun
CLINICAL RESEARCH
A clinical study on the value of carotid cistern drainage during intracranial aneurysm clipping
CLINICAL RESEARCH
Effectiveness of low-tube current for reducing radiation dose in cerebral CT perfusion
CLINICAL RESEARCH
Assessing the role of serum prolactin levels and coding region somatic mutations of the prolactin gene in Saudi uterine leiomyoma patients
Hanan Abdelhalim ElSokary, Layla Saleh Abdullah, Amani Ujaimi, Nora Naif Sahly, Nisma Mansouri, Babajan Banaganapalli, Noor Ahmad Shaik, Ramu Elango, Nabeel Bondagji
CLINICAL RESEARCH
Cyclin-dependent kinase 8/β-catenin signalling contributes to tumourigenesis in prostate cancer and can be regulated by miR-216a-5p
CLINICAL RESEARCH
Clinical characteristics and management of hyperlipoproteinemia in patients with chronic coronary heart disease in Slovakia
RESEARCH PAPER
Therapeutic effect of YSY01 on osteoarthritis in rabbit: involvement of suppressing signaling pathway of NF-kB and MMP-9
CLINICAL RESEARCH
Placental DNA methylation in caesarean sections – a pilot study
Aneta Słabuszewska-Jóźwiak, Marta Włodarczyk, Michał Ciebiera, Joanna Zwolińska, Cezary Wojtyła, Grażyna Nowicka, Grzegorz Jakiel, Dorota Raczkiewicz
EXPERIMENTAL RESEARCH
PRMT5, regulated by lncRNA ZFAS1/miR-150-5p, promoted androgen-independent prostate cancer migration and invasion
BASIC RESEARCH
Allicin suppressed bladder cancer cell biological activities via regulation of the miR-26b-5p/PTEN axis in an in vitro study
EXPERIMENTAL RESEARCH
Myrcene enhances the cardioprotective effect through matrix remodelling in an experimental model of heart failure
EXPERIMENTAL RESEARCH
Evaluation for CpG island methylation of FASN and SREBP promoter in Mongolian gerbil NAFLD model
CLINICAL RESEARCH
Pulmonary dysfunction in children with Duchenne muscular dystrophy may occur earlier than we thought – analysis using novel methodology based on z-scores
Eliza Wasilewska, Sylwia Małgorzewicz, Jarosław Meyer-Szary, Karolina Sledzinska, Marek B. Niedoszytko, Ewa Jassem, Jolanta Wierzba
CLINICAL RESEARCH
Effect of genetic variants in FAS and let-7a on radiation-induced intestinal toxicity in the treatment of prostate cancer
EXPERIMENTAL RESEARCH
SATB2-AS1 acts as a miR-299-3p sponge to facilitate tumorigenesis in human non-small cell lung cancer
CLINICAL RESEARCH
Curcumin affects the prognosis of renal cell carcinoma through a negative feedback loop of H19/miR-675/HDAC/CTCF
EXPERIMENTAL RESEARCH
TUG1 acts as a biomarker to predict the relapse of gastric cancer after endoscopic submucosal dissection
EXPERIMENTAL RESEARCH
MicroRNA-223-3p attenuates the angiotensin II-dependent ROS effect on cell viability by targeting NLRP3 in H9c2 cells
CLINICAL RESEARCH
The association of calf circumference and all-cause, cardiovascular and cerebrovascular mortality: results from the National Health and Nutrition Examination Surveys
Jia Yi Huang, Lin Liu, Kenneth Lo, Yuling Yu, Chao Lei Chen, Geng Shen, Bin Zhang, Yu Qing Huang, Ying Qing Feng
CLINICAL RESEARCH
Correlation between granulocyte colony-stimulating factor and the Notch signaling pathway in ischemic brain injury
SYSTEMATIC REVIEW/META-ANALYSIS
Diagnostic performance of wireless fractional flow reserve: a meta-analysis
EXPERIMENTAL RESEARCH
Metformin alleviates intervertebral disc degeneration by upregulating MMP-1 expression via the KDM6A/SOX9/miR-202-3p/MMP-1 signaling pathway
| eISSN: | 1896-9151 |
| ISSN: | 1734-1922 |
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